| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-benzyl 2-butyl phthalate 11.28 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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86 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:A12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CNPY3 | canopy FGF signaling regulator 3 | 5.30338 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 5.03693 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 5.02296 |
| STAP2 | signal transducing adaptor family member 2 | 4.95792 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.91585 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 4.85401 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 4.66163 |
| SPAG4 | sperm associated antigen 4 | 4.59112 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 4.55317 |
| OLFML2B | olfactomedin-like 2B | 3.71888 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 3.49584 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.24986 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 2.96641 |
| NUTF2 | nuclear transport factor 2 | 2.87134 |
| MTFR1 | mitochondrial fission regulator 1 | 2.74548 |
| STAMBP | STAM binding protein | 2.6264 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.56212 |
| MDM4 | MDM4, p53 regulator | 2.55445 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 2.52881 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 2.50336 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 2.48725 |
| TMPRSS11D | transmembrane protease, serine 11D | 2.37946 |
| RLIM | ring finger protein, LIM domain interacting | 2.32932 |
| SIRT3 | sirtuin 3 | 2.32585 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | 2.32239 |
| RBBP5 | retinoblastoma binding protein 5 | 2.27957 |
| TXNL4B | thioredoxin-like 4B | 2.26512 |
| AGR2 | anterior gradient 2 | 2.25722 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 2.22198 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 2.20061 |
| HDAC2 | histone deacetylase 2 | 2.19663 |
| HOXC6 | homeobox C6 | 2.18871 |
| MTA2 | metastasis associated 1 family, member 2 | 2.15795 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component | 2.11986 |
| POMK | protein-O-mannose kinase | 2.11761 |
| CTSZ | cathepsin Z | 2.11204 |
| IFITM3 | interferon induced transmembrane protein 3 | 2.11071 |
| IFITM2 | interferon induced transmembrane protein 2 | 2.07015 |
| TMEM101 | transmembrane protein 101 | 2.04382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COG7 | component of oligomeric golgi complex 7 | -5.86742 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.19798 |
| GDF15 | growth differentiation factor 15 | -4.81989 |
| CCNB1 | cyclin B1 | -4.7477 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.47453 |
| MELK | maternal embryonic leucine zipper kinase | -3.085 |
| HAGH | hydroxyacylglutathione hydrolase | -2.89173 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -2.85786 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | -2.76603 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -2.76268 |
| DHPS | deoxyhypusine synthase | -2.70555 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.67149 |
| HIRIP3 | HIRA interacting protein 3 | -2.66732 |
| ZNF500 | zinc finger protein 500 | -2.64876 |
| BFAR | bifunctional apoptosis regulator | -2.57983 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 | -2.34596 |
| STXBP2 | syntaxin binding protein 2 | -2.2985 |
| RAB33A | RAB33A, member RAS oncogene family | -2.29577 |
| ZNF263 | zinc finger protein 263 | -2.26041 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 | -2.25274 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -2.23183 |
| CBLIF | cobalamin binding intrinsic factor | -2.22899 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -2.17637 |
| METTL22 | methyltransferase like 22 | -2.16989 |
| SCAMP5 | secretory carrier membrane protein 5 | -2.16187 |
| PCDHA9 | protocadherin alpha 9 | -2.147 |
| POLR3E | polymerase (RNA) III (DNA directed) polypeptide E (80kD) | -2.13731 |
| MT1X | metallothionein 1X | -2.13714 |
| TRIM36 | tripartite motif containing 36 | -2.12016 |
| SOX3 | SRY (sex determining region Y)-box 3 | -2.10353 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -2.0879 |
| ATP4B | ATPase, H+/K+ exchanging, beta polypeptide | -2.08082 |
| LIPF | lipase, gastric | -2.07946 |
| METTL25B | methyltransferase like 25B | -2.06656 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 | -2.06541 |
| BEX4 | brain expressed, X-linked 4 | -2.0537 |
| KCTD13 | potassium channel tetramerization domain containing 13 | -2.05026 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.04974 |
| TMEM268 | transmembrane protein 268 | -2.04861 |
| PRKCQ | protein kinase C, theta | -2.04531 |
| BOLA1 | bolA family member 1 | -2.04253 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -2.03552 |
| GSPT2 | G1 to S phase transition 2 | -2.02308 |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit | -2.01971 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -2.0072 |
| SH3GL2 | SH3-domain GRB2-like 2 | -2.00238 |
| TOX3 | TOX high mobility group box family member 3 | -2.00228 |