| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tributyltin 0.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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67 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 3.9365 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 3.8396 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 3.46024 |
| FHL2 | four and a half LIM domains 2 | 3.44062 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 3.21521 |
| KLHL21 | kelch-like family member 21 | 3.12438 |
| IL1B | interleukin 1, beta | 3.09586 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.74157 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 2.67494 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.56878 |
| AGR2 | anterior gradient 2 | 2.52624 |
| E2F2 | E2F transcription factor 2 | 2.49879 |
| IL4R | interleukin 4 receptor | 2.48778 |
| HBA1 | hemoglobin, alpha 1 | 2.45997 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 2.41108 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.39818 |
| SMAD3 | SMAD family member 3 | 2.38579 |
| AXIN1 | axin 1 | 2.36394 |
| CTSL | cathepsin L | 2.29835 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 2.23544 |
| HMGA2 | high mobility group AT-hook 2 | 2.22088 |
| SPRR3 | small proline-rich protein 3 | 2.18049 |
| CTPS1 | CTP synthase 1 | 2.172 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 2.09987 |
| UCK2 | uridine-cytidine kinase 2 | 2.04925 |
| PGM1 | phosphoglucomutase 1 | 2.04617 |
| PRKCQ | protein kinase C, theta | 2.03525 |
| ITGAV | integrin, alpha V | 2.02646 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 2.01895 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 2.00407 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FAIM | Fas apoptotic inhibitory molecule | -4.59238 |
| PMM2 | phosphomannomutase 2 | -3.49996 |
| RBM15B | RNA binding motif protein 15B | -3.35218 |
| CEP70 | centrosomal protein 70kDa | -2.92419 |
| RGS2 | regulator of G-protein signaling 2 | -2.88051 |
| S100A4 | S100 calcium binding protein A4 | -2.85917 |
| HMG20B | high mobility group 20B | -2.85334 |
| RPA3 | replication protein A3, 14kDa | -2.70403 |
| NFIL3 | nuclear factor, interleukin 3 regulated | -2.56349 |
| RXYLT1 | ribitol xylosyltransferase 1 | -2.54454 |
| PRR15L | proline rich 15-like | -2.48893 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.42702 |
| CNGA3 | cyclic nucleotide gated channel alpha 3 | -2.36755 |
| ZNF8 | zinc finger protein 8 | -2.36479 |
| ADI1 | acireductone dioxygenase 1 | -2.30691 |
| ADRB2 | adrenoceptor beta 2, surface | -2.2937 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.28904 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.21954 |
| CORO1A | coronin, actin binding protein, 1A | -2.21439 |
| PARD6A | par-6 family cell polarity regulator alpha | -2.21102 |
| BAD | BCL2-associated agonist of cell death | -2.2015 |
| HOXA5 | homeobox A5 | -2.19884 |
| EXPH5 | exophilin 5 | -2.19428 |
| PIERCE1 | piercer of microtubule wall 1 | -2.18555 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -2.13368 |
| DNAI4 | dynein axonemal intermediate chain 4 | -2.12201 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | -2.11549 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | -2.07912 |
| SSBP2 | single-stranded DNA binding protein 2 | -2.0483 |
| CPM | carboxypeptidase M | -2.0463 |
| ANKRD12 | ankyrin repeat domain 12 | -2.03215 |
| TBC1D15 | TBC1 domain family, member 15 | -2.02811 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -2.02789 |
| TMC5 | transmembrane channel-like 5 | -2.0242 |
| TBC1D30 | TBC1 domain family, member 30 | -2.01704 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -2.00438 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -2.00409 |
