CRCGN016_MCF10A.WT.HP_24H:B22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description chlorambucil 99.58 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

876 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:B22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 9.89281
LRP10 low density lipoprotein receptor-related protein 10 8.67001
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 8.55009
TICAM1 toll-like receptor adaptor molecule 1 7.39386
STAP2 signal transducing adaptor family member 2 7.02742
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 6.41689
DUSP14 dual specificity phosphatase 14 6.34032
MVP major vault protein 6.14549
RGS2 regulator of G-protein signaling 2 6.08761
WIF1 WNT inhibitory factor 1 6.03753
FHL2 four and a half LIM domains 2 5.73689
ABHD4 abhydrolase domain containing 4 5.64663
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 5.23736
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 4.95529
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 4.80559
NUCB2 nucleobindin 2 4.70252
DHRS2 dehydrogenase/reductase (SDR family) member 2 4.62307
PTPN1 protein tyrosine phosphatase, non-receptor type 1 4.532
INPP1 inositol polyphosphate-1-phosphatase 4.52022
PDLIM1 PDZ and LIM domain 1 4.47804
TMEM50A transmembrane protein 50A 4.39263
VAT1 vesicle amine transport 1 4.38939
GLRX glutaredoxin (thioltransferase) 4.30818
ADRB2 adrenoceptor beta 2, surface 4.28008
DDB2 damage-specific DNA binding protein 2, 48kDa 4.22458
TNIP1 TNFAIP3 interacting protein 1 4.20515
PLK3 polo-like kinase 3 4.19654
KRT34 keratin 34, type I 4.11593
DDA1 DET1 and DDB1 associated 1 4.09621
TP53I3 tumor protein p53 inducible protein 3 4.08855
MICALL1 MICAL-like 1 3.93028
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.89721
NOP10 NOP10 ribonucleoprotein 3.77698
GMIP GEM interacting protein 3.77648
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.77495
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.75712
NOTCH1 notch 1 3.75427
IRF9 interferon regulatory factor 9 3.75325
GRAMD2B GRAM domain containing 2B 3.73733
PTPN6 protein tyrosine phosphatase, non-receptor type 6 3.7304
STXBP1 syntaxin binding protein 1 3.72885
TUBB6 tubulin, beta 6 class V 3.68124
OPTN optineurin 3.66478
PHLDA3 pleckstrin homology-like domain, family A, member 3 3.62124
MINDY1 MINDY lysine 48 deubiquitinase 1 3.6085
ITPKC inositol-trisphosphate 3-kinase C 3.59337
CEMIP2 cell migration inducing hyaluronidase 2 3.58727
GPER1 G protein-coupled estrogen receptor 1 3.5461
TUFT1 tuftelin 1 3.52693
CAPN1 calpain 1, (mu/I) large subunit 3.51641
TMEM59 transmembrane protein 59 3.51041
MUC1 mucin 1, cell surface associated 3.49315
EPS8L2 EPS8-like 2 3.45694
SKIC2 SKI2 subunit of superkiller complex 3.45081
EPHA2 EPH receptor A2 3.44668
SYNGAP1 synaptic Ras GTPase activating protein 1 3.4338
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.40333
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.38798
SESN1 sestrin 1 3.38492
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 3.38191
MYH9 myosin, heavy chain 9, non-muscle 3.35153
CHIC2 cysteine-rich hydrophobic domain 2 3.34605
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 3.34103
FDXR ferredoxin reductase 3.33125
TP53BP2 tumor protein p53 binding protein 2 3.22608
FGFR4 fibroblast growth factor receptor 4 3.22083
MX1 MX dynamin-like GTPase 1 3.2126
CLTB clathrin, light chain B 3.16817
MKNK1 MAP kinase interacting serine/threonine kinase 1 3.15315
SQOR sulfide quinone oxidoreductase 3.15242
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 3.13673
SLC35B1 solute carrier family 35, member B1 3.11902
TIMP2 TIMP metallopeptidase inhibitor 2 3.09693
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 3.09458
KDM5A lysine (K)-specific demethylase 5A 3.09262
PLA2G15 phospholipase A2, group XV 3.0922
LPCAT3 lysophosphatidylcholine acyltransferase 3 3.08034
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 3.07586
NIT1 nitrilase 1 3.07267
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.06888
YIPF1 Yip1 domain family, member 1 3.05883
ALAS1 5'-aminolevulinate synthase 1 3.05437
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 3.04894
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.04846
TIGAR TP53 induced glycolysis regulatory phosphatase 3.03931
STAMBP STAM binding protein 3.03594
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 3.02961
STX4 syntaxin 4 3.02745
GRN granulin 3.01902
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.00949
GIPC1 GIPC PDZ domain containing family, member 1 2.99598
RAB4B RAB4B, member RAS oncogene family 2.98389
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.96791
IFI35 interferon-induced protein 35 2.95992
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.95835
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 2.93079
RPS27L ribosomal protein S27-like 2.92817
KCTD9 potassium channel tetramerization domain containing 9 2.92578
LOC102724428 serine/threonine-protein kinase SIK1 2.92086
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.9148
IL22RA1 interleukin 22 receptor, alpha 1 2.90929
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.90469
RETREG2 reticulophagy regulator family member 2 2.90445
TMEM40 transmembrane protein 40 2.90363
PGAP6 post-GPI attachment to proteins 6 2.89586
TOB1 transducer of ERBB2, 1 2.89128
