CRCGN016_MCF10A.WT.HP_24H:B04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:B04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PNKP polynucleotide kinase 3'-phosphatase 4.1784
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.10757
ZW10 zw10 kinetochore protein 2.97973
TESK1 testis-specific kinase 1 2.83733
PPARG peroxisome proliferator-activated receptor gamma 2.82893
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.4384
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.2956
PTK2 protein tyrosine kinase 2 2.17643
ACAA1 acetyl-CoA acyltransferase 1 2.1031
TIAM1 T-cell lymphoma invasion and metastasis 1 2.03303
RBM15B RNA binding motif protein 15B 2.02927

decreased expression

Symbol Name Standardized Value
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.83133
CHIC2 cysteine-rich hydrophobic domain 2 -3.68797
PARP2 poly (ADP-ribose) polymerase 2 -3.60116
KIF20A kinesin family member 20A -3.5419
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.29647
SCYL3 SCY1-like 3 (S. cerevisiae) -3.26893
BASP1 brain abundant, membrane attached signal protein 1 -3.21843
GDF15 growth differentiation factor 15 -3.1085
RPIA ribose 5-phosphate isomerase A -3.05953
TLCD3A TLC domain containing 3A -2.2538
TUBA4A tubulin, alpha 4a -2.17657
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -2.12813