CRCGN016_MCF10A.WT.HP_24H:D03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-hydroxyphenazine 11.11 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

55 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STIMATE STIM activating enhancer 4.74692
SESN1 sestrin 1 4.0182
BMP4 bone morphogenetic protein 4 3.35362
AGR2 anterior gradient 2 3.33742
MSRA methionine sulfoxide reductase A 3.23447
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 3.2242
ALG8 ALG8, alpha-1,3-glucosyltransferase 3.03576
OLFML2B olfactomedin-like 2B 2.92089
ZNF589 zinc finger protein 589 2.84069
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 2.77018
UVRAG UV radiation resistance associated 2.67302
RSF1 remodeling and spacing factor 1 2.4905
AAMDC adipogenesis associated, Mth938 domain containing 2.41777
THAP12 THAP domain containing 12 2.40617
CGRRF1 cell growth regulator with ring finger domain 1 2.31728
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.31626
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 2.16925
MRPL48 mitochondrial ribosomal protein L48 2.15936
TGDS TDP-glucose 4,6-dehydratase 2.14092
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.10051
GAB2 GRB2-associated binding protein 2 2.09764
MRPL18 mitochondrial ribosomal protein L18 2.04995
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 2.04129
HLA-DMB major histocompatibility complex, class II, DM beta 2.00873

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -5.44823
DNM1L dynamin 1-like -4.98739
RNF167 ring finger protein 167 -4.85888
NGRN neugrin, neurite outgrowth associated -4.65579
HAT1 histone acetyltransferase 1 -4.53084
PCCB propionyl CoA carboxylase, beta polypeptide -4.34874
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.16487
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -4.10057
YME1L1 YME1-like 1 ATPase -4.08015
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.65168
CD320 CD320 molecule -3.57005
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.87684
NT5M 5',3'-nucleotidase, mitochondrial -2.59675
INTS14 integrator complex subunit 14 -2.53456
MDFI MyoD family inhibitor -2.47549
ACAA1 acetyl-CoA acyltransferase 1 -2.47519
SLC39A1 solute carrier family 39 (zinc transporter), member 1 -2.46616
CLSTN3 calsyntenin 3 -2.40736
BASP1 brain abundant, membrane attached signal protein 1 -2.39085
NISCH nischarin -2.36747
BORCS8 BLOC-1 related complex subunit 8 -2.33942
ARID4B AT rich interactive domain 4B (RBP1-like) -2.29875
KDM3A lysine (K)-specific demethylase 3A -2.23499
CDH15 cadherin 15, type 1, M-cadherin (myotubule) -2.1892
ARL8B ADP-ribosylation factor-like 8B -2.13523
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy -2.12359
ABI1 abl-interactor 1 -2.09041
ZNF646 zinc finger protein 646 -2.06142
STXBP2 syntaxin binding protein 2 -2.02961
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -2.00252
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -2.00226