KIF3C kinesin family member 3C 2.88977
ZDHHC24 zinc finger, DHHC-type containing 24 2.88098
ISG15 ISG15 ubiquitin-like modifier 2.8785
MAPK3 mitogen-activated protein kinase 3 2.87219
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.86702
HLA-G major histocompatibility complex, class I, G 2.8613
MAPK13 mitogen-activated protein kinase 13 2.84724
FERRY3 FERRY endosomal RAB5 effector complex subunit 3 2.84686
F11R F11 receptor 2.8456
ADGRE5 adhesion G protein-coupled receptor E5 2.84441
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 2.84369
ZMAT3 zinc finger, matrin-type 3 2.83977
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 2.83689
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.82123
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.81308
FOXO4 forkhead box O4 2.7949
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.79004
FURIN furin (paired basic amino acid cleaving enzyme) 2.78387
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.78169
HMOX1 heme oxygenase 1 2.77982
IGHMBP2 immunoglobulin mu binding protein 2 2.76771
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.75648
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.74547
SIRT2 sirtuin 2 2.73705
IFI27 interferon, alpha-inducible protein 27 2.73457
PERP PERP, TP53 apoptosis effector 2.73183
PGPEP1 pyroglutamyl-peptidase I 2.72525
RHOC ras homolog family member C 2.71819
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 2.71797
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.71433
SCRN1 secernin 1 2.71291
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.70916
CLDN4 claudin 4 2.70903
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.68939
IRF7 interferon regulatory factor 7 2.6861
LGALS9C lectin, galactoside-binding, soluble, 9C 2.68392
PLSCR1 phospholipid scramblase 1 2.67598
EHD1 EH-domain containing 1 2.66921
SPATA20 spermatogenesis associated 20 2.66164
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.65676
TRIM22 tripartite motif containing 22 2.65501
PMP22 peripheral myelin protein 22 2.64766
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.63817
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.63815
ACOX1 acyl-CoA oxidase 1, palmitoyl 2.63284
IL4R interleukin 4 receptor 2.62529
CHMP1B charged multivesicular body protein 1B 2.62434
CALCOCO2 calcium binding and coiled-coil domain 2 2.61912
RNF25 ring finger protein 25 2.61235
HLA-A major histocompatibility complex, class I, A 2.61079
SAMD9 sterile alpha motif domain containing 9 2.59328
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.59143
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.58906
WNT5B wingless-type MMTV integration site family, member 5B 2.58497
ITPRID2 ITPR interacting domain containing 2 2.58428
SIPA1 signal-induced proliferation-associated 1 2.58267
KIF3B kinesin family member 3B 2.58252
ERCC1 excision repair cross-complementation group 1 2.58204
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.57826
TCEA2 transcription elongation factor A (SII), 2 2.57638
NPC1 Niemann-Pick disease, type C1 2.57043
CANT1 calcium activated nucleotidase 1 2.56595
CYB5R3 cytochrome b5 reductase 3 2.56178
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 2.56047
WNT7A wingless-type MMTV integration site family, member 7A 2.55951
ARSA arylsulfatase A 2.55542
AMN amnion associated transmembrane protein 2.54922
PPIC peptidylprolyl isomerase C (cyclophilin C) 2.52963
RABAC1 Rab acceptor 1 (prenylated) 2.52835
RUBCN rubicon autophagy regulator 2.52738
GBA1 glucosylceramidase beta 1 2.52615
CYB5R1 cytochrome b5 reductase 1 2.51676
AEN apoptosis enhancing nuclease 2.51572
INPPL1 inositol polyphosphate phosphatase-like 1 2.51119
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 2.51048
ATF3 activating transcription factor 3 2.51039
TSPAN6 tetraspanin 6 2.5049
SIRT7 sirtuin 7 2.49962
TSPAN14 tetraspanin 14 2.49918
CTRB2 chymotrypsinogen B2 2.49745
GABARAPL1 GABA(A) receptor-associated protein like 1 2.49503
LGALS1 lectin, galactoside-binding, soluble, 1 2.49457
CDK7 cyclin-dependent kinase 7 2.48791
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 2.48534
MED15 mediator complex subunit 15 2.48414
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 2.48066
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.47887
CLDN7 claudin 7 2.47797
CAMTA2 calmodulin binding transcription activator 2 2.47568
ATP5F1E ATP synthase F1 subunit epsilon 2.47409
DYNLT3 dynein, light chain, Tctex-type 3 2.47406
ATP13A2 ATPase type 13A2 2.47337
ERCC6 excision repair cross-complementation group 6 2.47202
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.46433
HCFC2 host cell factor C2 2.46379
OXSR1 oxidative stress responsive 1 2.45736
SAP30BP SAP30 binding protein 2.45517
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.45086
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.4474
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.4431
ACOT9 acyl-CoA thioesterase 9 2.43807
ADAM8 ADAM metallopeptidase domain 8 2.43783
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.43218
TMEM140 transmembrane protein 140 2.42776
INF2 inverted formin, FH2 and WH2 domain containing 2.42733
UPK1B uroplakin 1B 2.42639
OSBPL2 oxysterol binding protein-like 2 2.42541
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 2.42171
MYL9 myosin, light chain 9, regulatory 2.42135
