CRCGN016_MCF10A.WT.HP_24H:D02 Gene Set
Genes
46 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ALAS1
|
5'-aminolevulinate synthase 1
|
5.64065
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
4.61069
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.17304
|
|
E2F2
|
E2F transcription factor 2
|
4.09457
|
|
COMP
|
cartilage oligomeric matrix protein
|
3.42858
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.26459
|
|
SH3BP5
|
SH3-domain binding protein 5 (BTK-associated)
|
2.78555
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.78366
|
|
CERK
|
ceramide kinase
|
2.63327
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.4767
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.32149
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
2.23502
|
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
2.22019
|
|
AARSD1
|
alanyl-tRNA synthetase domain containing 1
|
2.17832
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
2.16696
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.1402
|
|
MOK
|
MOK protein kinase
|
2.11211
|
|
TTLL12
|
tubulin tyrosine ligase-like family member 12
|
2.02941
|
|
CTSL
|
cathepsin L
|
2.02684
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NCAPD2
|
non-SMC condensin I complex, subunit D2
|
-5.11696
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.08642
|
|
UBE2C
|
ubiquitin-conjugating enzyme E2C
|
-4.88789
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-4.63559
|
|
CDC20
|
cell division cycle 20
|
-4.25996
|
|
PLK1
|
polo-like kinase 1
|
-4.05403
|
|
HMG20B
|
high mobility group 20B
|
-3.75269
|
|
CCNB1
|
cyclin B1
|
-3.25173
|
|
RNF167
|
ring finger protein 167
|
-3.14731
|
|
TOP2A
|
topoisomerase (DNA) II alpha 170kDa
|
-3.14553
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.91366
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.87097
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.81226
|
|
RPA3
|
replication protein A3, 14kDa
|
-2.59033
|
|
KIF20A
|
kinesin family member 20A
|
-2.53145
|
|
KIF14
|
kinesin family member 14
|
-2.51065
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
-2.42721
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-2.42608
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
-2.40442
|
|
AURKA
|
aurora kinase A
|
-2.36142
|
|
TOPBP1
|
topoisomerase (DNA) II binding protein 1
|
-2.3482
|
|
THAP11
|
THAP domain containing 11
|
-2.21172
|
|
CENPA
|
centromere protein A
|
-2.10241
|
|
STMN1
|
stathmin 1
|
-2.07513
|
|
ASPM
|
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
|
-2.03819
|
|
POLR2C
|
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
|
-2.0206
|
|
CCNA2
|
cyclin A2
|
-2.01632
|
