CRCGN016_MCF10A.TP53.M_24H:P21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o,o-dimethyl s-[2-(methylamino)-2-oxoethyl] dithiophosphate 11.23 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

1042 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:P21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COMP cartilage oligomeric matrix protein 6.2468
WIF1 WNT inhibitory factor 1 5.79843
COL11A1 collagen, type XI, alpha 1 5.54937
AGR2 anterior gradient 2 4.60899
TGFB3 transforming growth factor, beta 3 4.21777
MNAT1 MNAT CDK-activating kinase assembly factor 1 4.06771
PROS1 protein S (alpha) 4.01483
TRAPPC11 trafficking protein particle complex 11 3.96135
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.90765
RNF111 ring finger protein 111 3.89314
CADM1 cell adhesion molecule 1 3.83321
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3.82823
RSF1 remodeling and spacing factor 1 3.82187
LYN LYN proto-oncogene, Src family tyrosine kinase 3.75948
C5 complement component 5 3.71221
BET1 Bet1 golgi vesicular membrane trafficking protein 3.69742
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.56119
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 3.51656
GATAD1 GATA zinc finger domain containing 1 3.48562
GPR183 G protein-coupled receptor 183 3.48231
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 3.44174
ASPN asporin 3.41983
LGMN legumain 3.39681
ZNF451 zinc finger protein 451 3.35199
GRK3 G protein-coupled receptor kinase 3 3.31792
TPO thyroid peroxidase 3.28972
MEF2C myocyte enhancer factor 2C 3.27382
GOLGA8F golgin A8 family, member F 3.25077
EYA3 EYA transcriptional coactivator and phosphatase 3 3.25042
DDN dendrin 3.24936
ATAD2B ATPase family, AAA domain containing 2B 3.21964
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.2184
EPHA4 EPH receptor A4 3.21138
BMP4 bone morphogenetic protein 4 3.20169
CDK8 cyclin-dependent kinase 8 3.19806
GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 3.1921
RHOBTB1 Rho-related BTB domain containing 1 3.18263
RNASE6 ribonuclease, RNase A family, k6 3.16988
SETD6 SET domain containing 6 3.16019
HPGDS hematopoietic prostaglandin D synthase 3.14557
PDGFRL platelet-derived growth factor receptor-like 3.13779
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 3.13528
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 3.12997
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 3.12593
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 3.1241
TXNL4B thioredoxin-like 4B 3.12254
MORC3 MORC family CW-type zinc finger 3 3.1133
FLCN folliculin 3.10764
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 3.08306
FKBP14 FK506 binding protein 14, 22 kDa 3.06609
FAM117A family with sequence similarity 117, member A 3.05525
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 3.04996
CRY2 cryptochrome circadian clock 2 3.04627
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 3.04069
KLHL3 kelch-like family member 3 3.03813
COL5A2 collagen, type V, alpha 2 3.03493
TBC1D31 TBC1 domain family, member 31 3.0156
FRS2 fibroblast growth factor receptor substrate 2 3.00535
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 3.00516
GDF9 growth differentiation factor 9 2.99609
GPC4 glypican 4 2.98564
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 2.97484
TENM4 teneurin transmembrane protein 4 2.97065
ZNF274 zinc finger protein 274 2.96566
TMEM268 transmembrane protein 268 2.96139
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 2.94961
BRIX1 BRX1, biogenesis of ribosomes 2.94698
WDR7 WD repeat domain 7 2.94452
METTL2A methyltransferase like 2A 2.94446
AIRIM AFG2 interacting ribosome maturation factor 2.94012
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.93773
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 2.92423
GHR growth hormone receptor 2.91724
TG thyroglobulin 2.90756
MATN3 matrilin 3 2.90586
CDC73 cell division cycle 73 2.89972
UVRAG UV radiation resistance associated 2.89778
OMD osteomodulin 2.88912
ZNF280D zinc finger protein 280D 2.88173
TPSAB1 tryptase alpha/beta 1 2.88055
PXDNL peroxidasin-like 2.87918
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 2.86496
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2.86277
NOX4 NADPH oxidase 4 2.86006
RAP1A RAP1A, member of RAS oncogene family 2.85955
MAP9 microtubule-associated protein 9 2.85062
LDOC1 leucine zipper, down-regulated in cancer 1 2.85022
KRIT1 KRIT1, ankyrin repeat containing 2.84913
SMNDC1 survival motor neuron domain containing 1 2.84653
TIPRL TOR signaling pathway regulator 2.84505
LOC128966622 putative protein N-methyltransferase FAM86B2 2.84351
HIRA histone cell cycle regulator 2.84201
DACT1 dishevelled-binding antagonist of beta-catenin 1 2.83623
STXBP3 syntaxin binding protein 3 2.83472
LZTR1 leucine-zipper-like transcription regulator 1 2.825
REV1 REV1, polymerase (DNA directed) 2.80447
ADGRF5 adhesion G protein-coupled receptor F5 2.79685
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.79539
CHST10 carbohydrate sulfotransferase 10 2.79113
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.78815
GUSB glucuronidase, beta 2.77735
ZSCAN16 zinc finger and SCAN domain containing 16 2.76366
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 2.75677
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.75602
FAM124B family with sequence similarity 124B 2.75325
EFR3B EFR3 homolog B (S. cerevisiae) 2.75003
PRSS23 protease, serine, 23 2.74548
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 2.73771
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 2.73531
TTC27 tetratricopeptide repeat domain 27 2.73458
NEMF nuclear export mediator factor 2.73077
STAT5B signal transducer and activator of transcription 5B 2.72859
PPP1R12B protein phosphatase 1, regulatory subunit 12B 2.72682
ZNF280B zinc finger protein 280B 2.72085
NLK nemo-like kinase 2.72025
C2CD3 C2 calcium-dependent domain containing 3 2.7159
COL5A1 collagen, type V, alpha 1 2.7057
TOGARAM1 TOG array regulator of axonemal microtubules 1 2.70502
DDAH1 dimethylarginine dimethylaminohydrolase 1 2.70308
RAB27A RAB27A, member RAS oncogene family 2.70071
LRRC15 leucine rich repeat containing 15 2.69595
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 2.69123
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.68607
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.68052
RNF2 ring finger protein 2 2.67797
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 2.67723
