CRCGN016_MCF10A.WT.HP_24H:A21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-hydroxy-2-acetylamino?fluorene 11.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

987 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:A21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 9.43503
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 8.46852
LRP10 low density lipoprotein receptor-related protein 10 6.96967
RGS2 regulator of G-protein signaling 2 6.62037
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 6.40656
WIF1 WNT inhibitory factor 1 6.08185
FHL2 four and a half LIM domains 2 6.07592
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 6.02557
DUSP14 dual specificity phosphatase 14 5.70388
NOTCH1 notch 1 5.58345
INPP1 inositol polyphosphate-1-phosphatase 5.3828
ADRB2 adrenoceptor beta 2, surface 5.37793
BLCAP bladder cancer associated protein 5.33985
AGR2 anterior gradient 2 5.31224
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 5.02172
MICALL1 MICAL-like 1 4.91156
CCDC92 coiled-coil domain containing 92 4.8883
TXLNA taxilin alpha 4.71135
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.64783
STAMBP STAM binding protein 4.56428
PHLDA3 pleckstrin homology-like domain, family A, member 3 4.5355
FDXR ferredoxin reductase 4.41362
AARS1 alanyl-tRNA synthetase 1 4.40852
DDB2 damage-specific DNA binding protein 2, 48kDa 4.40514
FAT1 FAT atypical cadherin 1 4.39478
ASNS asparagine synthetase (glutamine-hydrolyzing) 4.25994
INTS3 integrator complex subunit 3 4.13219
RALGDS ral guanine nucleotide dissociation stimulator 4.11394
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 4.10988
SKIC2 SKI2 subunit of superkiller complex 4.10983
CARS1 cysteinyl-tRNA synthetase 1 4.06108
EPS8L2 EPS8-like 2 4.03625
ZCCHC8 zinc finger, CCHC domain containing 8 3.92274
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.90007
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 3.88757
GARS1 glycyl-tRNA synthetase 1 3.87686
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 3.87557
ZMAT3 zinc finger, matrin-type 3 3.87086
SYNE2 spectrin repeat containing, nuclear envelope 2 3.8265
TUFT1 tuftelin 1 3.82141
PYCR1 pyrroline-5-carboxylate reductase 1 3.81474
AEN apoptosis enhancing nuclease 3.75617
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 3.74662
KPTN kaptin (actin binding protein) 3.71696
TMEM40 transmembrane protein 40 3.69833
PSAT1 phosphoserine aminotransferase 1 3.69164
YARS1 tyrosyl-tRNA synthetase 1 3.67805
SPG11 spastic paraplegia 11 (autosomal recessive) 3.67296
ACAA1 acetyl-CoA acyltransferase 1 3.67154
CALCOCO1 calcium binding and coiled-coil domain 1 3.66814
GCC1 GRIP and coiled-coil domain containing 1 3.66278
BAX BCL2-associated X protein 3.66083
FYN FYN proto-oncogene, Src family tyrosine kinase 3.64749
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 3.63811
AMOTL2 angiomotin like 2 3.62365
TMEM131 transmembrane protein 131 3.59149
MUC13 mucin 13, cell surface associated 3.51935
MVP major vault protein 3.50847
SLC67A1 solute carrier family 67 member 1 3.50728
PYCARD PYD and CARD domain containing 3.47952
ITPKC inositol-trisphosphate 3-kinase C 3.47693
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 3.45803
KLHL21 kelch-like family member 21 3.45657
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.44344
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 3.42778
COG4 component of oligomeric golgi complex 4 3.42392
WHRN whirlin 3.40756
TIGAR TP53 induced glycolysis regulatory phosphatase 3.40023
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.38703
RETREG2 reticulophagy regulator family member 2 3.37975
COMP cartilage oligomeric matrix protein 3.37194
RABGGTA Rab geranylgeranyltransferase, alpha subunit 3.36089
VPS9D1 VPS9 domain containing 1 3.35095
ATF4 activating transcription factor 4 3.3509
MARS1 methionyl-tRNA synthetase 1 3.34312
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 3.33435
EPHA2 EPH receptor A2 3.3186
RAB11FIP5 RAB11 family interacting protein 5 (class I) 3.30482
OXSR1 oxidative stress responsive 1 3.30063
RNF220 ring finger protein 220 3.29153
BDKRB2 bradykinin receptor B2 3.28114
TRIB3 tribbles pseudokinase 3 3.27197
CEMIP2 cell migration inducing hyaluronidase 2 3.27133
ABHD4 abhydrolase domain containing 4 3.26565
PHGDH phosphoglycerate dehydrogenase 3.26297
MAP6D1 MAP6 domain containing 1 3.24444
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 3.22785
CHIC2 cysteine-rich hydrophobic domain 2 3.21791
CNKSR1 connector enhancer of kinase suppressor of Ras 1 3.21366
CXCR4 chemokine (C-X-C motif) receptor 4 3.20969
ZDHHC11B zinc finger, DHHC-type containing 11B 3.20447
PGPEP1 pyroglutamyl-peptidase I 3.20189
CTC1 CTS telomere maintenance complex component 1 3.18867
MARK4 MAP/microtubule affinity-regulating kinase 4 3.18576
RAB5B RAB5B, member RAS oncogene family 3.1844
DAPL1 death associated protein-like 1 3.18006
METTL25B methyltransferase like 25B 3.1738
LOC128125814 uncharacterized LOC128125814 3.16991
TMEM94 transmembrane protein 94 3.14035
PLA2G15 phospholipase A2, group XV 3.12438
TP53I3 tumor protein p53 inducible protein 3 3.1232
KRT34 keratin 34, type I 3.12274
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 3.10459
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.09332
SLC30A1 solute carrier family 30 (zinc transporter), member 1 3.09255
XPOT exportin, tRNA 3.09085
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 3.08674
ORAI3 ORAI calcium release-activated calcium modulator 3 3.08345
KDM5A lysine (K)-specific demethylase 5A 3.07761
PHF21A PHD finger protein 21A 3.05582
SIN3B SIN3 transcription regulator family member B 3.04963
NLRX1 NLR family member X1 3.04892
HMOX1 heme oxygenase 1 3.04729
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.04075
TXNRD1 thioredoxin reductase 1 3.04052
ATG9A autophagy related 9A 3.03913
RPS27L ribosomal protein S27-like 3.02628
COPG1 coatomer protein complex, subunit gamma 1 3.01555
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.99646
SH3BP4 SH3-domain binding protein 4 2.99535
