| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,2',3,5',6-pentachloro-1,1'-biphenyl 10.9 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:A09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MSRA | methionine sulfoxide reductase A | 5.23255 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 5.21969 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 4.9149 |
| COMP | cartilage oligomeric matrix protein | 4.6675 |
| NOSIP | nitric oxide synthase interacting protein | 4.16635 |
| MTA2 | metastasis associated 1 family, member 2 | 3.7748 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.72027 |
| NUTF2 | nuclear transport factor 2 | 3.503 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 3.48633 |
| FAT1 | FAT atypical cadherin 1 | 3.47965 |
| AGR2 | anterior gradient 2 | 3.4684 |
| MOK | MOK protein kinase | 3.3665 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 3.0743 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.01688 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 2.9733 |
| MDM4 | MDM4, p53 regulator | 2.9177 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 2.89552 |
| RBBP5 | retinoblastoma binding protein 5 | 2.8927 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 2.8523 |
| PRPF39 | pre-mRNA processing factor 39 | 2.7893 |
| TSPAN14 | tetraspanin 14 | 2.68505 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 2.6173 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.6095 |
| PLSCR3 | phospholipid scramblase 3 | 2.6021 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 2.47593 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 2.47445 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) | 2.3829 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 2.24975 |
| CDC42SE1 | CDC42 small effector 1 | 2.14885 |
| TSPYL4 | TSPY-like 4 | 2.13655 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.116 |
| WDR43 | WD repeat domain 43 | 2.11155 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 2.0944 |
| LETM1 | leucine zipper-EF-hand containing transmembrane protein 1 | 2.09355 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 2.06212 |
| AKTIP | AKT interacting protein | 2.05935 |
| ADRB2 | adrenoceptor beta 2, surface | 2.02385 |
| ODF2 | outer dense fiber of sperm tails 2 | 2.0135 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | 2.00055 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -5.49005 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.261 |
| HMG20B | high mobility group 20B | -4.383 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.9913 |
| THAP11 | THAP domain containing 11 | -3.6246 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.48095 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -3.46835 |
| GDF15 | growth differentiation factor 15 | -3.3988 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -3.1736 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.5661 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -2.5605 |
| HMOX2 | heme oxygenase 2 | -2.54822 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -2.47165 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -2.41645 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -2.39517 |
| TMEM186 | transmembrane protein 186 | -2.37355 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) | -2.18268 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -2.152 |
| CDC37 | cell division cycle 37 | -2.0898 |
| PCDH8 | protocadherin 8 | -2.0677 |
| RIC8A | RIC8 guanine nucleotide exchange factor A | -2.02945 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -2.0186 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 | -2.0175 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -2.014 |
| KCTD13 | potassium channel tetramerization domain containing 13 | -2.01117 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N | -2.00912 |
| ZNF571 | zinc finger protein 571 | -2.00145 |