VASH2 vasohibin 2 2.67413
KRABD4 KRAB domain containing 4 2.67405
TESMIN testis expressed metallothionein like protein 2.67382
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 2.66801
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.66711
GLB1L galactosidase, beta 1-like 2.66522
LYRM9 LYR motif containing 9 2.65652
PTK7 protein tyrosine kinase 7 (inactive) 2.65506
ACAA1 acetyl-CoA acyltransferase 1 2.65492
AKT3 v-akt murine thymoma viral oncogene homolog 3 2.65486
AP3M2 adaptor-related protein complex 3, mu 2 subunit 2.64884
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 2.64875
FOS FBJ murine osteosarcoma viral oncogene homolog 2.64832
CDKN2AIP CDKN2A interacting protein 2.64377
ADGRA2 adhesion G protein-coupled receptor A2 2.63946
BCAS2 breast carcinoma amplified sequence 2 2.63734
CD69 CD69 molecule 2.63332
CDK20 cyclin-dependent kinase 20 2.63053
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.62846
HLA-DMA major histocompatibility complex, class II, DM alpha 2.62803
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.62742
RINT1 RAD50 interactor 1 2.62336
WNT3 wingless-type MMTV integration site family, member 3 2.61702
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 2.61514
ZNF8 zinc finger protein 8 2.6089
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 2.60852
SYNE1 spectrin repeat containing, nuclear envelope 1 2.60821
ZNHIT6 zinc finger, HIT-type containing 6 2.60321
KRT38 keratin 38, type I 2.6032
NANOS2 nanos homolog 2 (Drosophila) 2.59864
CCDC70 coiled-coil domain containing 70 2.59629
GSAP gamma-secretase activating protein 2.59095
CCN5 cellular communication network factor 5 2.59013
BMP2K BMP2 inducible kinase 2.5882
CNKSR1 connector enhancer of kinase suppressor of Ras 1 2.58386
PTPRD protein tyrosine phosphatase, receptor type, D 2.58296
BIN2 bridging integrator 2 2.57833
POSTN periostin, osteoblast specific factor 2.57181
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 2.56589
ADAM9 ADAM metallopeptidase domain 9 2.56563
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.56479
ETV6 ets variant 6 2.56407
CTSK cathepsin K 2.56355
TEC tec protein tyrosine kinase 2.56265
RPH3A rabphilin 3A 2.56023
COL8A2 collagen, type VIII, alpha 2 2.55898
PANX1 pannexin 1 2.55516
PAGE4 P antigen family, member 4 (prostate associated) 2.55296
USP20 ubiquitin specific peptidase 20 2.55045
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 2.54608
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 2.54413
LOC122526780 uncharacterized LOC122526780 2.53667
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 2.53017
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.52441
GOLGA8N golgin A8 family, member N 2.52285
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 2.51843
SOX5 SRY (sex determining region Y)-box 5 2.51758
GATA3 GATA binding protein 3 2.51641
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 2.51493
RFPL2 ret finger protein-like 2 2.51488
MXRA5 matrix-remodelling associated 5 2.51338
PTGIS prostaglandin I2 (prostacyclin) synthase 2.5118
ZNF260 zinc finger protein 260 2.51165
AHCTF1 AT hook containing transcription factor 1 2.5108
ARPP21 cAMP-regulated phosphoprotein, 21kDa 2.50943
AOC2 amine oxidase, copper containing 2 (retina-specific) 2.50887
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 2.50522
RIPOR2 RHO family interacting cell polarization regulator 2 2.50163
PARM1 prostate androgen-regulated mucin-like protein 1 2.49958
CDH18 cadherin 18, type 2 2.49896
MMP13 matrix metallopeptidase 13 2.49487
THBS2 thrombospondin 2 2.49474
TRAPPC8 trafficking protein particle complex 8 2.49336
IPCEF1 interaction protein for cytohesin exchange factors 1 2.49263
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 2.49242
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.49037
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 2.49012
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 2.48869
NELL1 NEL-like 1 (chicken) 2.48594
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 2.4845
ZNF85 zinc finger protein 85 2.48427
LTN1 listerin E3 ubiquitin protein ligase 1 2.48394
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 2.47799
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 2.47775
PAK1IP1 PAK1 interacting protein 1 2.47681
CCR1 chemokine (C-C motif) receptor 1 2.47314
FUBP3 far upstream element (FUSE) binding protein 3 2.47252
CETN3 centrin, EF-hand protein, 3 2.47247
BRS3 bombesin-like receptor 3 2.47236
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.46994
FAM3C family with sequence similarity 3, member C 2.45929
ARID4B AT rich interactive domain 4B (RBP1-like) 2.45887
PRELID3A PRELI domain containing 3A 2.45861
OPRK1 opioid receptor, kappa 1 2.45796
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.45757
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 2.45687
KERA keratocan 2.44944
FN3K fructosamine 3 kinase 2.44908
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 2.44786
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 2.44235
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.44227
RAP1GAP RAP1 GTPase activating protein 2.44103
HINFP histone H4 transcription factor 2.43787
RNF208 ring finger protein 208 2.43711
HOXA6 homeobox A6 2.43554
MYO1F myosin IF 2.4312
GCC2 GRIP and coiled-coil domain containing 2 2.42933
TXK TXK tyrosine kinase 2.42767
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 2.42722
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2.42494
NCOR1 nuclear receptor corepressor 1 2.42378
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 2.4226
PLEKHO1 pleckstrin homology domain containing, family O member 1 2.42229
GTPBP8 GTP-binding protein 8 (putative) 2.42084
RYR3 ryanodine receptor 3 2.41943
SKI SKI proto-oncogene 2.41785
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 2.41706
PLA2G15 phospholipase A2, group XV 2.41353
HDAC9 histone deacetylase 9 2.412
GLMN glomulin, FKBP associated protein 2.41064
L2HGDH L-2-hydroxyglutarate dehydrogenase 2.40852
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 2.40826
PLS3 plastin 3 2.40678
NKX2-1 NK2 homeobox 1 2.40485
FBXL18 F-box and leucine-rich repeat protein 18 2.40411
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.40383
AGK acylglycerol kinase 2.40376
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 2.40264
CELF2 CUGBP, Elav-like family member 2 2.39939
MYLK myosin light chain kinase 2.39885
