CRCGN016_MCF10A.WT.HP_24H:A14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,2',4,4',5,5'-hexachloro-1,1'-biphenyl 32.84 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:A14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 5.53183
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 4.71996
SATB1 SATB homeobox 1 3.00268
ZW10 zw10 kinetochore protein 2.94727
TMEM109 transmembrane protein 109 2.35073
PRR7 proline rich 7 (synaptic) 2.3286
MOK MOK protein kinase 2.20925

decreased expression

Symbol Name Standardized Value
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.31031
VAT1 vesicle amine transport 1 -3.73386
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.1257
BPHL biphenyl hydrolase-like (serine hydrolase) -2.62834
MSMO1 methylsterol monooxygenase 1 -2.2586
ARID4B AT rich interactive domain 4B (RBP1-like) -2.14489
HOXA5 homeobox A5 -2.08763