RABAC1 Rab acceptor 1 (prenylated) 2.99279
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.98248
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 2.97412
CNPPD1 cyclin Pas1/PHO80 domain containing 1 2.97092
TES testin LIM domain protein 2.96813
SESN1 sestrin 1 2.968
THBS3 thrombospondin 3 2.96458
TERF2IP telomeric repeat binding factor 2, interacting protein 2.94807
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 2.94364
PLK3 polo-like kinase 3 2.94113
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 2.93872
SPATA20 spermatogenesis associated 20 2.93774
CANT1 calcium activated nucleotidase 1 2.93611
STC2 stanniocalcin 2 2.9346
SLC16A6 solute carrier family 16, member 6 2.92958
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.92037
RTF2 replication termination factor 2 2.91968
MOK MOK protein kinase 2.91263
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.9113
TOM1 target of myb1 (chicken) 2.90779
POMT1 protein-O-mannosyltransferase 1 2.90048
FES FES proto-oncogene, tyrosine kinase 2.88967
TRAPPC12 trafficking protein particle complex 12 2.87997
AVPI1 arginine vasopressin-induced 1 2.87724
MAPK13 mitogen-activated protein kinase 13 2.87341
GAS6 growth arrest-specific 6 2.87229
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.86688
CYB5R1 cytochrome b5 reductase 1 2.86258
PPCDC phosphopantothenoylcysteine decarboxylase 2.85113
LOC102724428 serine/threonine-protein kinase SIK1 2.8504
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.8304
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.81366
VSIG2 V-set and immunoglobulin domain containing 2 2.81254
NUPR1 nuclear protein, transcriptional regulator, 1 2.81082
NADSYN1 NAD synthetase 1 2.79116
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.77909
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.77815
APH1A APH1A gamma secretase subunit 2.7762
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.77541
CDK5RAP3 CDK5 regulatory subunit associated protein 3 2.77532
RAP1GAP2 RAP1 GTPase activating protein 2 2.77306
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.77218
PPCS phosphopantothenoylcysteine synthetase 2.7679
TSC1 tuberous sclerosis 1 2.74562
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.74499
XPC xeroderma pigmentosum, complementation group C 2.73615
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 2.7295
ADCY7 adenylate cyclase 7 2.72722
NXPE3 neurexophilin and PC-esterase domain family, member 3 2.72161
CASZ1 castor zinc finger 1 2.71394
SARS1 seryl-tRNA synthetase 1 2.71205
CHMP4B charged multivesicular body protein 4B 2.71052
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 2.69438
SLC75A1 solute carrier family 75 member 1 2.69434
CPT1B carnitine palmitoyltransferase 1B (muscle) 2.68318
WDR11 WD repeat domain 11 2.66855
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.66499
VAT1 vesicle amine transport 1 2.66485
FAM50A family with sequence similarity 50, member A 2.65564
NBEAL2 neurobeachin-like 2 2.65516
PDLIM2 PDZ and LIM domain 2 (mystique) 2.65036
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 2.64209
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.64086
VLDLR very low density lipoprotein receptor 2.6378
PSG5 pregnancy specific beta-1-glycoprotein 5 2.63471
STXBP2 syntaxin binding protein 2 2.63012
IST1 increased sodium tolerance 1 homolog (yeast) 2.62796
ISG15 ISG15 ubiquitin-like modifier 2.62516
KRT6A keratin 6A, type II 2.62434
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.62193
DNMBP dynamin binding protein 2.61689
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.61674
GRN granulin 2.6138
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.60683
MINDY1 MINDY lysine 48 deubiquitinase 1 2.5934
TICAM1 toll-like receptor adaptor molecule 1 2.59035
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 2.58432
GSE1 Gse1 coiled-coil protein 2.58309
PARP12 poly (ADP-ribose) polymerase family, member 12 2.58003
STXBP1 syntaxin binding protein 1 2.57746
LMTK1 lemur tail kinase 1 2.57663
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 2.56711
YBX3 Y box binding protein 3 2.56627
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 2.56575
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.5631
ERCC6 excision repair cross-complementation group 6 2.55748
STAT2 signal transducer and activator of transcription 2, 113kDa 2.5566
TBX21 T-box 21 2.54924
LRRC47 leucine rich repeat containing 47 2.54757
NUAK2 NUAK family, SNF1-like kinase, 2 2.54097
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 2.53771
TRIM8 tripartite motif containing 8 2.53508
CSTA cystatin A (stefin A) 2.53025
RBMS2 RNA binding motif, single stranded interacting protein 2 2.52692
CMTR1 cap methyltransferase 1 2.52637
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 2.52386
SUGCT succinyl-CoA:glutarate-CoA transferase 2.52349
TRIP12 thyroid hormone receptor interactor 12 2.52069
RAP1GAP RAP1 GTPase activating protein 2.52042
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.51648
TMEM127 transmembrane protein 127 2.5152
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2.51185
UBE4A ubiquitination factor E4A 2.5089
NELFA negative elongation factor complex member A 2.49723
INPPL1 inositol polyphosphate phosphatase-like 1 2.49569
METTL22 methyltransferase like 22 2.48761
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 2.48379
GIPC1 GIPC PDZ domain containing family, member 1 2.48336
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.47827
CRY2 cryptochrome circadian clock 2 2.47756
KLHDC4 kelch domain containing 4 2.47512
NISCH nischarin 2.47419
STARD5 StAR-related lipid transfer (START) domain containing 5 2.47236
KDM4A lysine (K)-specific demethylase 4A 2.47161
PSEN1 presenilin 1 2.46753
GOLGA8N golgin A8 family, member N 2.4672
TTC4 tetratricopeptide repeat domain 4 2.46702
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 2.4662
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 2.46437
TOB1 transducer of ERBB2, 1 2.45958
