CRCGN016_MCF10A.WT.HP_24H:A03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:A03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 4.22025
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 3.70975
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.68797
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 3.32493
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 3.30575
TLCD3A TLC domain containing 3A 3.28581
PDLIM1 PDZ and LIM domain 1 3.01182
OLFML2B olfactomedin-like 2B 2.98814
CGRRF1 cell growth regulator with ring finger domain 1 2.1217

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -4.93955
S100A4 S100 calcium binding protein A4 -4.50297
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.78337
COG7 component of oligomeric golgi complex 7 -3.35862
TRAP1 TNF receptor-associated protein 1 -3.13841
ZNF274 zinc finger protein 274 -2.9067
BASP1 brain abundant, membrane attached signal protein 1 -2.65202
TCTA T-cell leukemia translocation altered -2.61209
TIMP1 TIMP metallopeptidase inhibitor 1 -2.54414
DYNLT3 dynein, light chain, Tctex-type 3 -2.51987
BPHL biphenyl hydrolase-like (serine hydrolase) -2.51884
ANXA2 annexin A2 -2.3898
ADAT1 adenosine deaminase, tRNA-specific 1 -2.35083
TRIM56 tripartite motif containing 56 -2.28194
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.25062
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.14382
LPXN leupaxin -2.12897
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.04847
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.03823
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -2.03447
KDM3A lysine (K)-specific demethylase 3A -2.01964