WSB2 WD repeat and SOCS box containing 2 2.42091
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.41673
MPPE1 metallophosphoesterase 1 2.41653
KLK1 kallikrein 1 2.41416
PRR13 proline rich 13 2.40979
TSPAN1 tetraspanin 1 2.40851
INKA2 inka box actin regulator 2 2.40625
BAX BCL2-associated X protein 2.40578
WBP1L WW domain binding protein 1-like 2.40081
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 2.39474
RPP38 ribonuclease P/MRP 38kDa subunit 2.38987
SLC16A6 solute carrier family 16, member 6 2.37684
DAPL1 death associated protein-like 1 2.3761
PPP4R1 protein phosphatase 4, regulatory subunit 1 2.37461
TMEM127 transmembrane protein 127 2.36719
STXBP2 syntaxin binding protein 2 2.36383
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.3606
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 2.35861
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.3512
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.34905
PYCARD PYD and CARD domain containing 2.34862
CASZ1 castor zinc finger 1 2.34436
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 2.33707
ETHE1 ethylmalonic encephalopathy 1 2.33675
ARHGAP1 Rho GTPase activating protein 1 2.33571
SP100 SP100 nuclear antigen 2.33507
PRSS22 protease, serine, 22 2.33471
OSTF1 osteoclast stimulating factor 1 2.32822
SDC4 syndecan 4 2.32751
AP1B1 adaptor-related protein complex 1, beta 1 subunit 2.32682
CTAGE8 CTAGE family, member 8 2.31654
PARP12 poly (ADP-ribose) polymerase family, member 12 2.31619
CADM1 cell adhesion molecule 1 2.31313
ANXA4 annexin A4 2.3121
CALCOCO1 calcium binding and coiled-coil domain 1 2.31191
TMEM184B transmembrane protein 184B 2.30949
CYTH1 cytohesin 1 2.30793
STAT1 signal transducer and activator of transcription 1, 91kDa 2.30578
BCL2L1 BCL2-like 1 2.30494
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.30372
FKBP1B FK506 binding protein 1B, 12.6 kDa 2.29712
ESS2 ess-2 splicing factor homolog 2.29383
ASL argininosuccinate lyase 2.29082
SERINC5 serine incorporator 5 2.28934
CSRP1 cysteine and glycine-rich protein 1 2.28932
KRT33A keratin 33A, type I 2.28662
MICA MHC class I polypeptide-related sequence A 2.28564
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.28548
ECM1 extracellular matrix protein 1 2.27537
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 2.27484
TJP1 tight junction protein 1 2.27264
DDR1 discoidin domain receptor tyrosine kinase 1 2.26616
LIMK2 LIM domain kinase 2 2.26014
DUSP10 dual specificity phosphatase 10 2.25397
BBC3 BCL2 binding component 3 2.25131
USP6NL USP6 N-terminal like 2.24542
DEPDC5 DEP domain containing 5 2.23965
IER3 immediate early response 3 2.23933
CTF1 cardiotrophin 1 2.23166
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.23123
ADIPOR2 adiponectin receptor 2 2.22868
CCDC90B coiled-coil domain containing 90B 2.22393
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 2.22147
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.22008
PSD4 pleckstrin and Sec7 domain containing 4 2.21991
LSR lipolysis stimulated lipoprotein receptor 2.21825
TRIM21 tripartite motif containing 21 2.21802
RIGI RNA sensor RIG-I 2.21754
LOC127933115 uncharacterized LOC127933115 2.21477
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 2.21474
SYNC syncoilin, intermediate filament protein 2.2101
DGKA diacylglycerol kinase, alpha 80kDa 2.20913
CD82 CD82 molecule 2.20743
TSG101 tumor susceptibility 101 2.20737
CDR2L cerebellar degeneration-related protein 2-like 2.19992
CNRIP1 cannabinoid receptor interacting protein 1 2.1996
TOM1L2 target of myb1-like 2 (chicken) 2.19609
SFXN3 sideroflexin 3 2.19481
ANXA11 annexin A11 2.19421
ELF4 E74-like factor 4 (ets domain transcription factor) 2.18998
CD37 CD37 molecule 2.18984
ARSD arylsulfatase D 2.18894
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.18196
SLC75A1 solute carrier family 75 member 1 2.17603
LLGL2 lethal giant larvae homolog 2 (Drosophila) 2.1745
FOSL1 FOS-like antigen 1 2.16994
GPRC5A G protein-coupled receptor, class C, group 5, member A 2.16694
AVPI1 arginine vasopressin-induced 1 2.16602
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.16601
HSPB11 heat shock protein family B (small), member 11 2.16469
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 2.16354
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.16141
HLA-C major histocompatibility complex, class I, C 2.15837
CHPF2 chondroitin polymerizing factor 2 2.15578
CCND3 cyclin D3 2.15519
ATOSB atos homolog B 2.15326
ABHD8 abhydrolase domain containing 8 2.15305
BAG3 BCL2-associated athanogene 3 2.15292
HBEGF heparin-binding EGF-like growth factor 2.15243
JUND jun D proto-oncogene 2.1493
RNF11 ring finger protein 11 2.14811
CCPG1 cell cycle progression 1 2.14793
PIEZO1 piezo-type mechanosensitive ion channel component 1 2.14327
KRT8 keratin 8, type II 2.14179
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.13392
CELA3B chymotrypsin-like elastase family, member 3B 2.13242
ICAM3 intercellular adhesion molecule 3 2.12768
NECAP2 NECAP endocytosis associated 2 2.12587
ZFP36 ZFP36 ring finger protein 2.12581
PDK2 pyruvate dehydrogenase kinase, isozyme 2 2.12452
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.1187
CSNK1E casein kinase 1, epsilon 2.11847
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.10905
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 2.10563