RLN2 relaxin 2 2.39847
WNT8B wingless-type MMTV integration site family, member 8B 2.39827
ZNF143 zinc finger protein 143 2.39514
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 2.39493
EGF epidermal growth factor 2.3945
RLF rearranged L-myc fusion 2.39102
TRIM24 tripartite motif containing 24 2.38907
CRYGD crystallin, gamma D 2.38526
GNA14 guanine nucleotide binding protein (G protein), alpha 14 2.38361
IFT74 intraflagellar transport 74 2.38174
MINPP1 multiple inositol-polyphosphate phosphatase 1 2.38077
CCDC91 coiled-coil domain containing 91 2.38016
GSG1 germ cell associated 1 2.37902
PI15 peptidase inhibitor 15 2.37475
KRT33B keratin 33B, type I 2.37361
CCN4 cellular communication network factor 4 2.36941
TCTA T-cell leukemia translocation altered 2.36729
ERCC6 excision repair cross-complementation group 6 2.36699
MTSS2 MTSS I-BAR domain containing 2 2.36544
MMP2 matrix metallopeptidase 2 2.36531
CRYM crystallin, mu 2.36204
SENP6 SUMO1/sentrin specific peptidase 6 2.3607
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 2.3591
MRPL44 mitochondrial ribosomal protein L44 2.35879
PDGFD platelet derived growth factor D 2.35822
SCN2B sodium channel, voltage gated, type II beta subunit 2.3561
SIDT1 SID1 transmembrane family, member 1 2.35593
CXCR4 chemokine (C-X-C motif) receptor 4 2.34859
CXCL14 chemokine (C-X-C motif) ligand 14 2.34838
UBE2D1 ubiquitin-conjugating enzyme E2D 1 2.34653
CREB5 cAMP responsive element binding protein 5 2.34446
EDNRA endothelin receptor type A 2.34277
TCP10L t-complex 10-like 2.34033
ZNF652 zinc finger protein 652 2.34023
CD300C CD300c molecule 2.33997
HPS4 Hermansky-Pudlak syndrome 4 2.33948
TNMD tenomodulin 2.33863
PHF21A PHD finger protein 21A 2.33814
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 2.33717
HIP1 huntingtin interacting protein 1 2.33413
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 2.3315
CDADC1 cytidine and dCMP deaminase domain containing 1 2.33068
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.33067
CDK3 cyclin-dependent kinase 3 2.33054
ZNF562 zinc finger protein 562 2.32967
KMT2D lysine (K)-specific methyltransferase 2D 2.32958
ZNF506 zinc finger protein 506 2.32834
SULF1 sulfatase 1 2.32794
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.32772
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.32694
LGALS12 lectin, galactoside-binding, soluble, 12 2.32671
ZNF74 zinc finger protein 74 2.32571
CT55 cancer/testis antigen 55 2.31811
POLI polymerase (DNA directed) iota 2.3151
LIPT1 lipoyltransferase 1 2.31216
IFRD1 interferon-related developmental regulator 1 2.311
CCL2 chemokine (C-C motif) ligand 2 2.31099
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.31062
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 2.30835
RRAGB Ras-related GTP binding B 2.30684
ROPN1B rhophilin associated tail protein 1B 2.3031
GCLC glutamate-cysteine ligase, catalytic subunit 2.30216
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.29999
CST4 cystatin S 2.29716
PRND prion protein 2 (dublet) 2.29628
ARMCX2 armadillo repeat containing, X-linked 2 2.29488
PLXDC2 plexin domain containing 2 2.29421
RECQL RecQ helicase-like 2.29355
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 2.29348
AVL9 AVL9 homolog (S. cerevisiase) 2.28372
CNGB3 cyclic nucleotide gated channel beta 3 2.28341
STYK1 serine/threonine/tyrosine kinase 1 2.28207
LMO3 LIM domain only 3 (rhombotin-like 2) 2.28033
CPED1 cadherin-like and PC-esterase domain containing 1 2.27847
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 2.27715
PRR7 proline rich 7 (synaptic) 2.27573
PER2 period circadian clock 2 2.27544
H2AJ H2A.J histone 2.27483
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 2.27468
PSG4 pregnancy specific beta-1-glycoprotein 4 2.2745
DNAAF8 dynein axonemal assembly factor 8 2.2713
ITGA8 integrin, alpha 8 2.27106
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 2.26483
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 2.26472
PLAAT1 phospholipase A and acyltransferase 1 2.26466
THAP12 THAP domain containing 12 2.26391
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 2.26254
EFCAB6 EF-hand calcium binding domain 6 2.26173
CLDN4 claudin 4 2.26165
COL11A2 collagen, type XI, alpha 2 2.26081
LY86 lymphocyte antigen 86 2.26052
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 2.25828
SLC6A16 solute carrier family 6, member 16 2.25738
IFNA6 interferon, alpha 6 2.25666
YEATS4 YEATS domain containing 4 2.25482
ZNF493 zinc finger protein 493 2.2537
BCOR BCL6 corepressor 2.25271
GGPS1 geranylgeranyl diphosphate synthase 1 2.25263
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.25199
ENC1 ectodermal-neural cortex 1 (with BTB domain) 2.25063
DRC11 dynein regulatory complex subunit 11 2.25043
RAB11FIP5 RAB11 family interacting protein 5 (class I) 2.25007
DEPDC5 DEP domain containing 5 2.24655
PTCD1 pentatricopeptide repeat domain 1 2.24321
DRD4 dopamine receptor D4 2.24075
PILRA paired immunoglobin-like type 2 receptor alpha 2.23897
STAP1 signal transducing adaptor family member 1 2.23821
STAT4 signal transducer and activator of transcription 4 2.23729
TULP2 tubby like protein 2 2.23556
SLC14A2 solute carrier family 14 (urea transporter), member 2 2.23552
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 2.23471
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 2.23311
CISD1 CDGSH iron sulfur domain 1 2.23
NCDN neurochondrin 2.22646
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 2.22505
ZNF460 zinc finger protein 460 2.22193
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 2.22097
SCNN1D sodium channel, non voltage gated 1 delta subunit 2.21963
GPATCH1 G patch domain containing 1 2.21815
MEGF8 multiple EGF-like-domains 8 2.21733
NLGN3 neuroligin 3 2.21722
COL14A1 collagen, type XIV, alpha 1 2.21705
PIWIL2 piwi-like RNA-mediated gene silencing 2 2.21333
KLHL29 kelch-like family member 29 2.21076
KIN Kin17 DNA and RNA binding protein 2.20923
ZNF669 zinc finger protein 669 2.20769
CA14 carbonic anhydrase XIV 2.20703
ACTR8 ARP8 actin-related protein 8 homolog (yeast) 2.20464
OVOL3 ovo-like zinc finger 3 2.20432
APOBR apolipoprotein B receptor 2.20378
VRK2 vaccinia related kinase 2 2.20242
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) 2.20111
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.2006
UBXN2B UBX domain protein 2B 2.20024
RNF19B ring finger protein 19B 2.19915
GAL3ST4 galactose-3-O-sulfotransferase 4 2.19767