FGF9 fibroblast growth factor 9 2.45395
DCTN1 dynactin 1 2.44998
PRSS8 protease, serine, 8 2.44079
IER5 immediate early response 5 2.43798
CLBA1 clathrin binding box of aftiphilin containing 1 2.43606
ELAC2 elaC ribonuclease Z 2 2.43409
IRF6 interferon regulatory factor 6 2.43185
CAMTA2 calmodulin binding transcription activator 2 2.43033
TRIM16 tripartite motif containing 16 2.42994
ANO10 anoctamin 10 2.42415
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.42086
DENND10 DENN domain containing 10 2.42013
WFS1 Wolfram syndrome 1 (wolframin) 2.4198
GPR87 G protein-coupled receptor 87 2.41842
MINDY3 MINDY lysine 48 deubiquitinase 3 2.417
NRBF2 nuclear receptor binding factor 2 2.41303
PLD2 phospholipase D2 2.41129
SMG5 SMG5 nonsense mediated mRNA decay factor 2.40751
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.40746
NCSTN nicastrin 2.40559
TRIT1 tRNA isopentenyltransferase 1 2.40499
TARS1 threonyl-tRNA synthetase 1 2.40252
IFRD1 interferon-related developmental regulator 1 2.40143
TMEM80 transmembrane protein 80 2.39701
TCEA2 transcription elongation factor A (SII), 2 2.39588
UFM1 ubiquitin-fold modifier 1 2.39096
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.39024
TPCN1 two pore segment channel 1 2.38922
CALCOCO2 calcium binding and coiled-coil domain 2 2.38921
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 2.38768
ATP5IF1 ATP synthase inhibitory factor subunit 1 2.38716
ZBED2 zinc finger, BED-type containing 2 2.38573
COL4A5 collagen, type IV, alpha 5 2.38511
RNF43 ring finger protein 43 2.38189
ZNF783 zinc finger family member 783 2.38161
ZNF197 zinc finger protein 197 2.37744
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 2.37622
FOSL2 FOS-like antigen 2 2.37583
LIMK2 LIM domain kinase 2 2.37493
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 2.37399
CTSZ cathepsin Z 2.37381
DNASE1L1 deoxyribonuclease I-like 1 2.36835
EML2 echinoderm microtubule associated protein like 2 2.36565
LRRC8D leucine rich repeat containing 8 family, member D 2.3624
ASCC3 activating signal cointegrator 1 complex subunit 3 2.36169
ADGRE5 adhesion G protein-coupled receptor E5 2.36033
BSDC1 BSD domain containing 1 2.35714
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 2.35516
FOXO4 forkhead box O4 2.35309
CDK18 cyclin-dependent kinase 18 2.34589
POMT2 protein-O-mannosyltransferase 2 2.34531
ATF3 activating transcription factor 3 2.33009
PINK1 PTEN induced putative kinase 1 2.3297
OSBPL2 oxysterol binding protein-like 2 2.32829
TFE3 transcription factor binding to IGHM enhancer 3 2.32807
GMPPA GDP-mannose pyrophosphorylase A 2.32606
HDLBP high density lipoprotein binding protein 2.32449
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.32428
TNIP1 TNFAIP3 interacting protein 1 2.32377
KATNIP katanin interacting protein 2.32367
TBX2 T-box 2 2.32188
IFI6 interferon, alpha-inducible protein 6 2.32141
STAP2 signal transducing adaptor family member 2 2.32079
ATXN2 ataxin 2 2.31975
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.31756
TRIM22 tripartite motif containing 22 2.31453
SMAD3 SMAD family member 3 2.31416
ULBP2 UL16 binding protein 2 2.31323
DDR1 discoidin domain receptor tyrosine kinase 1 2.31258
MISP mitotic spindle positioning 2.30991
MTX1 metaxin 1 2.30958
OSBPL9 oxysterol binding protein-like 9 2.30697
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.3025
SSH3 slingshot protein phosphatase 3 2.30227
EDF1 endothelial differentiation-related factor 1 2.30005
BBC3 BCL2 binding component 3 2.29676
RRAGC Ras-related GTP binding C 2.29428
NECAP1 NECAP endocytosis associated 1 2.29295
SPAG1 sperm associated antigen 1 2.29285
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.29245
CLCA2 chloride channel accessory 2 2.2923
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 2.28944
STK16 serine/threonine kinase 16 2.28913
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 2.28693
PTK6 protein tyrosine kinase 6 2.2867
MAPK3 mitogen-activated protein kinase 3 2.28548
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.28455
MAP3K9 mitogen-activated protein kinase kinase kinase 9 2.28423
TPPP3 tubulin polymerization-promoting protein family member 3 2.2761
LARP6 La ribonucleoprotein domain family, member 6 2.27476
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.27351
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.27348
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.27291
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.27221
ACTMAP actin maturation protease 2.26485
PSG6 pregnancy specific beta-1-glycoprotein 6 2.26449
NRDC nardilysin convertase 2.26446
ADAM17 ADAM metallopeptidase domain 17 2.26412
TGFA transforming growth factor, alpha 2.26364
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.26358
GBA1 glucosylceramidase beta 1 2.26294
DENND4B DENN/MADD domain containing 4B 2.26231
MX2 MX dynamin-like GTPase 2 2.26207
PAAF1 proteasomal ATPase-associated factor 1 2.2603
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.25773
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 2.25743
CLDN1 claudin 1 2.25719
MED13L mediator complex subunit 13-like 2.25577
SPEG SPEG complex locus 2.25064
TBC1D2 TBC1 domain family, member 2 2.24806
BTG1 B-cell translocation gene 1, anti-proliferative 2.24644
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 2.2464
TACC2 transforming, acidic coiled-coil containing protein 2 2.24501
NPC1 Niemann-Pick disease, type C1 2.24489
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.24414
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 2.2422
CADM1 cell adhesion molecule 1 2.24218
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.23496
SCD5 stearoyl-CoA desaturase 5 2.23459
RUSC2 RUN and SH3 domain containing 2 2.2344
TRIM31 tripartite motif containing 31 2.23197
SPINT2 serine peptidase inhibitor, Kunitz type, 2 2.22573
SPATA2L spermatogenesis associated 2-like 2.2257
CDC16 cell division cycle 16 2.22408
DUSP10 dual specificity phosphatase 10 2.22396
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.22041
