CRCGN016_MCF10A.WT.HP_24H:C16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-diaminotoluene 98.95 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

19 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:C16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.38841
IL1B interleukin 1, beta 3.33933
RTN2 reticulon 2 2.99208
RAB31 RAB31, member RAS oncogene family 2.79994
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.71239
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.6822
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.1601
CDPF1 cysteine-rich, DPF motif domain containing 1 2.05365

decreased expression

Symbol Name Standardized Value
PCCB propionyl CoA carboxylase, beta polypeptide -7.28517
CDC45 cell division cycle 45 -3.78569
PPIC peptidylprolyl isomerase C (cyclophilin C) -3.4931
GDF15 growth differentiation factor 15 -3.37301
TLCD3A TLC domain containing 3A -3.01287
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.99178
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.91154
PFN1 profilin 1 -2.65916
PCNA proliferating cell nuclear antigen -2.2175
ATF5 activating transcription factor 5 -2.04825
COPS7A COP9 signalosome subunit 7A -2.03794