CRCGN016_MCF10A.WT.HP_24H:B08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3',4,4'-tetrachloro-1,1'-biphenyl 31.81 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:B08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.46791
SQOR sulfide quinone oxidoreductase 4.41936
AGR2 anterior gradient 2 3.07805
GATA3 GATA binding protein 3 3.05453
ZMIZ1 zinc finger, MIZ-type containing 1 2.9199
PPARG peroxisome proliferator-activated receptor gamma 2.77527
INTS3 integrator complex subunit 3 2.70853
TPD52L2 tumor protein D52-like 2 2.6209
ACAA1 acetyl-CoA acyltransferase 1 2.28198
SMIM40 small integral membrane protein 40 2.27647
BACE2 beta-site APP-cleaving enzyme 2 2.17627
ANO10 anoctamin 10 2.16475
STAP2 signal transducing adaptor family member 2 2.15045
GADD45A growth arrest and DNA-damage-inducible, alpha 2.12407
TBX2 T-box 2 2.12362
CHI3L2 chitinase 3-like 2 2.03797
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 2.02095

decreased expression

Symbol Name Standardized Value
PRPF4 pre-mRNA processing factor 4 -4.69958
SLC35F2 solute carrier family 35, member F2 -4.49855
BASP1 brain abundant, membrane attached signal protein 1 -4.0714
LSR lipolysis stimulated lipoprotein receptor -2.82318
PCCB propionyl CoA carboxylase, beta polypeptide -2.7878
IPO13 importin 13 -2.78739
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.69661
NVL nuclear VCP-like -2.59256
HMG20B high mobility group 20B -2.53141
CCNB1 cyclin B1 -2.42848
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.26897
SLC31A1 solute carrier family 31 (copper transporter), member 1 -2.08455
BSPRY B-box and SPRY domain containing -2.03833
CDC37L1 cell division cycle 37-like 1 -2.02222