ZBTB48 zinc finger and BTB domain containing 48 2.21786
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.21681
PROP1 PROP paired-like homeobox 1 2.21323
TMEM59 transmembrane protein 59 2.21104
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.20978
LOC114841035 uncharacterized LOC114841035 2.20624
TM9SF3 transmembrane 9 superfamily member 3 2.20394
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 2.20151
GABARAPL1 GABA(A) receptor-associated protein like 1 2.19553
YTHDC1 YTH domain containing 1 2.19214
SDK2 sidekick cell adhesion molecule 2 2.18951
TTLL3 tubulin tyrosine ligase-like family member 3 2.18816
LOXL1 lysyl oxidase-like 1 2.1869
SPI1 Spi-1 proto-oncogene 2.1858
COL9A2 collagen, type IX, alpha 2 2.18132
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 2.17923
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 2.17811
ANXA4 annexin A4 2.17789
FKRP fukutin related protein 2.17625
PPP4R1 protein phosphatase 4, regulatory subunit 1 2.1726
BABAM2 BRISC and BRCA1 A complex member 2 2.17194
EFHC1 EF-hand domain (C-terminal) containing 1 2.17087
NOP10 NOP10 ribonucleoprotein 2.17022
NMRK1 nicotinamide riboside kinase 1 2.16851
PLK2 polo-like kinase 2 2.16813
NARS1 asparaginyl-tRNA synthetase 1 2.16742
VILL villin-like 2.16654
IL17RA interleukin 17 receptor A 2.16225
SQSTM1 sequestosome 1 2.16188
CNTN2 contactin 2 (axonal) 2.16182
NCF2 neutrophil cytosolic factor 2 2.15947
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.15377
FBXO2 F-box protein 2 2.15356
LRRC41 leucine rich repeat containing 41 2.15271
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.15098
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 2.14757
BCL2L1 BCL2-like 1 2.14733
APOL6 apolipoprotein L, 6 2.14309
HDAC4 histone deacetylase 4 2.14242
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.13904
LOC128125822 uncharacterized LOC128125822 2.13852
CSRNP2 cysteine-serine-rich nuclear protein 2 2.13788
ZNF79 zinc finger protein 79 2.13693
OLFML2A olfactomedin-like 2A 2.13639
GPBP1L1 GC-rich promoter binding protein 1-like 1 2.13352
UBAP2 ubiquitin associated protein 2 2.13311
MYT1 myelin transcription factor 1 2.13254
THSD1 thrombospondin, type I, domain containing 1 2.1312
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.12823
BBS1 Bardet-Biedl syndrome 1 2.12519
PLEKHO2 pleckstrin homology domain containing, family O member 2 2.12314
KRT6B keratin 6B, type II 2.1229
MAN1B1 mannosidase, alpha, class 1B, member 1 2.12246
NAXD NAD(P)HX dehydratase 2.12142
FGF17 fibroblast growth factor 17 2.11978
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 2.11929
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 2.11684
LRRC36 leucine rich repeat containing 36 2.11484
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.11332
JMJD1C jumonji domain containing 1C 2.11144
UBTD1 ubiquitin domain containing 1 2.11101
NCBP3 nuclear cap binding subunit 3 2.1108
GAK cyclin G associated kinase 2.10845
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.10424
KRT5 keratin 5, type II 2.10289
KMT5B lysine methyltransferase 5B 2.10226
STK25 serine/threonine kinase 25 2.0964
RAB38 RAB38, member RAS oncogene family 2.09224
TBC1D3G TBC1 domain family member 3G 2.09078
CLTB clathrin, light chain B 2.08495
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 2.08434
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 2.08069
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.07767
ZNF212 zinc finger protein 212 2.07559
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.07168
JAG2 jagged 2 2.07004
PPL periplakin 2.06997
HBEGF heparin-binding EGF-like growth factor 2.06925
SCAF8 SR-related CTD-associated factor 8 2.06814
GRB10 growth factor receptor-bound protein 10 2.06757
CD7 CD7 molecule 2.06686
FAM246A family with sequence similarity 246 member A 2.06483
GPC1 glypican 1 2.0643
ARHGAP1 Rho GTPase activating protein 1 2.06401
NECTIN2 nectin cell adhesion molecule 2 2.06051
ARCN1 archain 1 2.06034
PNPLA6 patatin-like phospholipase domain containing 6 2.05456
MXRA5 matrix-remodelling associated 5 2.05334
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.05016
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 2.04925
ADGRG1 adhesion G protein-coupled receptor G1 2.04781
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.04629
EML3 echinoderm microtubule associated protein like 3 2.04628
SCRIB scribbled planar cell polarity protein 2.04374
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.04316
ARID3A AT rich interactive domain 3A (BRIGHT-like) 2.04213
OSR2 odd-skipped related transciption factor 2 2.03811
LOC122526780 uncharacterized LOC122526780 2.03565
THRAP3 thyroid hormone receptor associated protein 3 2.0354
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.03217
NPIPB5 nuclear pore complex interacting protein family, member B5 2.03151
HHAT hedgehog acyltransferase 2.03078
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.03033
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 2.02941
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.02898
PRAF2 PRA1 domain family, member 2 2.02598
MKRN1 makorin ring finger protein 1 2.02594
TMEM212 transmembrane protein 212 2.02323
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.02319
CDR2L cerebellar degeneration-related protein 2-like 2.02141
ANKZF1 ankyrin repeat and zinc finger domain containing 1 2.02068
FBXO42 F-box protein 42 2.02065
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.01764
DGKA diacylglycerol kinase, alpha 80kDa 2.01747
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.01661
SPAG7 sperm associated antigen 7 2.01558
HS1BP3 HCLS1 binding protein 3 2.0112
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 2.01035
PAMR1 peptidase domain containing associated with muscle regeneration 1 2.00908
TM2D1 TM2 domain containing 1 2.00733
ZNF592 zinc finger protein 592 2.00466
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.00422
HBA1 hemoglobin, alpha 1 2.0042
CDH22 cadherin 22, type 2 2.00373
DKK3 dickkopf WNT signaling pathway inhibitor 3 2.00219