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 2.19752
RBM48 RNA binding motif protein 48 2.19702
YIPF4 Yip1 domain family, member 4 2.19681
BBIP1 BBSome interacting protein 1 2.19645
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 2.19531
NEK4 NIMA-related kinase 4 2.19513
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 2.19474
GPATCH2 G patch domain containing 2 2.19436
TTBK2 tau tubulin kinase 2 2.19423
HILPDA hypoxia inducible lipid droplet-associated 2.19339
TBX3 T-box 3 2.19231
LUM lumican 2.19217
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 2.19127
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 2.19043
LOC128966601 pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial-like 2.19041
INPP5J inositol polyphosphate-5-phosphatase J 2.18856
DGCR2 DiGeorge syndrome critical region gene 2 2.18795
TMEM50A transmembrane protein 50A 2.18747
MYO5A myosin VA (heavy chain 12, myoxin) 2.1874
CEP112 centrosomal protein 112kDa 2.18722
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 2.18688
TMA16 translation machinery associated 16 homolog (S. cerevisiae) 2.1867
FAM8A1 family with sequence similarity 8, member A1 2.18617
FBXL2 F-box and leucine-rich repeat protein 2 2.18604
TIMP3 TIMP metallopeptidase inhibitor 3 2.18593
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 2.18345
INSIG2 insulin induced gene 2 2.1833
GPATCH2L G patch domain containing 2-like 2.18328
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) 2.18212
PHAF1 phagosome assembly factor 1 2.18182
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.18104
AMELY amelogenin, Y-linked 2.1806
TBX5 T-box 5 2.17994
MMP23B matrix metallopeptidase 23B 2.17938
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 2.17915
CSH2 chorionic somatomammotropin hormone 2 2.17883
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 2.17805
OCM2 oncomodulin 2 2.17798
GDAP2 ganglioside induced differentiation associated protein 2 2.17783
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 2.17711
OBP2B odorant binding protein 2B 2.17403
PKN1 protein kinase N1 2.17308
TESPA1 thymocyte expressed, positive selection associated 1 2.17265
HYAL4 hyaluronoglucosaminidase 4 2.17154
IMPACT impact RWD domain protein 2.17056
ITGB7 integrin, beta 7 2.17006
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 2.16968
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 2.16941
ZNF696 zinc finger protein 696 2.16912
SCAI suppressor of cancer cell invasion 2.16811
NID2 nidogen 2 (osteonidogen) 2.16754
CTSO cathepsin O 2.16641
DTNB dystrobrevin, beta 2.16638
CPA4 carboxypeptidase A4 2.16622
SMAD7 SMAD family member 7 2.16598
FAM120C family with sequence similarity 120C 2.16472
FGA fibrinogen alpha chain 2.16374
CD38 CD38 molecule 2.1633
FCF1 FCF1 rRNA-processing protein 2.16249
LRRC17 leucine rich repeat containing 17 2.16188
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 2.16147
STK38L serine/threonine kinase 38 like 2.1614
DEPTOR DEP domain containing MTOR-interacting protein 2.161
ZNF142 zinc finger protein 142 2.16065
FMOD fibromodulin 2.16064
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.15958
TMEM158 transmembrane protein 158 (gene/pseudogene) 2.15716
SNX27 sorting nexin family member 27 2.15707
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.15649
ZNF367 zinc finger protein 367 2.15536
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.15362
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 2.1524
IFFO1 intermediate filament family orphan 1 2.15214
ZNF135 zinc finger protein 135 2.15103
ISOC1 isochorismatase domain containing 1 2.15054
HUS1 HUS1 checkpoint homolog (S. pombe) 2.14784
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.14673
AURKC aurora kinase C 2.14672
MMUT methylmalonyl-CoA mutase 2.14625
TLR4 toll-like receptor 4 2.14577
VGLL4 vestigial-like family member 4 2.14471
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 2.14436
SCARF1 scavenger receptor class F, member 1 2.14392
PUS7 pseudouridylate synthase 7 (putative) 2.14382
ARMC8 armadillo repeat containing 8 2.14325
MANBA mannosidase, beta A, lysosomal 2.14301
ATP8B4 ATPase, class I, type 8B, member 4 2.14278
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 2.14111
TBC1D22B TBC1 domain family, member 22B 2.14024
WNT2 wingless-type MMTV integration site family member 2 2.139
GPX5 glutathione peroxidase 5 2.13863
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 2.13755
DOP1A DOP1 leucine zipper like protein A 2.13753
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.135
LYRM1 LYR motif containing 1 2.13473
MARK1 MAP/microtubule affinity-regulating kinase 1 2.13397
EMC2 ER membrane protein complex subunit 2 2.13351
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 2.13317
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1 2.1329
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.13288
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 2.13281
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 2.13255
TSPYL5 TSPY-like 5 2.13092
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 2.13074
EXPH5 exophilin 5 2.13072
LRRC32 leucine rich repeat containing 32 2.12757
ITSN2 intersectin 2 2.12707
APOE apolipoprotein E 2.12491
RWDD3 RWD domain containing 3 2.12454
TSHR thyroid stimulating hormone receptor 2.12267
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.12158
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.12044
RNF103-CHMP3 RNF103-CHMP3 readthrough 2.11968
TMEM248 transmembrane protein 248 2.11871
CSHL1 chorionic somatomammotropin hormone-like 1 2.11855
HHEX hematopoietically expressed homeobox 2.11845
DGKI diacylglycerol kinase, iota 2.11817
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 2.11661
TNP1 transition protein 1 (during histone to protamine replacement) 2.11565
PMFBP1 polyamine modulated factor 1 binding protein 1 2.11508
SLC16A4 solute carrier family 16, member 4 2.11454
PCDHGA5 protocadherin gamma subfamily A, 5 2.11385
TRIM11 tripartite motif containing 11 2.11268
MTMR3 myotubularin related protein 3 2.11259
LHX2 LIM homeobox 2 2.11191
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 2.11131
PSG3 pregnancy specific beta-1-glycoprotein 3 2.11012
ODR4 odr-4 GPCR localization factor homolog 2.10889
IQCE IQ motif containing E 2.10799
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 2.10763
TTC17 tetratricopeptide repeat domain 17 2.10609
