CRCGN016_MCF10A.WT.HP_24H:C09 Gene Set
Genes
48 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:C09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
4.65552
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
4.31296
|
|
ANO10
|
anoctamin 10
|
4.07524
|
|
DHRS2
|
dehydrogenase/reductase (SDR family) member 2
|
3.78926
|
|
GATA2
|
GATA binding protein 2
|
3.6232
|
|
TBX2
|
T-box 2
|
3.5372
|
|
HDGFL3
|
HDGF like 3
|
3.39024
|
|
PDLIM1
|
PDZ and LIM domain 1
|
3.12381
|
|
TXNRD1
|
thioredoxin reductase 1
|
3.11034
|
|
IGHMBP2
|
immunoglobulin mu binding protein 2
|
3.05305
|
|
FHL2
|
four and a half LIM domains 2
|
2.90842
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.85793
|
|
SMAD3
|
SMAD family member 3
|
2.84706
|
|
HMOX1
|
heme oxygenase 1
|
2.51034
|
|
SERPINE1
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
|
2.38964
|
|
FZD1
|
frizzled class receptor 1
|
2.37502
|
|
RPL39L
|
ribosomal protein L39-like
|
2.33016
|
|
HOXA5
|
homeobox A5
|
2.31696
|
|
STX1A
|
syntaxin 1A (brain)
|
2.30134
|
|
MINDY2
|
MINDY lysine 48 deubiquitinase 2
|
2.26516
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.26402
|
|
GCLM
|
glutamate-cysteine ligase, modifier subunit
|
2.264
|
|
CTSL
|
cathepsin L
|
2.25233
|
|
BRAF
|
B-Raf proto-oncogene, serine/threonine kinase
|
2.17211
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
2.14258
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.10556
|
|
CHST11
|
carbohydrate (chondroitin 4) sulfotransferase 11
|
2.01523
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-5.0151
|
|
CAB39
|
calcium binding protein 39
|
-4.06048
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-4.0233
|
|
CREB1
|
cAMP responsive element binding protein 1
|
-3.86133
|
|
DCK
|
deoxycytidine kinase
|
-3.44334
|
|
S100A4
|
S100 calcium binding protein A4
|
-3.20308
|
|
PRR15L
|
proline rich 15-like
|
-3.14771
|
|
ARID4B
|
AT rich interactive domain 4B (RBP1-like)
|
-3.11971
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.88705
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.73822
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.60317
|
|
IPO13
|
importin 13
|
-2.51598
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
-2.50073
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.27589
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
-2.16285
|
|
ADORA3
|
adenosine A3 receptor
|
-2.14305
|
|
PRSS8
|
protease, serine, 8
|
-2.08938
|
|
CCND2
|
cyclin D2
|
-2.07315
|
|
NFIL3
|
nuclear factor, interleukin 3 regulated
|
-2.05105
|
|
RAB25
|
RAB25, member RAS oncogene family
|
-2.03161
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.01392
|
