CRCGN016_MCF10A.WT.HP_24H:B03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:B03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 3.63598
ADRB2 adrenoceptor beta 2, surface 3.52625
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.39214
SPAG4 sperm associated antigen 4 3.34573
COMP cartilage oligomeric matrix protein 2.73656
KLHL9 kelch-like family member 9 2.40159
CDC45 cell division cycle 45 2.35971
EML3 echinoderm microtubule associated protein like 3 2.3439
ATAD3A ATPase family, AAA domain containing 3A 2.08577

decreased expression

Symbol Name Standardized Value
CD44 CD44 molecule (Indian blood group) -3.84408
PCNA proliferating cell nuclear antigen -3.78155
GLRX glutaredoxin (thioltransferase) -3.47568
HSPA8 heat shock 70kDa protein 8 -3.32511
CCNB2 cyclin B2 -3.06574
NT5DC2 5'-nucleotidase domain containing 2 -2.76683
SLC25A46 solute carrier family 25, member 46 -2.12699
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.10797
LRRC8E leucine rich repeat containing 8 family, member E -2.09711
OXA1L oxidase (cytochrome c) assembly 1-like -2.08622
RPS5 ribosomal protein S5 -2.08052
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -2.07568
LMBRD1 LMBR1 domain containing 1 -2.07394
KIF5C kinesin family member 5C -2.04683
PYGL phosphorylase, glycogen, liver -2.02267
DYNLT3 dynein, light chain, Tctex-type 3 -2.02137
RSU1 Ras suppressor protein 1 -2.01518