IFT54 intraflagellar transport 54 2.10498
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 2.10487
ZNF223 zinc finger protein 223 2.10485
PTGDR2 prostaglandin D2 receptor 2 2.10329
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 2.10308
NMRK1 nicotinamide riboside kinase 1 2.10297
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2.10244
MRPL19 mitochondrial ribosomal protein L19 2.10058
ZMYM6 zinc finger, MYM-type 6 2.10058
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 2.09859
AFF3 AF4/FMR2 family, member 3 2.09811
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 2.09604
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.09558
ASTN1 astrotactin 1 2.09541
TMEM106B transmembrane protein 106B 2.09457
NUP42 nucleoporin 42 2.09338
PPARD peroxisome proliferator-activated receptor delta 2.09303
LONRF3 LON peptidase N-terminal domain and ring finger 3 2.0929
ZNF334 zinc finger protein 334 2.09246
TSKS testis-specific serine kinase substrate 2.09222
ZPBP zona pellucida binding protein 2.09115
SP4 Sp4 transcription factor 2.09095
SDHAF3 succinate dehydrogenase complex assembly factor 3 2.09048
ZSCAN18 zinc finger and SCAN domain containing 18 2.09044
NT5C2 5'-nucleotidase, cytosolic II 2.0903
KIF26B kinesin family member 26B 2.08905
GH1 growth hormone 1 2.08838
PLXDC1 plexin domain containing 1 2.0872
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 2.08697
BBS1 Bardet-Biedl syndrome 1 2.08356
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 2.08337
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 2.08288
PHACTR1 phosphatase and actin regulator 1 2.08246
E4F1 E4F transcription factor 1 2.08245
THUMPD2 THUMP domain containing 2 2.08223
KIF17 kinesin family member 17 2.08218
EPPIN epididymal peptidase inhibitor 2.08121
FOXE1 forkhead box E1 2.08048
BRDT bromodomain, testis-specific 2.07928
NFE2L3 nuclear factor, erythroid 2-like 3 2.07817
RPAP2 RNA polymerase II associated protein 2 2.07814
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 2.07651
PSIP1 PC4 and SFRS1 interacting protein 1 2.07559
CNKSR2 connector enhancer of kinase suppressor of Ras 2 2.07403
GGTLC1 gamma-glutamyltransferase light chain 1 2.07355
LMOD1 leiomodin 1 (smooth muscle) 2.07328
OSR2 odd-skipped related transciption factor 2 2.07225
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 2.07217
ACSM3 acyl-CoA synthetase medium-chain family member 3 2.07216
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 2.07083
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 2.07005
EREG epiregulin 2.06788
GTF2IRD2B GTF2I repeat domain containing 2B 2.06774
EPHX3 epoxide hydrolase 3 2.06737
ZNF780B zinc finger protein 780B 2.06736
SPIN2B spindlin family, member 2B 2.06569
ZBTB18 zinc finger and BTB domain containing 18 2.06529
COL10A1 collagen, type X, alpha 1 2.06477
ZNF710 zinc finger protein 710 2.06436
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 2.06432
GEMIN7 gem (nuclear organelle) associated protein 7 2.06408
CERT1 ceramide transporter 1 2.06339
HPCA hippocalcin 2.06232
GRM2 glutamate receptor, metabotropic 2 2.06216
NDEL1 nudE neurodevelopment protein 1-like 1 2.06125
USP27X ubiquitin specific peptidase 27, X-linked 2.06102
BCL7B B-cell CLL/lymphoma 7B 2.05901
P3H3 prolyl 3-hydroxylase 3 2.0569
KHK ketohexokinase (fructokinase) 2.05679
OXR1 oxidation resistance 1 2.05637
KIAA0408 KIAA0408 2.05601
CD101 CD101 molecule 2.05579
MCTP2 multiple C2 domains, transmembrane 2 2.05556
PDE5A phosphodiesterase 5A, cGMP-specific 2.05467
SYTL2 synaptotagmin-like 2 2.05425
RDH8 retinol dehydrogenase 8 (all-trans) 2.05398
PCP4 Purkinje cell protein 4 2.0533
ZNF276 zinc finger protein 276 2.05316
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.0531
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2.0523
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 2.05095
CTBS chitobiase, di-N-acetyl- 2.05074
ZNF112 zinc finger protein 112 2.05071
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.04975
ARHGAP15 Rho GTPase activating protein 15 2.04974
SPANXB1 SPANX family, member B1 2.04945
EPB41 erythrocyte membrane protein band 4.1 2.0489
ZNF136 zinc finger protein 136 2.04739
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 2.04723
CAVIN1 caveolae associated protein 1 2.0472
THY1 Thy-1 cell surface antigen 2.04663
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 2.04603
COL16A1 collagen, type XVI, alpha 1 2.04478
MGAT4C MGAT4 family, member C 2.04455
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 2.04444
TCN2 transcobalamin II 2.04392
COG5 component of oligomeric golgi complex 5 2.04317
OR7C1 olfactory receptor, family 7, subfamily C, member 1 2.043
TRIM52 tripartite motif containing 52 2.04289
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 2.0425
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 2.04206
PDE11A phosphodiesterase 11A 2.04174
TLK2 tousled-like kinase 2 2.0413
DENND2D DENN/MADD domain containing 2D 2.04083
TBX19 T-box 19 2.04052
ZNF225 zinc finger protein 225 2.04019
RCAN3 RCAN family member 3 2.03935
GINS1 GINS complex subunit 1 (Psf1 homolog) 2.03925
PDCL3 phosducin-like 3 2.03921
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 2.03782
IQGAP2 IQ motif containing GTPase activating protein 2 2.0378
ZNF442 zinc finger protein 442 2.03664
MAU2 MAU2 sister chromatid cohesion factor 2.03644
PRKACB protein kinase, cAMP-dependent, catalytic, beta 2.03534
CCDC30 coiled-coil domain containing 30 2.03464
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 2.03449
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 2.03247
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 2.03228
MYBPC2 myosin binding protein C, fast type 2.03213
OTUD3 OTU deubiquitinase 3 2.03204
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 2.03196
NEU3 sialidase 3 (membrane sialidase) 2.03152
DCK deoxycytidine kinase 2.03111
TRIM46 tripartite motif containing 46 2.02745
CCL7 chemokine (C-C motif) ligand 7 2.0255
DCAF17 DDB1 and CUL4 associated factor 17 2.02529
ACP5 acid phosphatase 5, tartrate resistant 2.02256
SCN8A sodium channel, voltage gated, type VIII alpha subunit 2.02019
FANCF Fanconi anemia, complementation group F 2.02011
IGSF6 immunoglobulin superfamily, member 6 2.0184
SLCO1B3 solute carrier organic anion transporter family, member 1B3 2.01837
ECHDC2 enoyl CoA hydratase domain containing 2 2.01826
AMOT angiomotin 2.01773
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 2.01712
