| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-hydroxyphenazine 11.11 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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55 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STIMATE | STIM activating enhancer | 4.74692 |
| SESN1 | sestrin 1 | 4.0182 |
| BMP4 | bone morphogenetic protein 4 | 3.35362 |
| AGR2 | anterior gradient 2 | 3.33742 |
| MSRA | methionine sulfoxide reductase A | 3.23447 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 3.2242 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 3.03576 |
| OLFML2B | olfactomedin-like 2B | 2.92089 |
| ZNF589 | zinc finger protein 589 | 2.84069 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | 2.77018 |
| UVRAG | UV radiation resistance associated | 2.67302 |
| RSF1 | remodeling and spacing factor 1 | 2.4905 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 2.41777 |
| THAP12 | THAP domain containing 12 | 2.40617 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.31728 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 2.31626 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 | 2.16925 |
| MRPL48 | mitochondrial ribosomal protein L48 | 2.15936 |
| TGDS | TDP-glucose 4,6-dehydratase | 2.14092 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 2.10051 |
| GAB2 | GRB2-associated binding protein 2 | 2.09764 |
| MRPL18 | mitochondrial ribosomal protein L18 | 2.04995 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 2.04129 |
| HLA-DMB | major histocompatibility complex, class II, DM beta | 2.00873 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MSMO1 | methylsterol monooxygenase 1 | -5.44823 |
| DNM1L | dynamin 1-like | -4.98739 |
| RNF167 | ring finger protein 167 | -4.85888 |
| NGRN | neugrin, neurite outgrowth associated | -4.65579 |
| HAT1 | histone acetyltransferase 1 | -4.53084 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.34874 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.16487 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -4.10057 |
| YME1L1 | YME1-like 1 ATPase | -4.08015 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -3.65168 |
| CD320 | CD320 molecule | -3.57005 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -2.87684 |
| NT5M | 5',3'-nucleotidase, mitochondrial | -2.59675 |
| INTS14 | integrator complex subunit 14 | -2.53456 |
| MDFI | MyoD family inhibitor | -2.47549 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.47519 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 | -2.46616 |
| CLSTN3 | calsyntenin 3 | -2.40736 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.39085 |
| NISCH | nischarin | -2.36747 |
| BORCS8 | BLOC-1 related complex subunit 8 | -2.33942 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -2.29875 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.23499 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -2.1892 |
| ARL8B | ADP-ribosylation factor-like 8B | -2.13523 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -2.12359 |
| ABI1 | abl-interactor 1 | -2.09041 |
| ZNF646 | zinc finger protein 646 | -2.06142 |
| STXBP2 | syntaxin binding protein 2 | -2.02961 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -2.00252 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | -2.00226 |