CRCGN016_MCF10A.WT.HP_24H:A10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-benzyl 2-butyl phthalate 101.51 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:A10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 4.41266
PEX11A peroxisomal biogenesis factor 11 alpha 4.15248
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 4.00053
OLFML2B olfactomedin-like 2B 2.81551
CDK19 cyclin-dependent kinase 19 2.76923
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.3202
PIH1D1 PIH1 domain containing 1 2.29526
PDIA5 protein disulfide isomerase family A, member 5 2.13982
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.07308

decreased expression

Symbol Name Standardized Value
CCDC86 coiled-coil domain containing 86 -4.99545
FBXO21 F-box protein 21 -2.89355
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.75608
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.72036
STXBP2 syntaxin binding protein 2 -2.58091
CORO1A coronin, actin binding protein, 1A -2.47814
BPHL biphenyl hydrolase-like (serine hydrolase) -2.40647
TOMM70 translocase of outer mitochondrial membrane 70 -2.39208
RIN3 Ras and Rab interactor 3 -2.10731
TRAP1 TNF receptor-associated protein 1 -2.05394
ALOX5 arachidonate 5-lipoxygenase -2.02899
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa -2.00007