CRCGN016_MCF10A.WT.HP_24H:B11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description chrysene 31.07 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

28 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:B11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 5.21118
KLHL21 kelch-like family member 21 5.06225
NOTCH1 notch 1 5.02092
CXCR4 chemokine (C-X-C motif) receptor 4 4.34246
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 4.05852
NOL9 nucleolar protein 9 2.85062
TMEM109 transmembrane protein 109 2.65691
VGLL4 vestigial-like family member 4 2.47608
CCL2 chemokine (C-C motif) ligand 2 2.35614
FST follistatin 2.27061
EVL Enah/Vasp-like 2.26708
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.16888
KAT6B K(lysine) acetyltransferase 6B 2.15413
TCEA2 transcription elongation factor A (SII), 2 2.12825
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.06136
OLFML2B olfactomedin-like 2B 2.01154

decreased expression

Symbol Name Standardized Value
CYCS cytochrome c, somatic -4.8148
THAP11 THAP domain containing 11 -3.24152
ARID4B AT rich interactive domain 4B (RBP1-like) -2.99671
CANT1 calcium activated nucleotidase 1 -2.70367
DUSP14 dual specificity phosphatase 14 -2.56
ACAA1 acetyl-CoA acyltransferase 1 -2.52491
MSMO1 methylsterol monooxygenase 1 -2.51644
NCAM2 neural cell adhesion molecule 2 -2.34246
ARL5A ADP-ribosylation factor-like 5A -2.27367
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -2.17906
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.11178
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.03382