RND1 Rho family GTPase 1 2.10497
TESK2 testis-specific kinase 2 2.10408
BCAS4 breast carcinoma amplified sequence 4 2.10375
NCDN neurochondrin 2.10237
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.101
ITGB4 integrin, beta 4 2.09768
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.09692
BEST1 bestrophin 1 2.09653
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.09524
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.09512
SLC44A4 solute carrier family 44, member 4 2.09306
HLA-B major histocompatibility complex, class I, B 2.08806
TRPM4 transient receptor potential cation channel, subfamily M, member 4 2.08757
ISG20 interferon stimulated exonuclease gene 20kDa 2.08441
FAM13B family with sequence similarity 13, member B 2.08209
CCDC186 coiled-coil domain containing 186 2.08179
CCL20 chemokine (C-C motif) ligand 20 2.07865
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 2.07835
ATG2A autophagy related 2A 2.07702
VILL villin-like 2.07592
EMP1 epithelial membrane protein 1 2.07572
ARMCX6 armadillo repeat containing, X-linked 6 2.07295
GLTP glycolipid transfer protein 2.0697
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.06643
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.06329
ABI1 abl-interactor 1 2.06135
CCNE1 cyclin E1 2.06117
MISP mitotic spindle positioning 2.05673
ATG4A autophagy related 4A, cysteine peptidase 2.05551
TERF2IP telomeric repeat binding factor 2, interacting protein 2.05551
MAN2A1 mannosidase, alpha, class 2A, member 1 2.05343
RTF2 replication termination factor 2 2.05187
DNMBP dynamin binding protein 2.04945
EMC7 ER membrane protein complex subunit 7 2.04849
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.04785
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 2.04766
PPME1 protein phosphatase methylesterase 1 2.04719
GNAS GNAS complex locus 2.04639
OCLN occludin 2.04512
ATP9A ATPase, class II, type 9A 2.04473
MCOLN1 mucolipin 1 2.04177
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.04132
LYPD3 LY6/PLAUR domain containing 3 2.03926
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 2.03881
PLEK2 pleckstrin 2 2.03844
DAPK3 death-associated protein kinase 3 2.03746
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 2.03628
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 2.03598
DNASE1L1 deoxyribonuclease I-like 1 2.0347
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 2.03459
GGTLC1 gamma-glutamyltransferase light chain 1 2.03441
BIRC7 baculoviral IAP repeat containing 7 2.03404
ERBB3 erb-b2 receptor tyrosine kinase 3 2.03394
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 2.02895
PRAF2 PRA1 domain family, member 2 2.02862
WDR47 WD repeat domain 47 2.02253
ARMCX3 armadillo repeat containing, X-linked 3 2.02227
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.02002
MYO1E myosin IE 2.01932
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.01821
FES FES proto-oncogene, tyrosine kinase 2.01663
FBXO2 F-box protein 2 2.01592
NEK7 NIMA-related kinase 7 2.015
SIN3B SIN3 transcription regulator family member B 2.01475
CHP2 calcineurin-like EF-hand protein 2 2.01419
CTSV cathepsin V 2.0128
RAB11FIP5 RAB11 family interacting protein 5 (class I) 2.01167
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.01047
HFE hemochromatosis 2.01012
TOLLIP toll interacting protein 2.00426
RABEP2 rabaptin, RAB GTPase binding effector protein 2 2.00332
NRIP1 nuclear receptor interacting protein 1 2.00231
FASN fatty acid synthase 2.00166

decreased expression

Symbol Name Standardized Value
PSRC1 proline/serine-rich coiled-coil 1 -10.0
CDC20 cell division cycle 20 -10.0
UBE2C ubiquitin-conjugating enzyme E2C -9.90239
KIF20A kinesin family member 20A -9.37069
CCNB2 cyclin B2 -9.31891
PLK1 polo-like kinase 1 -9.11183
NLRP4 NLR family, pyrin domain containing 4 -8.56769
KIF14 kinesin family member 14 -8.5428
TOP2A topoisomerase (DNA) II alpha 170kDa -7.63471
BIRC5 baculoviral IAP repeat containing 5 -7.21574
LBR lamin B receptor -7.16445
CCNA2 cyclin A2 -7.09692
NCAPD2 non-SMC condensin I complex, subunit D2 -6.97346
DEPDC1 DEP domain containing 1 -6.31965
CCNB1 cyclin B1 -6.31488
CENPA centromere protein A -6.13567
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -6.12869
MSRA methionine sulfoxide reductase A -5.96695
TSEN2 TSEN2 tRNA splicing endonuclease subunit -5.80452
KIF4A kinesin family member 4A -5.77052
FBXO5 F-box protein 5 -5.7588
PIMREG PICALM interacting mitotic regulator -5.5605
AURKB aurora kinase B -5.48291
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -5.47678
HMMR hyaluronan-mediated motility receptor (RHAMM) -5.40266
CDC25B cell division cycle 25B -5.38002
AURKA aurora kinase A -5.29477
C1QBP complement component 1, q subcomponent binding protein -5.2463
CDK4 cyclin-dependent kinase 4 -5.22705
CDCA8 cell division cycle associated 8 -5.19677
NEK2 NIMA-related kinase 2 -5.13038
HJURP Holliday junction recognition protein -5.03322
NCAPH non-SMC condensin I complex, subunit H -4.97574
KIF23 kinesin family member 23 -4.95988
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -4.94693
OIP5 Opa interacting protein 5 -4.94227
BPHL biphenyl hydrolase-like (serine hydrolase) -4.94141
CD320 CD320 molecule -4.91203
CDCA3 cell division cycle associated 3 -4.87605
KIF11 kinesin family member 11 -4.86991
COG2 component of oligomeric golgi complex 2 -4.84055
