CRCGN016_MCF10A.WT.HP_24H:B06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:B06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 3.62929
KLHL21 kelch-like family member 21 3.48416
EAPP E2F-associated phosphoprotein 2.95785
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.81235
TCEA2 transcription elongation factor A (SII), 2 2.72125
IGFBP3 insulin-like growth factor binding protein 3 2.58635
TPD52L2 tumor protein D52-like 2 2.10836

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -4.43137
BASP1 brain abundant, membrane attached signal protein 1 -3.72978
ARID4B AT rich interactive domain 4B (RBP1-like) -3.7222
MRPL58 mitochondrial ribosomal protein L58 -3.4506
NUP85 nucleoporin 85kDa -3.41383
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.33767
SGK1 serum/glucocorticoid regulated kinase 1 -2.92998
TIMP1 TIMP metallopeptidase inhibitor 1 -2.90622
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.86643
MRPS7 mitochondrial ribosomal protein S7 -2.73147
ATP5PD ATP synthase peripheral stalk subunit d -2.70223
MAPK13 mitogen-activated protein kinase 13 -2.60718
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.52061
JMJD6 jumonji domain containing 6 -2.5197
CDR2L cerebellar degeneration-related protein 2-like -2.46527
KCTD2 potassium channel tetramerization domain containing 2 -2.44534
HEATR1 HEAT repeat containing 1 -2.36038
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.32678
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.3173