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 2.00201
LAMB3 laminin, beta 3 2.00135

decreased expression

Symbol Name Standardized Value
UBE2C ubiquitin-conjugating enzyme E2C -10.0
CDC20 cell division cycle 20 -10.0
CDC45 cell division cycle 45 -9.49543
AURKB aurora kinase B -9.14331
PLK1 polo-like kinase 1 -9.1088
CCNB2 cyclin B2 -8.89518
KIF20A kinesin family member 20A -8.72243
LBR lamin B receptor -8.60691
STMN1 stathmin 1 -8.15998
CCNA2 cyclin A2 -7.77375
PSRC1 proline/serine-rich coiled-coil 1 -7.67547
KIF14 kinesin family member 14 -7.59648
CDK1 cyclin-dependent kinase 1 -7.16226
BIRC5 baculoviral IAP repeat containing 5 -7.13678
TOP2A topoisomerase (DNA) II alpha 170kDa -7.09534
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -6.76838
NCAPD2 non-SMC condensin I complex, subunit D2 -6.5029
DCK deoxycytidine kinase -6.34093
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -6.31675
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -6.28788
DEPDC1 DEP domain containing 1 -6.23524
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -6.02996
HSPA8 heat shock 70kDa protein 8 -5.99366
NUSAP1 nucleolar and spindle associated protein 1 -5.86965
SPC25 SPC25, NDC80 kinetochore complex component -5.76931
HMMR hyaluronan-mediated motility receptor (RHAMM) -5.58648
MCM3 minichromosome maintenance complex component 3 -5.5621
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -5.45429
KIF4A kinesin family member 4A -5.38963
HAT1 histone acetyltransferase 1 -5.37306
NT5DC2 5'-nucleotidase domain containing 2 -5.32715
KIF18B kinesin family member 18B -5.31751
NCAPH non-SMC condensin I complex, subunit H -5.27742
ATAD2 ATPase family, AAA domain containing 2 -5.26996
ASF1B anti-silencing function 1B histone chaperone -5.1601
FBXO5 F-box protein 5 -5.09257
MRPL19 mitochondrial ribosomal protein L19 -5.04166
KIF11 kinesin family member 11 -4.96326
CBR3 carbonyl reductase 3 -4.95765
CDCA3 cell division cycle associated 3 -4.93399
CENPA centromere protein A -4.86992
KIF15 kinesin family member 15 -4.86016
AURKA aurora kinase A -4.8508
RPA3 replication protein A3, 14kDa -4.83873
TPX2 TPX2, microtubule-associated -4.79274
NUP85 nucleoporin 85kDa -4.78441
PIMREG PICALM interacting mitotic regulator -4.72372
RFC2 replication factor C (activator 1) 2, 40kDa -4.70617
PARP2 poly (ADP-ribose) polymerase 2 -4.58737
CDKN3 cyclin-dependent kinase inhibitor 3 -4.56666
GMNN geminin, DNA replication inhibitor -4.56003
CCNB1 cyclin B1 -4.50732
CCNF cyclin F -4.49841
FEN1 flap structure-specific endonuclease 1 -4.48559
HJURP Holliday junction recognition protein -4.48006
MCM5 minichromosome maintenance complex component 5 -4.44878
HMG20B high mobility group 20B -4.44276
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.41208
GINS2 GINS complex subunit 2 (Psf2 homolog) -4.39954
PARP1 poly (ADP-ribose) polymerase 1 -4.39238
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -4.36422
SH3D19 SH3 domain containing 19 -4.33692
ALDOC aldolase C, fructose-bisphosphate -4.33653
MSH2 mutS homolog 2 -4.29414
PBK PDZ binding kinase -4.28527
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -4.27913
CENPQ centromere protein Q -4.22284
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.21901
SMC4 structural maintenance of chromosomes 4 -4.21289
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -4.18133
NDC80 NDC80 kinetochore complex component -4.14748
TROAP trophinin associated protein -4.07006
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -4.05575
ETFB electron-transfer-flavoprotein, beta polypeptide -4.04042
MKI67 marker of proliferation Ki-67 -4.03722
CDC6 cell division cycle 6 -4.02921
EXO1 exonuclease 1 -4.01114
INSIG1 insulin induced gene 1 -4.00059
CDCA4 cell division cycle associated 4 -3.97822
SPDL1 spindle apparatus coiled-coil protein 1 -3.97062
NCAPG2 non-SMC condensin II complex, subunit G2 -3.96394
GTSE1 G-2 and S-phase expressed 1 -3.94427
DHFR dihydrofolate reductase -3.93238
OIP5 Opa interacting protein 5 -3.91526
LDHD lactate dehydrogenase D -3.91205
CENPN centromere protein N -3.9006
RRM2 ribonucleotide reductase M2 -3.88972
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.88855
DONSON downstream neighbor of SON -3.88452
NEIL3 nei endonuclease VIII-like 3 (E. coli) -3.88193
PARPBP PARP1 binding protein -3.86437
RACGAP1 Rac GTPase activating protein 1 -3.8603
TK1 thymidine kinase 1, soluble -3.85035
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.80974
KIF22 kinesin family member 22 -3.74129
HOXA5 homeobox A5 -3.72913
MIS18A MIS18 kinetochore protein A -3.69585
ARHGAP11A Rho GTPase activating protein 11A -3.68782
TTK TTK protein kinase -3.64032
RFC3 replication factor C (activator 1) 3, 38kDa -3.63559
EXOSC9 exosome component 9 -3.6248
TACC3 transforming, acidic coiled-coil containing protein 3 -3.61988
NEK2 NIMA-related kinase 2 -3.60788
FAM200C family with sequence similarity 200 member C -3.60441
DBF4 DBF4 zinc finger -3.60231
GEMIN2 gem (nuclear organelle) associated protein 2 -3.5907
FIRRM FIGNL1 interacting regulator of recombination and mitosis -3.57413
SNRPA small nuclear ribonucleoprotein polypeptide A -3.56535
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.53021
CENPI centromere protein I -3.5297
CDC25C cell division cycle 25C -3.52908
NUP93 nucleoporin 93kDa -3.52495
RRM1 ribonucleotide reductase M1 -3.50506
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -3.50354
HADH hydroxyacyl-CoA dehydrogenase -3.49229
FOXM1 forkhead box M1 -3.48634
DSN1 DSN1, MIS12 kinetochore complex component -3.48152
ERCC6L excision repair cross-complementation group 6-like -3.48103
PTTG1 pituitary tumor-transforming 1 -3.47524
CEP55 centrosomal protein 55kDa -3.46962
APOO apolipoprotein O -3.45205
KIF18A kinesin family member 18A -3.43009
MANF mesencephalic astrocyte-derived neurotrophic factor -3.4229
CDK4 cyclin-dependent kinase 4 -3.37818
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -3.36838
KIF23 kinesin family member 23 -3.35783
DTYMK deoxythymidylate kinase (thymidylate kinase) -3.33131