DEFB126 defensin, beta 126 2.0169
SLC22A14 solute carrier family 22, member 14 2.01642
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 2.01605
LDHAL6B lactate dehydrogenase A-like 6B 2.01589
CREBL2 cAMP responsive element binding protein-like 2 2.01241
KDM5B lysine (K)-specific demethylase 5B 2.01239
DPH2 DPH2 homolog (S. cerevisiae) 2.01182
ITGA1 integrin, alpha 1 2.0115
PIAS4 protein inhibitor of activated STAT, 4 2.01057
WDR44 WD repeat domain 44 2.01011
TCEAL9 transcription elongation factor A like 9 2.01007
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 2.00892
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 2.00883
ARHGAP6 Rho GTPase activating protein 6 2.00734
DNAL4 dynein, axonemal, light chain 4 2.00717
TMEM151B transmembrane protein 151B 2.00648
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 2.00572
YOD1 YOD1 deubiquitinase 2.00528
ZFP69B ZFP69 zinc finger protein B 2.00395
SMIM29 small integral membrane protein 29 2.00371
FGR FGR proto-oncogene, Src family tyrosine kinase 2.00319
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.00312
ANGPTL2 angiopoietin-like 2 2.00196
TDRKH tudor and KH domain containing 2.00169

decreased expression

Symbol Name Standardized Value
ETFB electron-transfer-flavoprotein, beta polypeptide -9.10759
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -6.95105
CDK4 cyclin-dependent kinase 4 -6.24027
DDIT4 DNA-damage-inducible transcript 4 -5.51088
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -5.34358
PUF60 poly-U binding splicing factor 60KDa -5.33555
MT2A metallothionein 2A -5.22961
MT1X metallothionein 1X -5.1911
KRT14 keratin 14, type I -5.11909
VAT1 vesicle amine transport 1 -4.94655
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -4.88349
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.8761
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -4.80738
ADGRE5 adhesion G protein-coupled receptor E5 -4.73282
UFM1 ubiquitin-fold modifier 1 -4.71743
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -4.69493
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -4.65555
TUBA4A tubulin, alpha 4a -4.64418
TCERG1 transcription elongation regulator 1 -4.62211
CD81 CD81 molecule -4.45706
FABP5 fatty acid binding protein 5 (psoriasis-associated) -4.45706
ANXA2 annexin A2 -4.45706
PFN1 profilin 1 -4.42966
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -4.37132
BLCAP bladder cancer associated protein -4.32622
TM9SF3 transmembrane 9 superfamily member 3 -4.29681
TUFM Tu translation elongation factor, mitochondrial -4.22878
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.228
MSN moesin -4.19583
MRPS16 mitochondrial ribosomal protein S16 -4.18219
GFUS GDP-L-fucose synthase -4.11101
PLK1 polo-like kinase 1 -4.08057
TNIP1 TNFAIP3 interacting protein 1 -4.06088
HSPA8 heat shock 70kDa protein 8 -4.03541
PGAM4 phosphoglycerate mutase family member 4 -3.99903
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -3.99296
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -3.93756
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.85678
MVP major vault protein -3.83588
CDCA4 cell division cycle associated 4 -3.83263
CD44 CD44 molecule (Indian blood group) -3.83176
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.78224
AKT1 v-akt murine thymoma viral oncogene homolog 1 -3.78119
PPP6R1 protein phosphatase 6, regulatory subunit 1 -3.74808
UQCRC1 ubiquinol-cytochrome c reductase core protein I -3.7133
DGAT1 diacylglycerol O-acyltransferase 1 -3.69625
HSPD1 heat shock 60kDa protein 1 (chaperonin) -3.6748
OXA1L oxidase (cytochrome c) assembly 1-like -3.6681
GRN granulin -3.65015
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -3.63001
TKT transketolase -3.62725
LOC112694756 uncharaterized LOC112694756 -3.59691
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -3.59615
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -3.58647
ATP5F1B ATP synthase F1 subunit beta -3.58314
AATF apoptosis antagonizing transcription factor -3.55557
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -3.54316
CSK c-src tyrosine kinase -3.5393
MRPS2 mitochondrial ribosomal protein S2 -3.53871
ECH1 enoyl CoA hydratase 1, peroxisomal -3.51413
CAPNS1 calpain, small subunit 1 -3.51389
TECR trans-2,3-enoyl-CoA reductase -3.49685
LRP10 low density lipoprotein receptor-related protein 10 -3.48627
INTS3 integrator complex subunit 3 -3.47391
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -3.44582
HSPB1 heat shock 27kDa protein 1 -3.42347
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -3.39722
SH3D19 SH3 domain containing 19 -3.39719
CANT1 calcium activated nucleotidase 1 -3.385
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -3.37925
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -3.37735
RNF167 ring finger protein 167 -3.36719
NME2 NME/NM23 nucleoside diphosphate kinase 2 -3.35681
CDC25B cell division cycle 25B -3.34017
TM9SF2 transmembrane 9 superfamily member 2 -3.33682
AP2M1 adaptor-related protein complex 2, mu 1 subunit -3.30036
SLC25A46 solute carrier family 25, member 46 -3.29969
MRPL12 mitochondrial ribosomal protein L12 -3.29539
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -3.29238
STOML2 stomatin (EPB72)-like 2 -3.28848
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -3.27252
TFDP1 transcription factor Dp-1 -3.26987
AXIN1 axin 1 -3.24174
P4HB prolyl 4-hydroxylase, beta polypeptide -3.21849
ARFIP2 ADP-ribosylation factor interacting protein 2 -3.2166
PIH1D1 PIH1 domain containing 1 -3.20079
DCTN4 dynactin 4 (p62) -3.20048
PRMT5 protein arginine methyltransferase 5 -3.19201
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.18126
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -3.16355
HARS1 histidyl-tRNA synthetase 1 -3.13524
ATF5 activating transcription factor 5 -3.12882
DCTN3 dynactin 3 (p22) -3.12785
RPN1 ribophorin I -3.10777
VCP valosin containing protein -3.10578
ILK integrin-linked kinase -3.09243
C1QBP complement component 1, q subcomponent binding protein -3.06917
MAPK3 mitogen-activated protein kinase 3 -3.06585
ETHE1 ethylmalonic encephalopathy 1 -3.05556
ACOT7 acyl-CoA thioesterase 7 -3.04776
POLD4 polymerase (DNA-directed), delta 4, accessory subunit -3.0472
ATP5PD ATP synthase peripheral stalk subunit d -2.99803
PTOV1 prostate tumor overexpressed 1 -2.99054
CIRBP cold inducible RNA binding protein -2.98122
MPST mercaptopyruvate sulfurtransferase -2.97669
