CRCGN016_MCF10A.WT.HP_24H:A04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

36 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:A04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 9.76427
CDCA4 cell division cycle associated 4 5.39294
TSEN2 TSEN2 tRNA splicing endonuclease subunit 4.41177
ADRB2 adrenoceptor beta 2, surface 3.40883
PDLIM1 PDZ and LIM domain 1 2.62277
SPAG4 sperm associated antigen 4 2.62113
COPS5 COP9 signalosome subunit 5 2.62063
HYOU1 hypoxia up-regulated 1 2.57661
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.54367
F13A1 coagulation factor XIII, A1 polypeptide 2.51229
RTN2 reticulon 2 2.47451
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.45816
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 2.24377
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.21189
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.19758
UBXN2B UBX domain protein 2B 2.1495
STAMBP STAM binding protein 2.03174
UBE2O ubiquitin-conjugating enzyme E2O 2.02014
TLCD3A TLC domain containing 3A 2.01982

decreased expression

Symbol Name Standardized Value
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -4.23072
FAIM Fas apoptotic inhibitory molecule -3.39418
RXYLT1 ribitol xylosyltransferase 1 -3.35613
SPRED2 sprouty-related, EVH1 domain containing 2 -3.11448
MSMO1 methylsterol monooxygenase 1 -2.99394
FPGS folylpolyglutamate synthase -2.84963
NPDC1 neural proliferation, differentiation and control, 1 -2.50383
HLA-A major histocompatibility complex, class I, A -2.4696
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) -2.3807
NUSAP1 nucleolar and spindle associated protein 1 -2.34794
ASCC1 activating signal cointegrator 1 complex subunit 1 -2.27232
KRT14 keratin 14, type I -2.25969
ZNF189 zinc finger protein 189 -2.1333
RHOH ras homolog family member H -2.13268
DSG2 desmoglein 2 -2.13152
CSRNP3 cysteine-serine-rich nuclear protein 3 -2.04078
MELK maternal embryonic leucine zipper kinase -2.03265