CRCGN016_MCF10A.WT.HP_24H:C03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description pcb126 1.11 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:C03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.45105
IGHMBP2 immunoglobulin mu binding protein 2 4.36271
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 3.75846
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.74436
E2F2 E2F transcription factor 2 3.29491
COMP cartilage oligomeric matrix protein 3.03121
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.99771
ADAT1 adenosine deaminase, tRNA-specific 1 2.85354
PECR peroxisomal trans-2-enoyl-CoA reductase 2.73986
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.73246
MCUR1 mitochondrial calcium uniporter regulator 1 2.69876
FOS FBJ murine osteosarcoma viral oncogene homolog 2.46949
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.44221
MOK MOK protein kinase 2.3898
ATG101 autophagy related 101 2.32117
DHDDS dehydrodolichyl diphosphate synthase 2.18137
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 2.15359
BNC1 basonuclin 1 2.09973
CGRRF1 cell growth regulator with ring finger domain 1 2.0842
GRAPL GRB2-related adaptor protein-like 2.0832
IL24 interleukin 24 2.03841
MUL1 mitochondrial E3 ubiquitin protein ligase 1 2.03833
FBXL8 F-box and leucine-rich repeat protein 8 2.03584

decreased expression

Symbol Name Standardized Value
CDC45 cell division cycle 45 -3.72189
NPDC1 neural proliferation, differentiation and control, 1 -3.06704
CANT1 calcium activated nucleotidase 1 -2.91326
THAP11 THAP domain containing 11 -2.81797
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.72121
CUL4B cullin 4B -2.69911
KDM3A lysine (K)-specific demethylase 3A -2.65454
RNF167 ring finger protein 167 -2.64237
OXA1L oxidase (cytochrome c) assembly 1-like -2.5628
ANXA2 annexin A2 -2.47006
VDAC1 voltage-dependent anion channel 1 -2.45027
XPO7 exportin 7 -2.09757
PUF60 poly-U binding splicing factor 60KDa -2.08813