CRCGN016_MCF10A.WT.HP_24H:A11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-benzyl 2-butyl phthalate 33.84 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

71 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:A11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.4728
FGFR4 fibroblast growth factor receptor 4 4.16607
DHRS2 dehydrogenase/reductase (SDR family) member 2 3.41683
ACAA1 acetyl-CoA acyltransferase 1 3.15417
COMP cartilage oligomeric matrix protein 3.00865
DPY19L1 dpy-19-like 1 (C. elegans) 2.61976
SFTPD surfactant protein D 2.44108
MOK MOK protein kinase 2.38655
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2.32384
TUBB4B tubulin, beta 4B class IVb 2.3089
AGR2 anterior gradient 2 2.28892
PTBP1 polypyrimidine tract binding protein 1 2.21839
CERS2 ceramide synthase 2 2.2052
SRSF8 serine/arginine-rich splicing factor 8 2.18637
TLCD3A TLC domain containing 3A 2.11778
SYNGAP1 synaptic Ras GTPase activating protein 1 2.09585
ATP13A1 ATPase type 13A1 2.06222
BRMS1L breast cancer metastasis-suppressor 1-like 2.05749
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 2.03628
GSTZ1 glutathione S-transferase zeta 1 2.03065
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 2.01125

decreased expression

Symbol Name Standardized Value
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.57024
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.22141
GDF15 growth differentiation factor 15 -4.82796
LDHD lactate dehydrogenase D -4.77703
CD58 CD58 molecule -4.08531
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -3.32509
ARID4A AT rich interactive domain 4A (RBP1-like) -3.31105
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -3.16612
RPS5 ribosomal protein S5 -2.92968
COG5 component of oligomeric golgi complex 5 -2.75991
VDAC1 voltage-dependent anion channel 1 -2.66524
IFRD1 interferon-related developmental regulator 1 -2.6629
ARHGAP15 Rho GTPase activating protein 15 -2.60422
APOO apolipoprotein O -2.57785
BPHL biphenyl hydrolase-like (serine hydrolase) -2.56901
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -2.5128
KRABD4 KRAB domain containing 4 -2.47033
DOCK2 dedicator of cytokinesis 2 -2.43293
ACO2 aconitase 2, mitochondrial -2.42869
RNF144A ring finger protein 144A -2.40318
ZFAND1 zinc finger, AN1-type domain 1 -2.36478
LAMB1 laminin, beta 1 -2.34897
CRYZL1 crystallin, zeta (quinone reductase)-like 1 -2.34321
LRRN3 leucine rich repeat neuronal 3 -2.33293
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -2.32865
PMPCB peptidase (mitochondrial processing) beta -2.32543
NFU1 NFU1 iron-sulfur cluster scaffold -2.28995
RNF113A ring finger protein 113A -2.2731
ZNF529 zinc finger protein 529 -2.25899
STRA6 stimulated by retinoic acid 6 -2.24638
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.22498
NID2 nidogen 2 (osteonidogen) -2.21516
ITGB1BP1 integrin beta 1 binding protein 1 -2.21482
THEMIS2 thymocyte selection associated family member 2 -2.18533
NIPSNAP3B nipsnap homolog 3B (C. elegans) -2.16937
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 -2.16397
POPDC2 popeye domain containing 2 -2.15467
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -2.13529
BEX4 brain expressed, X-linked 4 -2.11024
IFNA7 interferon, alpha 7 -2.0861
TENT4A terminal nucleotidyltransferase 4A -2.08317
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -2.06476
ZNHIT6 zinc finger, HIT-type containing 6 -2.05771
L1TD1 LINE-1 type transposase domain containing 1 -2.05149
ATP5PB ATP synthase peripheral stalk-membrane subunit b -2.04441
RNF186 ring finger protein 186 -2.03289
CFDP1 craniofacial development protein 1 -2.02916
ZNF277 zinc finger protein 277 -2.02022
LOC128125814 uncharacterized LOC128125814 -2.01585
MOAP1 modulator of apoptosis 1 -2.00476