VRK1 vaccinia related kinase 1 -3.33097
RBL1 retinoblastoma-like 1 -3.32812
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -3.32587
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.32291
SHCBP1 SHC SH2-domain binding protein 1 -3.31872
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -3.31275
KIFC1 kinesin family member C1 -3.30269
RPIA ribose 5-phosphate isomerase A -3.29513
MCM7 minichromosome maintenance complex component 7 -3.2917
CETN3 centrin, EF-hand protein, 3 -3.28833
CDT1 chromatin licensing and DNA replication factor 1 -3.28307
HMGB2 high mobility group box 2 -3.27013
HDAC2 histone deacetylase 2 -3.26092
MCM10 minichromosome maintenance complex component 10 -3.2599
CDC7 cell division cycle 7 -3.23597
RPP30 ribonuclease P/MRP 30kDa subunit -3.22628
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.22436
FANCI Fanconi anemia, complementation group I -3.22303
CLIC2 chloride intracellular channel 2 -3.21483
USP39 ubiquitin specific peptidase 39 -3.21209
E2F8 E2F transcription factor 8 -3.17892
SKA1 spindle and kinetochore associated complex subunit 1 -3.17067
NUBP2 nucleotide binding protein 2 -3.16703
MOCS2 molybdenum cofactor synthesis 2 -3.16636
ELP4 elongator acetyltransferase complex subunit 4 -3.16215
CHAF1A chromatin assembly factor 1, subunit A (p150) -3.16208
HSPD1 heat shock 60kDa protein 1 (chaperonin) -3.16195
BPHL biphenyl hydrolase-like (serine hydrolase) -3.16121
DEK DEK proto-oncogene -3.1564
WDHD1 WD repeat and HMG-box DNA binding protein 1 -3.1445
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -3.14296
CENPF centromere protein F, 350/400kDa -3.12734
ATG5 autophagy related 5 -3.12363
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -3.12347
TRMT5 tRNA methyltransferase 5 -3.12318
POGLUT2 protein O-glucosyltransferase 2 -3.11036
RFC4 replication factor C (activator 1) 4, 37kDa -3.10767
CHAF1B chromatin assembly factor 1, subunit B (p60) -3.10643
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 -3.10271
DSCC1 DNA replication and sister chromatid cohesion 1 -3.08638
GINS3 GINS complex subunit 3 (Psf3 homolog) -3.08189
CDCA8 cell division cycle associated 8 -3.08054
TMPO thymopoietin -3.07638
MCM6 minichromosome maintenance complex component 6 -3.0722
SRSF2 serine/arginine-rich splicing factor 2 -3.06798
CBX3 chromobox homolog 3 -3.0508
CENPS-CORT CENPS-CORT readthrough -3.04471
TOMM34 translocase of outer mitochondrial membrane 34 -3.04053
RAB27A RAB27A, member RAS oncogene family -3.03314
BORA bora, aurora kinase A activator -3.0302
RMI1 RecQ mediated genome instability 1 -3.02898
GEMIN6 gem (nuclear organelle) associated protein 6 -3.02785
NUP37 nucleoporin 37kDa -3.00619
ADD3 adducin 3 (gamma) -3.00586
HMGN1 high mobility group nucleosome binding domain 1 -2.99624
MAT2B methionine adenosyltransferase II, beta -2.9931
ZNF267 zinc finger protein 267 -2.98479
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.98158
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.98009
CASP8AP2 caspase 8 associated protein 2 -2.97895
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.97291
MCM4 minichromosome maintenance complex component 4 -2.96955
SPAG5 sperm associated antigen 5 -2.95257
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.94962
MEX3D mex-3 RNA binding family member D -2.93956
UBE2S ubiquitin-conjugating enzyme E2S -2.93385
PRC1 protein regulator of cytokinesis 1 -2.92768
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.9118
ZNF83 zinc finger protein 83 -2.91003
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.89214
ERGIC2 ERGIC and golgi 2 -2.88747
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.88651
VBP1 von Hippel-Lindau binding protein 1 -2.88436
USP1 ubiquitin specific peptidase 1 -2.88297
NUP54 nucleoporin 54kDa -2.86826
ILF2 interleukin enhancer binding factor 2 -2.86366
MSH6 mutS homolog 6 -2.85655
NUP62 nucleoporin 62kDa -2.84884
TCERG1 transcription elongation regulator 1 -2.84283
SOBP sine oculis binding protein homolog (Drosophila) -2.83754
TSPAN3 tetraspanin 3 -2.82943
CENPE centromere protein E, 312kDa -2.82714
ZDHHC6 zinc finger, DHHC-type containing 6 -2.82679
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.82152
MSMO1 methylsterol monooxygenase 1 -2.81106
DNM1L dynamin 1-like -2.80829
MMP9 matrix metallopeptidase 9 -2.80279
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.79851
FBL fibrillarin -2.79117
KLHDC3 kelch domain containing 3 -2.79072
BCAP29 B-cell receptor-associated protein 29 -2.78047
ANAPC10 anaphase promoting complex subunit 10 -2.77766
AIDA axin interactor, dorsalization associated -2.77339
CDC23 cell division cycle 23 -2.76052
SAP30 Sin3A-associated protein, 30kDa -2.759
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.75064
UGP2 UDP-glucose pyrophosphorylase 2 -2.74173
NCAPG non-SMC condensin I complex, subunit G -2.74132
CTSO cathepsin O -2.72655
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.72185
ELOVL6 ELOVL fatty acid elongase 6 -2.72044
YEATS4 YEATS domain containing 4 -2.72036
SCML1 sex comb on midleg-like 1 (Drosophila) -2.7148
CENPM centromere protein M -2.71221
TEX30 testis expressed 30 -2.70655
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -2.69701
CD320 CD320 molecule -2.68875
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.68661
TPK1 thiamin pyrophosphokinase 1 -2.68658
TDO2 tryptophan 2,3-dioxygenase -2.68615
TMEM50B transmembrane protein 50B -2.6838
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.68223
CKS1B CDC28 protein kinase regulatory subunit 1B -2.67401
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.6692
ATAD5 ATPase family, AAA domain containing 5 -2.65667
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -2.65126
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.65046
ABHD3 abhydrolase domain containing 3 -2.65022
CYCS cytochrome c, somatic -2.64853
BRCA1 breast cancer 1, early onset -2.64408
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -2.64383
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.63948