NEIL3 nei endonuclease VIII-like 3 (E. coli) -4.8366
CDK1 cyclin-dependent kinase 1 -4.82003
TRAP1 TNF receptor-associated protein 1 -4.77948
SPC25 SPC25, NDC80 kinetochore complex component -4.77356
KIF15 kinesin family member 15 -4.59097
PBK PDZ binding kinase -4.58088
CETN3 centrin, EF-hand protein, 3 -4.42424
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -4.41399
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.37837
PARPBP PARP1 binding protein -4.30593
CDKN3 cyclin-dependent kinase inhibitor 3 -4.29426
KIF18A kinesin family member 18A -4.27563
HADH hydroxyacyl-CoA dehydrogenase -4.27433
ERCC6L excision repair cross-complementation group 6-like -4.26993
RPIA ribose 5-phosphate isomerase A -4.24267
MKI67 marker of proliferation Ki-67 -4.20196
MCM3 minichromosome maintenance complex component 3 -4.15327
LMNB1 lamin B1 -4.13152
SPAG5 sperm associated antigen 5 -4.04225
BLMH bleomycin hydrolase -3.99298
LAP3 leucine aminopeptidase 3 -3.98742
NDC80 NDC80 kinetochore complex component -3.97586
CDC25C cell division cycle 25C -3.96734
EBNA1BP2 EBNA1 binding protein 2 -3.95225
TTK TTK protein kinase -3.93808
RUVBL1 RuvB-like AAA ATPase 1 -3.92822
MTERF3 mitochondrial transcription termination factor 3 -3.91578
NUSAP1 nucleolar and spindle associated protein 1 -3.88213
SHCBP1 SHC SH2-domain binding protein 1 -3.86761
CENPF centromere protein F, 350/400kDa -3.85573
KIF18B kinesin family member 18B -3.83942
DBF4 DBF4 zinc finger -3.81118
CDCA4 cell division cycle associated 4 -3.80496
HMGB2 high mobility group box 2 -3.77331
ECT2 epithelial cell transforming 2 -3.76807
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.74336
PARP1 poly (ADP-ribose) polymerase 1 -3.73471
CKAP2 cytoskeleton associated protein 2 -3.73107
COASY CoA synthase -3.72876
BORA bora, aurora kinase A activator -3.67801
TACC3 transforming, acidic coiled-coil containing protein 3 -3.66463
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -3.65839
NFYB nuclear transcription factor Y, beta -3.65648
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -3.65638
CBR3 carbonyl reductase 3 -3.6516
HSPD1 heat shock 60kDa protein 1 (chaperonin) -3.63814
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.60298
ACOD1 aconitate decarboxylase 1 -3.60103
NT5DC2 5'-nucleotidase domain containing 2 -3.54894
RACGAP1 Rac GTPase activating protein 1 -3.54846
MRPL19 mitochondrial ribosomal protein L19 -3.54835
TROAP trophinin associated protein -3.5433
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.4424
EXO1 exonuclease 1 -3.44163
TPX2 TPX2, microtubule-associated -3.43355
SKA1 spindle and kinetochore associated complex subunit 1 -3.43343
CDC7 cell division cycle 7 -3.39385
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -3.37904
CADPS2 Ca++-dependent secretion activator 2 -3.35727
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.33908
PUS1 pseudouridylate synthase 1 -3.33783
TMEM109 transmembrane protein 109 -3.33188
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.32812
HEATR3 HEAT repeat containing 3 -3.30981
RFC3 replication factor C (activator 1) 3, 38kDa -3.28883
CENPE centromere protein E, 312kDa -3.26538
MRPS18B mitochondrial ribosomal protein S18B -3.25939
FIRRM FIGNL1 interacting regulator of recombination and mitosis -3.25175
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -3.23558
DET1 de-etiolated homolog 1 (Arabidopsis) -3.21702
GALE UDP-galactose-4-epimerase -3.20643
SPDL1 spindle apparatus coiled-coil protein 1 -3.20454
EMC8 ER membrane protein complex subunit 8 -3.19469
MRPS2 mitochondrial ribosomal protein S2 -3.16973
DNM1 dynamin 1 -3.16882
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -3.16755
MKKS McKusick-Kaufman syndrome -3.16512
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -3.1531
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -3.13145
DKC1 dyskeratosis congenita 1, dyskerin -3.10666
DDIT4 DNA-damage-inducible transcript 4 -3.08279
APIP APAF1 interacting protein -3.06058
RIDA reactive intermediate imine deaminase A homolog -3.03191
ISOC2 isochorismatase domain containing 2 -3.02575
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.0247
INTS14 integrator complex subunit 14 -3.01659
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -3.0144
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.00634
SF3A3 splicing factor 3a, subunit 3, 60kDa -3.00017
KIFC1 kinesin family member C1 -2.99407
GEMIN2 gem (nuclear organelle) associated protein 2 -2.98878
GTSE1 G-2 and S-phase expressed 1 -2.9865
PYCR1 pyrroline-5-carboxylate reductase 1 -2.98398
HMGN4 high mobility group nucleosomal binding domain 4 -2.97051
ENTR1 endosome associated trafficking regulator 1 -2.9472
ACOX2 acyl-CoA oxidase 2, branched chain -2.93092
CYCS cytochrome c, somatic -2.91564
CEP55 centrosomal protein 55kDa -2.91561
SSBP2 single-stranded DNA binding protein 2 -2.90548
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -2.90363
HEATR1 HEAT repeat containing 1 -2.89858
UBE2S ubiquitin-conjugating enzyme E2S -2.88944
GPD1L glycerol-3-phosphate dehydrogenase 1-like -2.88859
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.87242
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.86657
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.86402
CRMP1 collapsin response mediator protein 1 -2.86231
NUP37 nucleoporin 37kDa -2.85532
