| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | indirubin 33.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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77 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:C05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS3 | integrator complex subunit 3 | 4.97635 |
| HMOX1 | heme oxygenase 1 | 4.46177 |
| SPAG4 | sperm associated antigen 4 | 4.43984 |
| TBX2 | T-box 2 | 3.80578 |
| PRKCD | protein kinase C, delta | 3.35985 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 3.29464 |
| AGR2 | anterior gradient 2 | 3.22766 |
| SIRT3 | sirtuin 3 | 3.09173 |
| MAP1S | microtubule-associated protein 1S | 2.72639 |
| FBXO17 | F-box protein 17 | 2.69546 |
| IL1B | interleukin 1, beta | 2.68322 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 2.66676 |
| RIC8A | RIC8 guanine nucleotide exchange factor A | 2.59028 |
| CHMP1A | charged multivesicular body protein 1A | 2.54507 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.53944 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 2.51387 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.50994 |
| HRAS | Harvey rat sarcoma viral oncogene homolog | 2.4884 |
| CFAP298 | cilia and flagella associated protein 298 | 2.43451 |
| PIH1D1 | PIH1 domain containing 1 | 2.41407 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.39923 |
| MRPL30 | mitochondrial ribosomal protein L30 | 2.3738 |
| HOXC4 | homeobox C4 | 2.3482 |
| RPN1 | ribophorin I | 2.28338 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 2.24773 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.24084 |
| CFAP69 | cilia and flagella associated protein 69 | 2.2234 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.17579 |
| TAOK1 | TAO kinase 1 | 2.17237 |
| WDR19 | WD repeat domain 19 | 2.14433 |
| CCDC85B | coiled-coil domain containing 85B | 2.12682 |
| TPD52L2 | tumor protein D52-like 2 | 2.11907 |
| PCOLCE | procollagen C-endopeptidase enhancer | 2.11649 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | 2.08531 |
| ULBP2 | UL16 binding protein 2 | 2.0726 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | 2.05613 |
| CCL13 | chemokine (C-C motif) ligand 13 | 2.02514 |
| RASSF7 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 | 2.02234 |
| HOXA3 | homeobox A3 | 2.00657 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.58678 |
| LYPLA1 | lysophospholipase I | -4.41154 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -4.37894 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.93823 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.79052 |
| TLK2 | tousled-like kinase 2 | -3.60119 |
| MACF1 | microtubule-actin crosslinking factor 1 | -2.80578 |
| HTN1 | histatin 1 | -2.7452 |
| DUSP6 | dual specificity phosphatase 6 | -2.74177 |
| TCTA | T-cell leukemia translocation altered | -2.60796 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -2.58557 |
| AQP5 | aquaporin 5 | -2.51248 |
| LYPLA1-TCEA1 | LYPLA1-TCEA1 readthrough | -2.37225 |
| CASC3 | cancer susceptibility candidate 3 | -2.3317 |
| ANKRD10 | ankyrin repeat domain 10 | -2.32454 |
| DEFA3 | defensin, alpha 3, neutrophil-specific | -2.26768 |
| TSTD2 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 | -2.25914 |
| PRRC1 | proline-rich coiled-coil 1 | -2.23952 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.23805 |
| ELP3 | elongator acetyltransferase complex subunit 3 | -2.22987 |
| SUN2 | Sad1 and UNC84 domain containing 2 | -2.22274 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) | -2.22035 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | -2.20917 |
| PRKCH | protein kinase C, eta | -2.20836 |
| CDK20 | cyclin-dependent kinase 20 | -2.20084 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -2.18077 |
| MBNL3 | muscleblind-like splicing regulator 3 | -2.16979 |
| HTN3 | histatin 3 | -2.15672 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit | -2.13508 |
| TRAP1 | TNF receptor-associated protein 1 | -2.11715 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.07103 |
| CALML5 | calmodulin-like 5 | -2.0581 |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 | -2.05801 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | -2.04002 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -2.02846 |
| AK4 | adenylate kinase 4 | -2.0225 |
| GOLGA7 | golgin A7 | -2.01092 |
| MFSD6 | major facilitator superfamily domain containing 6 | -2.00837 |
