| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-nitrososarcosine 32.64 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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114 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:P17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KLHL9 | kelch-like family member 9 | 4.6868 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 4.5509 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 4.3013 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 4.15015 |
| SPAG4 | sperm associated antigen 4 | 4.06355 |
| GRB10 | growth factor receptor-bound protein 10 | 3.88578 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.85305 |
| CCNF | cyclin F | 3.2502 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase | 3.00665 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 2.81155 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.7883 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 | 2.62 |
| MEST | mesoderm specific transcript | 2.59705 |
| SCARB1 | scavenger receptor class B, member 1 | 2.57385 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 2.53655 |
| WDR7 | WD repeat domain 7 | 2.4968 |
| FZD7 | frizzled class receptor 7 | 2.48047 |
| LTF | lactotransferrin | 2.44415 |
| MSRA | methionine sulfoxide reductase A | 2.4208 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 2.39085 |
| FAM193B | family with sequence similarity 193, member B | 2.37745 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.3545 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.35315 |
| NAMPT | nicotinamide phosphoribosyltransferase | 2.33113 |
| WDR41 | WD repeat domain 41 | 2.30135 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 | 2.27225 |
| C4A | complement component 4A (Rodgers blood group) | 2.23787 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 2.23238 |
| TCTN1 | tectonic family member 1 | 2.2182 |
| C8A | complement component 8, alpha polypeptide | 2.20825 |
| EMID1 | EMI domain containing 1 | 2.19615 |
| SATB1 | SATB homeobox 1 | 2.19215 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 2.18915 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 2.1756 |
| UBA3 | ubiquitin-like modifier activating enzyme 3 | 2.169 |
| DUSP14 | dual specificity phosphatase 14 | 2.13845 |
| ITGB8 | integrin, beta 8 | 2.13352 |
| BAHD1 | bromo adjacent homology domain containing 1 | 2.13265 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 2.13042 |
| CERT1 | ceramide transporter 1 | 2.1252 |
| H2BC12 | H2B clustered histone 12 | 2.12187 |
| PMVK | phosphomevalonate kinase | 2.1127 |
| STOML1 | stomatin (EPB72)-like 1 | 2.11217 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 2.10135 |
| BAAT | bile acid CoA:amino acid N-acyltransferase | 2.10055 |
| MPDU1 | mannose-P-dolichol utilization defect 1 | 2.09805 |
| PRKCQ | protein kinase C, theta | 2.08068 |
| FGF17 | fibroblast growth factor 17 | 2.07855 |
| HPGDS | hematopoietic prostaglandin D synthase | 2.0775 |
| CLDN4 | claudin 4 | 2.0756 |
| ZNF571 | zinc finger protein 571 | 2.0734 |
| FASTK | Fas-activated serine/threonine kinase | 2.06385 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 | 2.04085 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 | 2.0258 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | 2.02155 |
| HPR | haptoglobin-related protein | 2.02015 |
| ABCB11 | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | 2.00595 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA8 | heat shock 70kDa protein 8 | -5.62813 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -5.02655 |
| CDK4 | cyclin-dependent kinase 4 | -4.3636 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -4.17915 |
| HSPA1A | heat shock 70kDa protein 1A | -3.98975 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.5393 |
| TATDN2 | TatD DNase domain containing 2 | -3.5151 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | -3.2856 |
| EI24 | etoposide induced 2.4 | -2.8587 |
| NOSIP | nitric oxide synthase interacting protein | -2.85365 |
| VAT1 | vesicle amine transport 1 | -2.79875 |
| ARCN1 | archain 1 | -2.7023 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.6903 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -2.6903 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.65865 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -2.656 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -2.64 |
| PCBP1 | poly(rC) binding protein 1 | -2.62785 |
| TOR1A | torsin family 1, member A (torsin A) | -2.57863 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -2.56245 |
| TP53RK | TP53 regulating kinase | -2.54515 |
| OGN | osteoglycin | -2.4681 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.46475 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -2.46275 |
| CCNH | cyclin H | -2.4333 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | -2.3723 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -2.37015 |
| UBQLN2 | ubiquilin 2 | -2.35405 |
| USP11 | ubiquitin specific peptidase 11 | -2.3513 |
| GPC3 | glypican 3 | -2.3302 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) | -2.3098 |
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | -2.2858 |
| ASRGL1 | asparaginase like 1 | -2.2157 |
| NUP93 | nucleoporin 93kDa | -2.21465 |
| EIF3CL | eukaryotic translation initiation factor 3, subunit C-like | -2.21233 |
| RPS5 | ribosomal protein S5 | -2.2058 |
| EIF3G | eukaryotic translation initiation factor 3, subunit G | -2.1961 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | -2.19225 |
| INTS3 | integrator complex subunit 3 | -2.1716 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.16525 |
| BAG3 | BCL2-associated athanogene 3 | -2.14805 |
| ALCAM | activated leukocyte cell adhesion molecule | -2.12842 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -2.12685 |
| NDUFB4 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa | -2.1176 |
| RPN1 | ribophorin I | -2.1154 |
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | -2.10885 |
| RPL8 | ribosomal protein L8 | -2.107 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -2.09948 |
| H3-3A | H3.3 histone A | -2.07606 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.07085 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.07017 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -2.0362 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -2.03038 |
| SAMM50 | SAMM50 sorting and assembly machinery component | -2.03003 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.0231 |
| GMPS | guanine monphosphate synthase | -2.0217 |
| TRIP12 | thyroid hormone receptor interactor 12 | -2.02025 |
