CRCGN016_MCF10A.WT.HP_24H:C15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dieldrin 11.39 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

25 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:C15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCR4 chemokine (C-X-C motif) receptor 4 4.38013
PPARG peroxisome proliferator-activated receptor gamma 3.9603
HBA1 hemoglobin, alpha 1 3.4942
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.25037
ADGRE5 adhesion G protein-coupled receptor E5 3.08453
WIF1 WNT inhibitory factor 1 2.36713
CCNA1 cyclin A1 2.35171
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.28299
TBXA2R thromboxane A2 receptor 2.27826
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.09045
FABP4 fatty acid binding protein 4, adipocyte 2.02398

decreased expression

Symbol Name Standardized Value
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.48026
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -4.02604
ZDHHC6 zinc finger, DHHC-type containing 6 -3.9378
ARID4B AT rich interactive domain 4B (RBP1-like) -3.89221
BASP1 brain abundant, membrane attached signal protein 1 -3.86379
GDF15 growth differentiation factor 15 -3.50093
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.14572
MSMO1 methylsterol monooxygenase 1 -2.94178
ALDOC aldolase C, fructose-bisphosphate -2.68676
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.44926
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.27935
TRIB3 tribbles pseudokinase 3 -2.23746
KIAA0232 KIAA0232 -2.12131
RAI14 retinoic acid induced 14 -2.04012