| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | TCDD-dioxin 0.03 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:B14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AGR2 | anterior gradient 2 | 6.43052 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 5.24818 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 4.99123 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 4.75796 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.39845 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 3.05469 |
| IL1B | interleukin 1, beta | 2.94631 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.79294 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.78609 |
| NEFH | neurofilament, heavy polypeptide | 2.59975 |
| CAVIN2 | caveolae associated protein 2 | 2.58938 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 2.58232 |
| EREG | epiregulin | 2.34262 |
| CAB39 | calcium binding protein 39 | 2.34181 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.28832 |
| ASTN2 | astrotactin 2 | 2.24312 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 2.21122 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 2.18724 |
| EXOC2 | exocyst complex component 2 | 2.15486 |
| TMEM164 | transmembrane protein 164 | 2.13453 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 2.12343 |
| CDC25B | cell division cycle 25B | 2.11175 |
| UTRN | utrophin | 2.11025 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.08303 |
| TPM1 | tropomyosin 1 (alpha) | 2.06914 |
| ZBED2 | zinc finger, BED-type containing 2 | 2.03172 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.01904 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 2.01179 |
| IQSEC3 | IQ motif and Sec7 domain 3 | 2.00823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCCB | propionyl CoA carboxylase, beta polypeptide | -8.35664 |
| KIF14 | kinesin family member 14 | -4.96927 |
| ATF5 | activating transcription factor 5 | -4.78034 |
| GNAS | GNAS complex locus | -4.26489 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -4.16949 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -3.9135 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -3.74149 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -3.36493 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -3.31319 |
| GDF15 | growth differentiation factor 15 | -3.30229 |
| JMJD6 | jumonji domain containing 6 | -3.22313 |
| LAP3 | leucine aminopeptidase 3 | -3.06002 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.94149 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | -2.83761 |
| ZNF281 | zinc finger protein 281 | -2.52107 |
| STXBP2 | syntaxin binding protein 2 | -2.3395 |
| RBM42 | RNA binding motif protein 42 | -2.26694 |
| AKR1D1 | aldo-keto reductase family 1, member D1 | -2.20844 |
| CLDN6 | claudin 6 | -2.18307 |
| NELFCD | negative elongation factor complex member C/D | -2.1587 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | -2.14961 |
| CD70 | CD70 molecule | -2.14583 |
| ATG9A | autophagy related 9A | -2.1175 |
| USP2 | ubiquitin specific peptidase 2 | -2.09414 |
| DUSP14 | dual specificity phosphatase 14 | -2.09159 |
| SFXN3 | sideroflexin 3 | -2.05683 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -2.05674 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | -2.0526 |
| COQ9 | coenzyme Q9 | -2.05159 |
| KLRC4-KLRK1 | KLRC4-KLRK1 readthrough | -2.05007 |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | -2.04833 |
| HGFAC | HGF activator | -2.04637 |
| TBCB | tubulin folding cofactor B | -2.01182 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -2.01108 |
