CRCGN016_MCF10A.WT.HP_24H:A13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,2',4,4',5,5'-hexachloro-1,1'-biphenyl 98.52 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:A13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.646
TIAM1 T-cell lymphoma invasion and metastasis 1 2.71738
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.43242
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.30557
MRPS17 mitochondrial ribosomal protein S17 2.01734

decreased expression

Symbol Name Standardized Value
ARID4B AT rich interactive domain 4B (RBP1-like) -5.69828
DCK deoxycytidine kinase -4.37176
LYPLA1 lysophospholipase I -3.76473
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.28603
OXA1L oxidase (cytochrome c) assembly 1-like -3.27347
RALGDS ral guanine nucleotide dissociation stimulator -3.18544
TUBB6 tubulin, beta 6 class V -3.08865
TIMP1 TIMP metallopeptidase inhibitor 1 -2.58329
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.24676
HOXA5 homeobox A5 -2.23281
POLD4 polymerase (DNA-directed), delta 4, accessory subunit -2.20252
STXBP2 syntaxin binding protein 2 -2.14104