YEATS4 YEATS domain containing 4 -2.85433
EXOSC8 exosome component 8 -2.85138
NOP16 NOP16 nucleolar protein -2.84733
FANCC Fanconi anemia, complementation group C -2.84647
CKS2 CDC28 protein kinase regulatory subunit 2 -2.83884
RFXAP regulatory factor X-associated protein -2.83738
PARP2 poly (ADP-ribose) polymerase 2 -2.83626
REV1 REV1, polymerase (DNA directed) -2.81705
EPHB2 EPH receptor B2 -2.81558
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.81385
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.79854
CENPN centromere protein N -2.79791
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.79582
MCM10 minichromosome maintenance complex component 10 -2.78882
KIAA0586 KIAA0586 -2.77895
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.76702
TRIP13 thyroid hormone receptor interactor 13 -2.76643
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -2.76012
PRC1 protein regulator of cytokinesis 1 -2.75939
CBX3 chromobox homolog 3 -2.75112
NOP14 NOP14 nucleolar protein -2.73029
CHEK1 checkpoint kinase 1 -2.72572
PUM2 pumilio RNA-binding family member 2 -2.71866
RHOT1 ras homolog family member T1 -2.71498
CKS1B CDC28 protein kinase regulatory subunit 1B -2.7108
CDC45 cell division cycle 45 -2.71073
TSPAN3 tetraspanin 3 -2.70729
KIF22 kinesin family member 22 -2.70349
MNDA myeloid cell nuclear differentiation antigen -2.70138
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.70131
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.68742
PPA2 pyrophosphatase (inorganic) 2 -2.68564
MRPL58 mitochondrial ribosomal protein L58 -2.68377
PBX1 pre-B-cell leukemia homeobox 1 -2.67721
MRPL12 mitochondrial ribosomal protein L12 -2.67227
CCDC102B coiled-coil domain containing 102B -2.66895
MPHOSPH9 M-phase phosphoprotein 9 -2.66209
ANAPC10 anaphase promoting complex subunit 10 -2.66102
DHFR dihydrofolate reductase -2.62847
PIBF1 progesterone immunomodulatory binding factor 1 -2.62811
MPO myeloperoxidase -2.61548
GPHN gephyrin -2.61025
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.61021
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -2.60704
NUBP2 nucleotide binding protein 2 -2.60252
MRPL4 mitochondrial ribosomal protein L4 -2.6009
RXYLT1 ribitol xylosyltransferase 1 -2.59648
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -2.5902
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.59015
STOML2 stomatin (EPB72)-like 2 -2.58935
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.58545
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.58504
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -2.5795
ELANE elastase, neutrophil expressed -2.57873
ARB2A ARB2 cotranscriptional regulator A -2.56928
SNRPA small nuclear ribonucleoprotein polypeptide A -2.56925
TMPO thymopoietin -2.5672
WDHD1 WD repeat and HMG-box DNA binding protein 1 -2.56475
TRIM28 tripartite motif containing 28 -2.56397
TRMT5 tRNA methyltransferase 5 -2.56181
ZNF322 zinc finger protein 322 -2.56047
TUBGCP5 tubulin, gamma complex associated protein 5 -2.5595
VCAN versican -2.55775
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.5539
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.55356
NDC1 NDC1 transmembrane nucleoporin -2.55122
NSD2 nuclear receptor binding SET domain protein 2 -2.5503
PRMT3 protein arginine methyltransferase 3 -2.54832
PTTG1 pituitary tumor-transforming 1 -2.54687
GEMIN6 gem (nuclear organelle) associated protein 6 -2.5436
BBS10 Bardet-Biedl syndrome 10 -2.54339
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.54191
ORC6 origin recognition complex, subunit 6 -2.53872
GRPEL1 GrpE-like 1, mitochondrial (E. coli) -2.5369
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -2.53168
SNRPE small nuclear ribonucleoprotein polypeptide E -2.5293
CDC6 cell division cycle 6 -2.52438
HMGB3 high mobility group box 3 -2.51655
COPZ1 coatomer protein complex, subunit zeta 1 -2.5088
BCCIP BRCA2 and CDKN1A interacting protein -2.50872
STRA6 stimulated by retinoic acid 6 -2.5026
TBRG4 transforming growth factor beta regulator 4 -2.50256
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.49764
TMEM177 transmembrane protein 177 -2.49055
FAM200C family with sequence similarity 200 member C -2.48934
RAD23B RAD23 homolog B (S. cerevisiae) -2.48926
SETD6 SET domain containing 6 -2.48658
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -2.48569
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.48466
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.48466
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -2.48408
TRIB2 tribbles pseudokinase 2 -2.47924
ARHGAP11A Rho GTPase activating protein 11A -2.47474
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.4727
TIPIN TIMELESS interacting protein -2.46732
E2F5 E2F transcription factor 5, p130-binding -2.46684
ZNF302 zinc finger protein 302 -2.46349
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.45569
NUP133 nucleoporin 133kDa -2.452
PSIP1 PC4 and SFRS1 interacting protein 1 -2.45165
MED27 mediator complex subunit 27 -2.45132
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.45104
NRF1 nuclear respiratory factor 1 -2.4502
TKT transketolase -2.44961
SMC4 structural maintenance of chromosomes 4 -2.44886
AK4 adenylate kinase 4 -2.44524
ZNF83 zinc finger protein 83 -2.44397
VRK1 vaccinia related kinase 1 -2.43506
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -2.42739
