CRCGN016_MCF10A.WT.HP_24H:C18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-diaminotoluene 10.99 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:C18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HYOU1 hypoxia up-regulated 1 3.13075
CGRRF1 cell growth regulator with ring finger domain 1 2.61191
PDLIM1 PDZ and LIM domain 1 2.50072
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.49928
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.15202

decreased expression

Symbol Name Standardized Value
BASP1 brain abundant, membrane attached signal protein 1 -4.83689
NT5DC2 5'-nucleotidase domain containing 2 -2.82528
GDF15 growth differentiation factor 15 -2.62121
RNF167 ring finger protein 167 -2.35642
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.31616
S100A8 S100 calcium binding protein A8 -2.29121
TEX10 testis expressed 10 -2.26122
PCNA proliferating cell nuclear antigen -2.12711