CRCGN016_MCF10A.WT.HP_24H:B18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ficz 0.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

75 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:B18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CRELD2 cysteine-rich with EGF-like domains 2 4.65219
SNAP25 synaptosomal-associated protein, 25kDa 4.1438
ARID5B AT rich interactive domain 5B (MRF1-like) 4.08686
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.81302
E2F2 E2F transcription factor 2 3.64119
STK10 serine/threonine kinase 10 3.41163
GATA3 GATA binding protein 3 3.25623
ABHD4 abhydrolase domain containing 4 3.24402
MTA2 metastasis associated 1 family, member 2 2.99624
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.82484
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.7392
STMN2 stathmin 2 2.57652
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.50159
AGR2 anterior gradient 2 2.47995
RPH3A rabphilin 3A 2.45969
PRDM16 PR domain containing 16 2.44493
INCENP inner centromere protein antigens 135/155kDa 2.43982
NLRP1 NLR family, pyrin domain containing 1 2.42453
MRLN myoregulin 2.38989
CCNL1 cyclin L1 2.32795
TP73 tumor protein p73 2.28775
MFAP5 microfibrillar associated protein 5 2.266
IL1B interleukin 1, beta 2.20439
GALR3 galanin receptor 3 2.17911
KLF15 Kruppel-like factor 15 2.16188
HEG1 heart development protein with EGF-like domains 1 2.14378
ANGPT4 angiopoietin 4 2.13122
TAGLN3 transgelin 3 2.11768
MCHR1 melanin-concentrating hormone receptor 1 2.10919
IL12RB1 interleukin 12 receptor, beta 1 2.1082
OVOL1 ovo-like zinc finger 1 2.10372
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 2.0934
DKKL1 dickkopf-like 1 2.08976
PCDHGA9 protocadherin gamma subfamily A, 9 2.08248
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 2.07323
PAX1 paired box 1 2.06909
INSL6 insulin-like 6 2.06736
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 2.05918
GJB5 gap junction protein, beta 5, 31.1kDa 2.059
INSRR insulin receptor-related receptor 2.03544
HCRT hypocretin (orexin) neuropeptide precursor 2.03435
RLBP1 retinaldehyde binding protein 1 2.03379
KRTAP5-3 keratin associated protein 5-3 2.02672
CNGA3 cyclic nucleotide gated channel alpha 3 2.02507
TMEM40 transmembrane protein 40 2.02203
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 2.01856
RUNDC3A RUN domain containing 3A 2.01666
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.01522
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 2.00426

decreased expression

Symbol Name Standardized Value
YME1L1 YME1-like 1 ATPase -6.46638
HMG20B high mobility group 20B -6.17212
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.22872
HAT1 histone acetyltransferase 1 -3.72156
ABI1 abl-interactor 1 -3.52957
S100A8 S100 calcium binding protein A8 -3.39389
MTPAP mitochondrial poly(A) polymerase -3.22743
WAC WW domain containing adaptor with coiled-coil -2.96456
THAP11 THAP domain containing 11 -2.78356
KIF20A kinesin family member 20A -2.76313
RFC2 replication factor C (activator 1) 2, 40kDa -2.69175
BASP1 brain abundant, membrane attached signal protein 1 -2.67718
TOMM34 translocase of outer mitochondrial membrane 34 -2.63871
BPHL biphenyl hydrolase-like (serine hydrolase) -2.43417
CRTAP cartilage associated protein -2.4189
SCAND1 SCAN domain containing 1 -2.37253
PRPF18 pre-mRNA processing factor 18 -2.34416
PHYH phytanoyl-CoA 2-hydroxylase -2.16818
NGRN neugrin, neurite outgrowth associated -2.1628
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.12807
UFSP2 UFM1-specific peptidase 2 -2.12791
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.12514
TTI1 TELO2 interacting protein 1 -2.03638
KIF5B kinesin family member 5B -2.03287
SEPHS1 selenophosphate synthetase 1 -2.00503
OCEL1 occludin/ELL domain containing 1 -2.0012