CPAP centrosome assembly and centriole elongation protein -2.41043
G6PC3 glucose 6 phosphatase, catalytic, 3 -2.40652
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -2.40482
OARD1 O-acyl-ADP-ribose deacylase 1 -2.40476
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -2.40408
NTHL1 nth endonuclease III-like 1 (E. coli) -2.3956
MDC1 mediator of DNA-damage checkpoint 1 -2.39552
PLK4 polo-like kinase 4 -2.3923
MSH6 mutS homolog 6 -2.39126
LIAS lipoic acid synthetase -2.38291
CLOCK clock circadian regulator -2.38052
CHRDL1 chordin-like 1 -2.37866
TRIM27 tripartite motif containing 27 -2.37851
RPP40 ribonuclease P/MRP 40kDa subunit -2.37746
NIPSNAP2 nipsnap homolog 2 -2.3753
HDAC2 histone deacetylase 2 -2.37288
ZNF280D zinc finger protein 280D -2.37099
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.3697
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -2.36765
TLCD3A TLC domain containing 3A -2.36722
GPSM2 G-protein signaling modulator 2 -2.36681
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.36547
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.36475
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -2.35908
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -2.3569
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -2.35637
RSBN1 round spermatid basic protein 1 -2.35266
CISD1 CDGSH iron sulfur domain 1 -2.34875
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -2.34722
PHOSPHO2-KLHL23 PHOSPHO2-KLHL23 readthrough -2.34358
GGT5 gamma-glutamyltransferase 5 -2.34143
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.33573
DPYD dihydropyrimidine dehydrogenase -2.32808
RABEPK Rab9 effector protein with kelch motifs -2.32528
BRD7 bromodomain containing 7 -2.32349
C1GALT1C1 C1GALT1-specific chaperone 1 -2.3225
RNASE6 ribonuclease, RNase A family, k6 -2.32019
NR2F1 nuclear receptor subfamily 2, group F, member 1 -2.31614
COQ3 coenzyme Q3 methyltransferase -2.3161
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -2.31499
RPA3 replication protein A3, 14kDa -2.31495
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.31311
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.31295
AUH AU RNA binding protein/enoyl-CoA hydratase -2.30934
CTDNEP1 CTD nuclear envelope phosphatase 1 -2.30895
EID1 EP300 interacting inhibitor of differentiation 1 -2.30751
HSPA8 heat shock 70kDa protein 8 -2.30683
ZNF184 zinc finger protein 184 -2.30313
ILF2 interleukin enhancer binding factor 2 -2.30056
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -2.28311
TBP TATA box binding protein -2.28264
BRIX1 BRX1, biogenesis of ribosomes -2.27848
TMEM176A transmembrane protein 176A -2.27754
FGL2 fibrinogen-like 2 -2.27535
PKP4 plakophilin 4 -2.27498
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.27106
BRD3 bromodomain containing 3 -2.26957
MSH5 mutS homolog 5 -2.2678
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -2.26714
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -2.26701
CEP83 centrosomal protein 83kDa -2.26641
F13A1 coagulation factor XIII, A1 polypeptide -2.26492
ANKRD10 ankyrin repeat domain 10 -2.26488
RCC1 regulator of chromosome condensation 1 -2.26056
IL33 interleukin 33 -2.26052
UNC50 unc-50 homolog (C. elegans) -2.26024
RNF146 ring finger protein 146 -2.25747
TLR2 toll-like receptor 2 -2.25235
CTSO cathepsin O -2.2467
ENOX1 ecto-NOX disulfide-thiol exchanger 1 -2.24664
ZNF606 zinc finger protein 606 -2.24473
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.24407
COMMD10 COMM domain containing 10 -2.24323
CEP112 centrosomal protein 112kDa -2.23926
RBMX RNA binding motif protein, X-linked -2.23749
TFB2M transcription factor B2, mitochondrial -2.23531
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.23353
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -2.2325
MAP2K5 mitogen-activated protein kinase kinase 5 -2.2314
MPHOSPH6 M-phase phosphoprotein 6 -2.22904
RPGRIP1L RPGRIP1-like -2.22213
THAP11 THAP domain containing 11 -2.21936
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.21925
CCNH cyclin H -2.21328
SAP30 Sin3A-associated protein, 30kDa -2.21248
CLEC5A C-type lectin domain family 5, member A -2.21172
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.21101
NPDC1 neural proliferation, differentiation and control, 1 -2.20939
ECPAS Ecm29 proteasome adaptor and scaffold -2.20893
CLIC2 chloride intracellular channel 2 -2.20884
ATAD2 ATPase family, AAA domain containing 2 -2.20822
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like -2.20665
SMN2 survival of motor neuron 2, centromeric -2.20622
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.20585
CTSG cathepsin G -2.20571
UXT ubiquitously-expressed, prefoldin-like chaperone -2.20571
ICE1 interactor of little elongation complex ELL subunit 1 -2.20193
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -2.201
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -2.20094
CFI complement factor I -2.19847
CTCF CCCTC-binding factor (zinc finger protein) -2.19659
ELP4 elongator acetyltransferase complex subunit 4 -2.19629
MTIF2 mitochondrial translational initiation factor 2 -2.19539
SRPK1 SRSF protein kinase 1 -2.19077
DPH5 diphthamide biosynthesis 5 -2.19024
FXN frataxin -2.18964
FAM216A family with sequence similarity 216, member A -2.18725
PALS2 protein associated with LIN7 2, MAGUK p55 family member -2.18703
