CRCGN016_MCF10A.WT.HP_24H:C02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description pcb126 3.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:C02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 5.51282
TBX2 T-box 2 3.85776
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.936
MAMLD1 mastermind-like domain containing 1 2.69288
SPAG4 sperm associated antigen 4 2.60819
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.52166
ALAS1 5'-aminolevulinate synthase 1 2.3284
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.28678
E2F2 E2F transcription factor 2 2.19201
GATA2 GATA binding protein 2 2.09354
GGT5 gamma-glutamyltransferase 5 2.01087

decreased expression

Symbol Name Standardized Value
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.58142
TLCD3A TLC domain containing 3A -3.29313
MSMO1 methylsterol monooxygenase 1 -3.29155
C2CD5 C2 calcium-dependent domain containing 5 -2.91952
GDF15 growth differentiation factor 15 -2.66807
CD58 CD58 molecule -2.63351
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.3168
LZTFL1 leucine zipper transcription factor-like 1 -2.28969
PRCP prolylcarboxypeptidase (angiotensinase C) -2.24111
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.20901
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.08915
S100A8 S100 calcium binding protein A8 -2.05284
PMM2 phosphomannomutase 2 -2.04935