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.95355
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.92023
ATP5F1A ATP synthase F1 subunit alpha -2.90893
ATOX1 antioxidant 1 copper chaperone -2.888
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -2.8774
TRIM28 tripartite motif containing 28 -2.87409
TMSB10 thymosin beta 10 -2.86898
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.86522
PGM1 phosphoglucomutase 1 -2.85368
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.8495
TWF2 twinfilin actin binding protein 2 -2.84835
DTD1 D-tyrosyl-tRNA deacylase 1 -2.83643
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -2.82167
GUK1 guanylate kinase 1 -2.8209
HLA-G major histocompatibility complex, class I, G -2.81626
HLA-B major histocompatibility complex, class I, B -2.81065
DDB2 damage-specific DNA binding protein 2, 48kDa -2.79804
PARP1 poly (ADP-ribose) polymerase 1 -2.78873
GPS1 G protein pathway suppressor 1 -2.78346
TMBIM6 transmembrane BAX inhibitor motif containing 6 -2.77968
RABAC1 Rab acceptor 1 (prenylated) -2.77787
NUP85 nucleoporin 85kDa -2.75437
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.74629
DYNLRB1 dynein, light chain, roadblock-type 1 -2.7335
SPAG7 sperm associated antigen 7 -2.73293
TIMP1 TIMP metallopeptidase inhibitor 1 -2.73136
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -2.72708
MRPL24 mitochondrial ribosomal protein L24 -2.72678
MTA1 metastasis associated 1 -2.72595
USF2 upstream transcription factor 2, c-fos interacting -2.72579
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.72345
UBE2S ubiquitin-conjugating enzyme E2S -2.69353
MZT2B mitotic spindle organizing protein 2B -2.69338
LAGE3 L antigen family, member 3 -2.68891
NUDC nudC nuclear distribution protein -2.68186
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 -2.67815
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -2.67443
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.67175
JPT1 Jupiter microtubule associated homolog 1 -2.64402
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.63994
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -2.6329
SNF8 SNF8, ESCRT-II complex subunit -2.62924
PMF1-BGLAP PMF1-BGLAP readthrough -2.61501
TMEM147 transmembrane protein 147 -2.61417
GRHPR glyoxylate reductase/hydroxypyruvate reductase -2.60992
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 -2.60789
ZYX zyxin -2.60051
CCNI cyclin I -2.59738
MZT2A mitotic spindle organizing protein 2A -2.59587
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -2.59378
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -2.59167
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -2.58801
RBM42 RNA binding motif protein 42 -2.58266
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.57565
ASF1B anti-silencing function 1B histone chaperone -2.57293
WDR83OS WD repeat domain 83 opposite strand -2.56478
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) -2.5569
MGST3 microsomal glutathione S-transferase 3 -2.54441
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -2.53018
UBE3C ubiquitin protein ligase E3C -2.52382
ENTREP3 endosomal transmembrane epsin interactor 3 -2.52185
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.51089
PNPO pyridoxamine 5'-phosphate oxidase -2.50861
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.5056
TBCB tubulin folding cofactor B -2.50194
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -2.50042
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.49221
TSPAN3 tetraspanin 3 -2.49169
EVL Enah/Vasp-like -2.48435
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -2.4828
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.47484
RPL8 ribosomal protein L8 -2.47463
RPL18A ribosomal protein L18a -2.47017
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -2.46619
CLIC4 chloride intracellular channel 4 -2.46476
SNX17 sorting nexin 17 -2.46313
MRPL23 mitochondrial ribosomal protein L23 -2.45763
ITPRID2 ITPR interacting domain containing 2 -2.45413
FAM53C family with sequence similarity 53, member C -2.45117
LARP1 La ribonucleoprotein domain family, member 1 -2.45097
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.4502
MACIR macrophage immunometabolism regulator -2.4228
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -2.42189
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.42179
UCKL1 uridine-cytidine kinase 1-like 1 -2.41935
TBCA tubulin folding cofactor A -2.41295
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -2.41136
CIAO2B cytosolic iron-sulfur assembly component 2B -2.40907
UROS uroporphyrinogen III synthase -2.40429
MAGED2 melanoma antigen family D2 -2.40035
TMEM160 transmembrane protein 160 -2.39577
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -2.39128
ANO10 anoctamin 10 -2.39112
LASP1 LIM and SH3 protein 1 -2.38553
TCOF1 Treacher Collins-Franceschetti syndrome 1 -2.38468
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -2.3818
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -2.38129
KLC1 kinesin light chain 1 -2.37
KIF2C kinesin family member 2C -2.36655
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.36626
BOLA2B bolA family member 2B -2.36231
MGLL monoglyceride lipase -2.34339
ACTN4 actinin, alpha 4 -2.34109
ANKRD10 ankyrin repeat domain 10 -2.34072
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa -2.33744
RUVBL1 RuvB-like AAA ATPase 1 -2.33539
CH25H cholesterol 25-hydroxylase -2.3342
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -2.33191
ATP5F1D ATP synthase F1 subunit delta -2.32764
INF2 inverted formin, FH2 and WH2 domain containing -2.3251
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.32475
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -2.32456
CABIN1 calcineurin binding protein 1 -2.32085
SYNM synemin, intermediate filament protein -2.31912
NAP1L4 nucleosome assembly protein 1-like 4 -2.31642
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.31235
RUVBL2 RuvB-like AAA ATPase 2 -2.29944
MRPL30 mitochondrial ribosomal protein L30 -2.29792
RBM10 RNA binding motif protein 10 -2.29765
APEH acylaminoacyl-peptide hydrolase -2.29495
CRIP2 cysteine-rich protein 2 -2.29307
ACO2 aconitase 2, mitochondrial -2.28932
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.2893
SEPTIN10 septin 10 -2.28449
RPLP0 ribosomal protein, large, P0 -2.28372
HOXC6 homeobox C6 -2.27914
ZDHHC24 zinc finger, DHHC-type containing 24 -2.27753
RAN RAN, member RAS oncogene family -2.27722