DPH2 DPH2 homolog (S. cerevisiae) -2.18592
HSPE1 heat shock 10kDa protein 1 -2.18367
ADGRA2 adhesion G protein-coupled receptor A2 -2.18326
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.18273
AUNIP aurora kinase A and ninein interacting protein -2.18242
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -2.18072
KAT8 K(lysine) acetyltransferase 8 -2.17945
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.17863
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.17574
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.17431
E2F8 E2F transcription factor 8 -2.17269
ZNF16 zinc finger protein 16 -2.17124
SET SET nuclear proto-oncogene -2.16877
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.16747
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -2.16666
PDHB pyruvate dehydrogenase (lipoamide) beta -2.16103
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -2.15956
PFAS phosphoribosylformylglycinamidine synthase -2.15942
BZW2 basic leucine zipper and W2 domains 2 -2.1592
PCBP1 poly(rC) binding protein 1 -2.15499
BICRAL BICRA like chromatin remodeling complex associated protein -2.1537
GALP galanin-like peptide -2.15348
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.15265
THADA thyroid adenoma associated -2.15204
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.15183
ATP5ME ATP synthase membrane subunit e -2.15052
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.15008
CREG1 cellular repressor of E1A-stimulated genes 1 -2.1484
NFIL3 nuclear factor, interleukin 3 regulated -2.14655
DPY19L1 dpy-19-like 1 (C. elegans) -2.14439
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.14382
SUMF2 sulfatase modifying factor 2 -2.14267
DNA2 DNA replication helicase/nuclease 2 -2.14186
LOC128966622 putative protein N-methyltransferase FAM86B2 -2.14131
PXMP2 peroxisomal membrane protein 2, 22kDa -2.13972
ACTL6A actin-like 6A -2.13832
HAUS7 HAUS augmin-like complex, subunit 7 -2.13717
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.13283
CXCL12 chemokine (C-X-C motif) ligand 12 -2.13166
PPA1 pyrophosphatase (inorganic) 1 -2.12926
LOXL1 lysyl oxidase-like 1 -2.12491
RTL8A retrotransposon Gag like 8A -2.12346
WDR82 WD repeat domain 82 -2.11897
MEOX1 mesenchyme homeobox 1 -2.11895
ENOX2 ecto-NOX disulfide-thiol exchanger 2 -2.11557
DCK deoxycytidine kinase -2.1137
NOL4 nucleolar protein 4 -2.11187
FBL fibrillarin -2.10737
USP39 ubiquitin specific peptidase 39 -2.10568
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -2.10468
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -2.10037
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -2.09899
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.09779
SORD sorbitol dehydrogenase -2.09756
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.09713
ARHGAP9 Rho GTPase activating protein 9 -2.09393
BOLA1 bolA family member 1 -2.09393
PROSER1 proline and serine rich 1 -2.09377
SELENOP selenoprotein P -2.09335
ZNF318 zinc finger protein 318 -2.09053
DTWD1 DTW domain containing 1 -2.08989
FTO fat mass and obesity associated -2.08652
TWNK twinkle mtDNA helicase -2.08565
GARRE1 granule associated Rac and RHOG effector 1 -2.08313
CEP76 centrosomal protein 76kDa -2.08132
PSAT1 phosphoserine aminotransferase 1 -2.07953
PARG poly (ADP-ribose) glycohydrolase -2.07922
FASTKD3 FAST kinase domains 3 -2.07863
TMEM176B transmembrane protein 176B -2.0781
RIOX2 ribosomal oxygenase 2 -2.07343
IL7R interleukin 7 receptor -2.06526
DLAT dihydrolipoamide S-acetyltransferase -2.06522
PUS7 pseudouridylate synthase 7 (putative) -2.06428
MCTS1 malignant T cell amplified sequence 1 -2.06226
PAK1IP1 PAK1 interacting protein 1 -2.05909
PHF2 PHD finger protein 2 -2.05866
NCAPG2 non-SMC condensin II complex, subunit G2 -2.05825
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -2.05691
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -2.05396
TOP2B topoisomerase (DNA) II beta 180kDa -2.05148
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.04821
SNRPF small nuclear ribonucleoprotein polypeptide F -2.04632
RAD50 RAD50 homolog (S. cerevisiae) -2.046
NELFA negative elongation factor complex member A -2.04593
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.04564
CLEC10A C-type lectin domain family 10, member A -2.04453
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.04392
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.0397
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -2.0377
ARHGAP19 Rho GTPase activating protein 19 -2.03478
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -2.03247
AHCTF1 AT hook containing transcription factor 1 -2.02604
NPM3 nucleophosmin/nucleoplasmin 3 -2.02589
PGM1 phosphoglucomutase 1 -2.02574
WDR74 WD repeat domain 74 -2.02194
TPK1 thiamin pyrophosphokinase 1 -2.01942
DNAAF2 dynein, axonemal, assembly factor 2 -2.01654
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -2.01605
OBI1 ORC ubiquitin ligase 1 -2.01542
ETAA1 Ewing tumor-associated antigen 1 -2.01466
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -2.01413
CUL1 cullin 1 -2.01353
JADE1 jade family PHD finger 1 -2.00919
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.00675
MEX3D mex-3 RNA binding family member D -2.00567
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -2.00545
MRS2 MRS2 magnesium transporter -2.0044
MRPL3 mitochondrial ribosomal protein L3 -2.0039