MDH1 malate dehydrogenase 1, NAD (soluble) -2.6351
GPHN gephyrin -2.62729
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -2.62328
H2AX H2A.X variant histone -2.62258
TUBG1 tubulin, gamma 1 -2.61885
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.61555
RBMX RNA binding motif protein, X-linked -2.61296
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.61017
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough -2.60603
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.60434
CCNK cyclin K -2.59523
IPO7 importin 7 -2.57633
NEMP1 nuclear envelope integral membrane protein 1 -2.56798
GOLT1B golgi transport 1B -2.56722
PCLAF PCNA clamp associated factor -2.56685
HELLS helicase, lymphoid-specific -2.56428
RANBP1 RAN binding protein 1 -2.55013
KIAA0586 KIAA0586 -2.5488
NCAPD3 non-SMC condensin II complex, subunit D3 -2.54659
SELENOT selenoprotein T -2.54631
MXD3 MAX dimerization protein 3 -2.53956
PRKD3 protein kinase D3 -2.52777
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -2.52242
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.51558
COMMD10 COMM domain containing 10 -2.51557
GPN3 GPN-loop GTPase 3 -2.5011
ZMYM1 zinc finger, MYM-type 1 -2.49461
ZWINT ZW10 interacting kinetochore protein -2.49306
HMGB1 high mobility group box 1 -2.48134
JMJD6 jumonji domain containing 6 -2.47546
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.47328
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -2.47159
BLM Bloom syndrome, RecQ helicase-like -2.4708
TUBGCP4 tubulin, gamma complex associated protein 4 -2.46385
MTERF3 mitochondrial transcription termination factor 3 -2.46262
BRIX1 BRX1, biogenesis of ribosomes -2.45936
CDK2 cyclin-dependent kinase 2 -2.45927
TRAIP TRAF interacting protein -2.4549
CNOT8 CCR4-NOT transcription complex, subunit 8 -2.45251
LSAMP limbic system-associated membrane protein -2.45163
PLK4 polo-like kinase 4 -2.44765
CLCC1 chloride channel CLIC-like 1 -2.44522
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.44082
TIPIN TIMELESS interacting protein -2.43826
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.43736
H1-3 H1.3 linker histone, cluster member -2.43505
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -2.43443
NUP88 nucleoporin 88kDa -2.43192
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -2.43162
COQ3 coenzyme Q3 methyltransferase -2.42838
FKBP5 FK506 binding protein 5 -2.41402
HOXA2 homeobox A2 -2.40904
HOXD10 homeobox D10 -2.40528
GMCL1 germ cell-less, spermatogenesis associated 1 -2.4047
HMGN2 high mobility group nucleosomal binding domain 2 -2.40335
CCNE2 cyclin E2 -2.39908
NUP43 nucleoporin 43kDa -2.39814
FBN1 fibrillin 1 -2.39167
ADGRB3 adhesion G protein-coupled receptor B3 -2.39141
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -2.38972
TBC1D15 TBC1 domain family, member 15 -2.37776
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.37695
CKAP2 cytoskeleton associated protein 2 -2.37629
GLRX5 glutaredoxin 5 -2.37572
MPHOSPH9 M-phase phosphoprotein 9 -2.37066
RBBP7 retinoblastoma binding protein 7 -2.36695
PMP2 peripheral myelin protein 2 -2.36515
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.36397
ZNF253 zinc finger protein 253 -2.35688
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.35372
ASF1A anti-silencing function 1A histone chaperone -2.35208
DCTPP1 dCTP pyrophosphatase 1 -2.34661
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -2.34407
MIS18BP1 MIS18 binding protein 1 -2.34169
MMD monocyte to macrophage differentiation-associated -2.3368
LMNB1 lamin B1 -2.33571
ARC activity-regulated cytoskeleton-associated protein -2.33569
E2F1 E2F transcription factor 1 -2.3355
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.33494
TUBB6 tubulin, beta 6 class V -2.33372
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.33002
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.32942
AUH AU RNA binding protein/enoyl-CoA hydratase -2.32742
TTC33 tetratricopeptide repeat domain 33 -2.3267
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.32338
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.32197
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase -2.31942
MRPL4 mitochondrial ribosomal protein L4 -2.31639
AMDHD2 amidohydrolase domain containing 2 -2.31508
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.31197
TRAPPC13 trafficking protein particle complex 13 -2.31108
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.30806
POLK polymerase (DNA directed) kappa -2.30595
GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 -2.30077
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.29862
RAD51AP1 RAD51 associated protein 1 -2.29839
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.29621
SMC3 structural maintenance of chromosomes 3 -2.29589
PFAS phosphoribosylformylglycinamidine synthase -2.28975
NID2 nidogen 2 (osteonidogen) -2.28802
H2AZ1 H2A.Z variant histone 1 -2.28787
MATR3 matrin 3 -2.2842
SIVA1 SIVA1, apoptosis-inducing factor -2.28389
NUP155 nucleoporin 155kDa -2.28349
CCNH cyclin H -2.28044
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -2.2802
PRRX1 paired related homeobox 1 -2.27997
GTF2A2 general transcription factor IIA, 2, 12kDa -2.26932
LOC102724594 splicing factor U2AF 35 kDa subunit -2.26809
ECT2 epithelial cell transforming 2 -2.25962
ETV1 ets variant 1 -2.25712
PGRMC1 progesterone receptor membrane component 1 -2.25154
PTBP1 polypyrimidine tract binding protein 1 -2.2514
RFWD3 ring finger and WD repeat domain 3 -2.25047
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.24958
MRPL12 mitochondrial ribosomal protein L12 -2.24769
DPY19L4 dpy-19-like 4 (C. elegans) -2.24711
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -2.24547
NSD2 nuclear receptor binding SET domain protein 2 -2.24377
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.24294
PRMT3 protein arginine methyltransferase 3 -2.24136
LAMB1 laminin, beta 1 -2.23924
C1QL1 complement component 1, q subcomponent-like 1 -2.23784
CENPU centromere protein U -2.23547
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -2.2336
