CRCGN016_MCF10A.WT.HP_24H:B09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3',4,4'-tetrachloro-1,1'-biphenyl 10.6 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:B09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 4.37675
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.19542
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 3.18539
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.45922
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.38385
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 2.32037
MELK maternal embryonic leucine zipper kinase 2.22135
HMGXB3 HMG box domain containing 3 2.15572
LUC7L LUC7-like (S. cerevisiae) 2.01634
COMP cartilage oligomeric matrix protein 2.00557

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -5.34107
YME1L1 YME1-like 1 ATPase -5.02801
NT5DC2 5'-nucleotidase domain containing 2 -4.70768
TEX10 testis expressed 10 -4.24116
PCCB propionyl CoA carboxylase, beta polypeptide -4.18912
ABI1 abl-interactor 1 -3.63438
KRT14 keratin 14, type I -3.16974
SORBS3 sorbin and SH3 domain containing 3 -3.16621
BPHL biphenyl hydrolase-like (serine hydrolase) -3.06572
RBM34 RNA binding motif protein 34 -2.80817
GDI2 GDP dissociation inhibitor 2 -2.75934
ATP5F1C ATP synthase F1 subunit gamma -2.59038
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.5776
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.57103
ACAA1 acetyl-CoA acyltransferase 1 -2.45055
MTPAP mitochondrial poly(A) polymerase -2.43775
MT1X metallothionein 1X -2.24608
OPTN optineurin -2.19053
ARID4B AT rich interactive domain 4B (RBP1-like) -2.16579
WAC WW domain containing adaptor with coiled-coil -2.12603
RPS5 ribosomal protein S5 -2.01508
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -2.00567
GTPBP4 GTP binding protein 4 -2.00487
KIN Kin17 DNA and RNA binding protein -2.00158
SFTPD surfactant protein D -2.00031