S100A9 S100 calcium binding protein A9 -2.27189
NHP2 NHP2 ribonucleoprotein -2.27074
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -2.26796
COX7C cytochrome c oxidase subunit VIIc -2.26293
ALG3 ALG3, alpha-1,3- mannosyltransferase -2.26193
DCTD dCMP deaminase -2.25999
UBC ubiquitin C -2.25921
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -2.25889
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.25624
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -2.24701
OAZ1 ornithine decarboxylase antizyme 1 -2.24452
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -2.2425
HLA-C major histocompatibility complex, class I, C -2.24146
ENO1 enolase 1, (alpha) -2.23835
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -2.23502
ESYT1 extended synaptotagmin-like protein 1 -2.23261
SORBS3 sorbin and SH3 domain containing 3 -2.23065
HPS6 Hermansky-Pudlak syndrome 6 -2.2305
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -2.2304
RPLP1 ribosomal protein, large, P1 -2.22897
SNRPF small nuclear ribonucleoprotein polypeptide F -2.22782
MPDU1 mannose-P-dolichol utilization defect 1 -2.22765
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.227
ARPC5L actin related protein 2/3 complex, subunit 5-like -2.22614
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -2.22453
MICALL1 MICAL-like 1 -2.2233
FASTKD5 FAST kinase domains 5 -2.22251
WASF2 WAS protein family, member 2 -2.22071
CLTA clathrin, light chain A -2.22023
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 -2.21971
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.21388
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.21187
ATF4 activating transcription factor 4 -2.21067
H3-3B H3.3 histone B -2.21038
CUEDC2 CUE domain containing 2 -2.20816
PMP2 peripheral myelin protein 2 -2.20643
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) -2.20199
GIPC1 GIPC PDZ domain containing family, member 1 -2.19815
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 -2.19253
ITGA6 integrin, alpha 6 -2.18975
EMD emerin -2.18767
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.18593
SIRT2 sirtuin 2 -2.18087
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -2.18081
RNASEH2A ribonuclease H2, subunit A -2.17831
MDH1 malate dehydrogenase 1, NAD (soluble) -2.17691
MGMT O-6-methylguanine-DNA methyltransferase -2.17615
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 -2.17046
FURIN furin (paired basic amino acid cleaving enzyme) -2.16694
MRPS7 mitochondrial ribosomal protein S7 -2.16508
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) -2.16506
PRDX1 peroxiredoxin 1 -2.16315
PHB2 prohibitin 2 -2.16107
CAPN2 calpain 2, (m/II) large subunit -2.16087
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -2.15961
PGLS 6-phosphogluconolactonase -2.15893
PRRC2A proline-rich coiled-coil 2A -2.15862
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.15638
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.15587
SIRT7 sirtuin 7 -2.15533
FLNA filamin A, alpha -2.1499
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -2.14944
NCAPD2 non-SMC condensin I complex, subunit D2 -2.14335
DCTN2 dynactin 2 (p50) -2.14176
S100A4 S100 calcium binding protein A4 -2.13972
GYS1 glycogen synthase 1 (muscle) -2.13886
R3HCC1 R3H domain and coiled-coil containing 1 -2.13799
PARP4 poly (ADP-ribose) polymerase family, member 4 -2.13792
COX5B cytochrome c oxidase subunit Vb -2.13727
IGBP1 immunoglobulin (CD79A) binding protein 1 -2.13619
AVPI1 arginine vasopressin-induced 1 -2.13419
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.13128
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.12429
PACS2 phosphofurin acidic cluster sorting protein 2 -2.11868
WDR76 WD repeat domain 76 -2.1138
REEP4 receptor accessory protein 4 -2.11363
MT1H metallothionein 1H -2.11281
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -2.10956
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -2.1088
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -2.10227
CLINT1 clathrin interactor 1 -2.10172
SNRPA small nuclear ribonucleoprotein polypeptide A -2.09861
RPL30 ribosomal protein L30 -2.09795
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -2.09706
SLIRP SRA stem-loop interacting RNA binding protein -2.09677
UBE2M ubiquitin-conjugating enzyme E2M -2.09321
RPS9 ribosomal protein S9 -2.09155
CLTB clathrin, light chain B -2.08688
RNF187 ring finger protein 187 -2.0868
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.07776
RPL27A ribosomal protein L27a -2.07591
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.07404
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -2.07294
CTSG cathepsin G -2.07266
GRWD1 glutamate-rich WD repeat containing 1 -2.07132
TOP6BL TOP6B like initiator of meiotic double strand breaks -2.06797
TBC1D10B TBC1 domain family, member 10B -2.06744
CARM1 coactivator-associated arginine methyltransferase 1 -2.06571
EIF3K eukaryotic translation initiation factor 3, subunit K -2.06428
TUBB4B tubulin, beta 4B class IVb -2.06373
PIEZO1 piezo-type mechanosensitive ion channel component 1 -2.06251
GSTP1 glutathione S-transferase pi 1 -2.06025
DAD1 defender against cell death 1 -2.0581
CHMP6 charged multivesicular body protein 6 -2.05553
DEAF1 DEAF1 transcription factor -2.05544
PRCC papillary renal cell carcinoma (translocation-associated) -2.05282
H1-10 H1.10 linker histone -2.04465
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -2.03949
COX7B cytochrome c oxidase subunit VIIb -2.03876
MKI67 marker of proliferation Ki-67 -2.0377
GOLPH3 golgi phosphoprotein 3 (coat-protein) -2.03734
SQOR sulfide quinone oxidoreductase -2.03427
ARGLU1 arginine and glutamate rich 1 -2.0321
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.03016
DOLK dolichol kinase -2.02915
LRRC41 leucine rich repeat containing 41 -2.02872
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.02747
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -2.02649
CALR calreticulin -2.02127
PRMT1 protein arginine methyltransferase 1 -2.0212
F8A2 coagulation factor VIII-associated 2 -2.01755
PRCP prolylcarboxypeptidase (angiotensinase C) -2.01592
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 -2.01474
EIF4A3 eukaryotic translation initiation factor 4A3 -2.01246
FKBP5 FK506 binding protein 5 -2.01182
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.00882
MID1IP1 MID1 interacting protein 1 -2.00656
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I -2.00215