CRCGN016_MCF10A.WT.HP_24H:B16 Gene Set
Genes
41 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:B16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DNAJB1
|
DnaJ (Hsp40) homolog, subfamily B, member 1
|
4.41082
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
2.93666
|
|
UBE2L6
|
ubiquitin-conjugating enzyme E2L 6
|
2.84065
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
2.66649
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.5697
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
2.39199
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
2.34278
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.31244
|
|
IL1B
|
interleukin 1, beta
|
2.31032
|
|
MAT2A
|
methionine adenosyltransferase II, alpha
|
2.22374
|
|
SPAG4
|
sperm associated antigen 4
|
2.21329
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.20914
|
|
CDC25B
|
cell division cycle 25B
|
2.08815
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-5.63078
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.07187
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-5.06816
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.03295
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.3719
|
|
CBR3
|
carbonyl reductase 3
|
-3.21986
|
|
UFM1
|
ubiquitin-fold modifier 1
|
-3.14745
|
|
ITPA
|
inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
|
-3.03477
|
|
TMEM230
|
transmembrane protein 230
|
-2.81578
|
|
SNRPB2
|
small nuclear ribonucleoprotein polypeptide B
|
-2.54773
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
-2.49452
|
|
KRT14
|
keratin 14, type I
|
-2.45513
|
|
SNRPB
|
small nuclear ribonucleoprotein polypeptides B and B1
|
-2.31749
|
|
LYRM1
|
LYR motif containing 1
|
-2.29666
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.2895
|
|
CSRP1
|
cysteine and glycine-rich protein 1
|
-2.24956
|
|
CRTAM
|
cytotoxic and regulatory T cell molecule
|
-2.23925
|
|
NSFL1C
|
NSFL1 (p97) cofactor (p47)
|
-2.21182
|
|
CDS2
|
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
|
-2.19436
|
|
AP5S1
|
adaptor-related protein complex 5, sigma 1 subunit
|
-2.16343
|
|
PLK1
|
polo-like kinase 1
|
-2.1525
|
|
SAA4
|
serum amyloid A4, constitutive
|
-2.13791
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-2.09637
|
|
CBR1
|
carbonyl reductase 1
|
-2.08071
|
|
NXT1
|
nuclear transport factor 2-like export factor 1
|
-2.0746
|
|
DDRGK1
|
DDRGK domain containing 1
|
-2.06914
|
|
APMAP
|
adipocyte plasma membrane associated protein
|
-2.0539
|
|
ZNF281
|
zinc finger protein 281
|
-2.04874
|