H2AZ2 H2A.Z variant histone 2 -2.23242
SLAMF8 SLAM family member 8 -2.22998
LDHB lactate dehydrogenase B -2.22862
SMAD9 SMAD family member 9 -2.22048
LIFR leukemia inhibitory factor receptor alpha -2.21992
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -2.21867
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.21547
METTL4 methyltransferase like 4 -2.21031
ISOC1 isochorismatase domain containing 1 -2.20999
RAD54B RAD54 homolog B (S. cerevisiae) -2.20413
MRPL39 mitochondrial ribosomal protein L39 -2.20404
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.20219
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.20142
ELAVL1 ELAV like RNA binding protein 1 -2.19946
IL13RA1 interleukin 13 receptor, alpha 1 -2.19359
KIF2A kinesin heavy chain member 2A -2.19262
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.18934
MIS12 MIS12 kinetochore complex component -2.18928
WDR76 WD repeat domain 76 -2.18674
HOXD11 homeobox D11 -2.18392
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -2.18279
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.18274
TUBD1 tubulin, delta 1 -2.18253
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.17864
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -2.17619
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 -2.17184
EIF4E eukaryotic translation initiation factor 4E -2.17045
ZNF207 zinc finger protein 207 -2.16486
ZNF587B zinc finger protein 587B -2.16458
YAF2 YY1 associated factor 2 -2.1601
GMPPB GDP-mannose pyrophosphorylase B -2.15949
RSBN1 round spermatid basic protein 1 -2.15891
RNF130 ring finger protein 130 -2.15782
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -2.15569
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.15432
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.14724
FANCA Fanconi anemia, complementation group A -2.14628
DPYD dihydropyrimidine dehydrogenase -2.1444
MRPS27 mitochondrial ribosomal protein S27 -2.14154
SLCO2B1 solute carrier organic anion transporter family, member 2B1 -2.14078
COL6A2 collagen, type VI, alpha 2 -2.14061
MRPS7 mitochondrial ribosomal protein S7 -2.1375
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.13349
RBM14-RBM4 RBM14-RBM4 readthrough -2.13293
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -2.13271
CNTLN centlein, centrosomal protein -2.13239
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.12582
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -2.12567
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -2.1246
PLAT plasminogen activator, tissue -2.12407
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.12406
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -2.12022
PCBP1 poly(rC) binding protein 1 -2.11505
APEH acylaminoacyl-peptide hydrolase -2.11369
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 -2.1136
PDLIM3 PDZ and LIM domain 3 -2.1127
PDIA3 protein disulfide isomerase family A, member 3 -2.11199
H1-10 H1.10 linker histone -2.10883
IFI16 interferon, gamma-inducible protein 16 -2.10749
AP2M1 adaptor-related protein complex 2, mu 1 subunit -2.10506
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.10487
MRPL17 mitochondrial ribosomal protein L17 -2.10002
SRSF10 serine/arginine-rich splicing factor 10 -2.09997
CEP192 centrosomal protein 192kDa -2.09907
MEIS2 Meis homeobox 2 -2.09838
LARP7 La ribonucleoprotein domain family, member 7 -2.09795
MAPK9 mitogen-activated protein kinase 9 -2.09642
QARS1 glutaminyl-tRNA synthetase 1 -2.09607
THOP1 thimet oligopeptidase 1 -2.09342
TXLNG taxilin gamma -2.09158
CMC2 C-x(9)-C motif containing 2 -2.09141
CKS2 CDC28 protein kinase regulatory subunit 2 -2.08296
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -2.08108
RBP1 retinol binding protein 1, cellular -2.08063
PPP6R1 protein phosphatase 6, regulatory subunit 1 -2.07941
TMX1 thioredoxin-related transmembrane protein 1 -2.07699
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -2.07567
PRIM1 primase, DNA, polypeptide 1 (49kDa) -2.07469
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.07128
GLO1 glyoxalase I -2.06957
HAUS3 HAUS augmin-like complex, subunit 3 -2.06683
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -2.06246
PRPF31 pre-mRNA processing factor 31 -2.0621
GPR20 G protein-coupled receptor 20 -2.06202
SMN2 survival of motor neuron 2, centromeric -2.06171
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit -2.06122
PDIA6 protein disulfide isomerase family A, member 6 -2.05995
TMEM38B transmembrane protein 38B -2.05975
MAP7D3 MAP7 domain containing 3 -2.0569
NEK4 NIMA-related kinase 4 -2.055
PRMT1 protein arginine methyltransferase 1 -2.055
FZD4 frizzled class receptor 4 -2.05433
ANKRD10 ankyrin repeat domain 10 -2.0528
GDF10 growth differentiation factor 10 -2.04676
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -2.03952
CADPS2 Ca++-dependent secretion activator 2 -2.03885
PDE8B phosphodiesterase 8B -2.03786
FANCG Fanconi anemia, complementation group G -2.03686
GALP galanin-like peptide -2.03551
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.02889
GIN1 gypsy retrotransposon integrase 1 -2.02621
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.02506
CS citrate synthase -2.02093
MMP13 matrix metallopeptidase 13 -2.02022
BLMH bleomycin hydrolase -2.01959
TMED5 transmembrane emp24 protein transport domain containing 5 -2.01835
OSGEP O-sialoglycoprotein endopeptidase -2.01808
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.01749
TMEM109 transmembrane protein 109 -2.01562
GET3 guided entry of tail-anchored proteins factor 3, ATPase -2.01381
TNIK TRAF2 and NCK interacting kinase -2.01152
ZFP37 ZFP37 zinc finger protein -2.0106
SPARCL1 SPARC-like 1 (hevin) -2.00738
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -2.0068
LTF lactotransferrin -2.00621
EML4 echinoderm microtubule associated protein like 4 -2.00556
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -2.00545
TP53RK TP53 regulating kinase -2.00465
DUT deoxyuridine triphosphatase -2.0005
CDK14 cyclin-dependent kinase 14 -2.00035