CRCGN016_MCF10A.WT.HP_24H:D06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nTZDpa 5.56 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

44 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 5.48745
PPOX protoporphyrinogen oxidase 5.08968
SIRT3 sirtuin 3 3.54324
AGR2 anterior gradient 2 3.49878
RIC8A RIC8 guanine nucleotide exchange factor A 2.9712
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.75947
HBA1 hemoglobin, alpha 1 2.70862
DEAF1 DEAF1 transcription factor 2.64069
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.57979
LOC124907090 ankyrin repeat domain-containing protein SOWAHC-like 2.54011
SNAP25 synaptosomal-associated protein, 25kDa 2.49928
GDI2 GDP dissociation inhibitor 2 2.41601
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 2.27341
TMEM135 transmembrane protein 135 2.25523
FKBP14 FK506 binding protein 14, 22 kDa 2.18005
RAB21 RAB21, member RAS oncogene family 2.13425
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.13199
NUP107 nucleoporin 107kDa 2.11708
HBB hemoglobin, beta 2.08612
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 2.07961
MYLK myosin light chain kinase 2.07334
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.06373
TMEM41B transmembrane protein 41B 2.04502

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -5.14272
S100A8 S100 calcium binding protein A8 -4.92262
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.65274
MTERF3 mitochondrial transcription termination factor 3 -3.52362
HAT1 histone acetyltransferase 1 -2.96785
RNF111 ring finger protein 111 -2.85053
BASP1 brain abundant, membrane attached signal protein 1 -2.5898
MRPS2 mitochondrial ribosomal protein S2 -2.55228
TES testin LIM domain protein -2.49789
TBCB tubulin folding cofactor B -2.49103
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.40084
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 -2.39254
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.22314
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -2.18375
KIF14 kinesin family member 14 -2.13345
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 -2.07781
PYY peptide YY -2.07658
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 -2.05664
S100A9 S100 calcium binding protein A9 -2.04123
ACOT8 acyl-CoA thioesterase 8 -2.01778
PRR5L proline rich 5 like -2.01241