CRCGN016_MCF10A.WT.HP_24H:D10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description rosi with tphp perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

76 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
OLFML2B olfactomedin-like 2B 4.79639
DHRS2 dehydrogenase/reductase (SDR family) member 2 4.76075
GATA2 GATA binding protein 2 4.47541
HBA1 hemoglobin, alpha 1 4.38481
KLHL21 kelch-like family member 21 3.75804
PPOX protoporphyrinogen oxidase 3.61343
ACAA1 acetyl-CoA acyltransferase 1 3.41985
CNPY3 canopy FGF signaling regulator 3 3.19715
BZW2 basic leucine zipper and W2 domains 2 3.03416
GARRE1 granule associated Rac and RHOG effector 1 3.00036
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.93832
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.65748
COMP cartilage oligomeric matrix protein 2.58146
ZW10 zw10 kinetochore protein 2.57624
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 2.55672
TBX2 T-box 2 2.55242
LOXL1 lysyl oxidase-like 1 2.47976
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.47047
LGMN legumain 2.42571
SYNGAP1 synaptic Ras GTPase activating protein 1 2.35775
TM2D3 TM2 domain containing 3 2.29923
UBA7 ubiquitin-like modifier activating enzyme 7 2.13243
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 2.08146
ZBTB11 zinc finger and BTB domain containing 11 2.08141
APOL1 apolipoprotein L, 1 2.05055
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 2.05039
RHOT2 ras homolog family member T2 2.02456
BAMBI BMP and activin membrane-bound inhibitor 2.01494
MAN2B2 mannosidase, alpha, class 2B, member 2 2.00326

decreased expression

Symbol Name Standardized Value
CHMP4B charged multivesicular body protein 4B -5.05848
TSPAN4 tetraspanin 4 -4.45752
MRPS2 mitochondrial ribosomal protein S2 -4.28575
COG2 component of oligomeric golgi complex 2 -4.25162
NRIP1 nuclear receptor interacting protein 1 -4.17101
PPP1R26 protein phosphatase 1, regulatory subunit 26 -4.12031
PAEP progestagen-associated endometrial protein -4.05652
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.93653
MAPK13 mitogen-activated protein kinase 13 -3.81653
FHL2 four and a half LIM domains 2 -3.34404
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.31487
TLK2 tousled-like kinase 2 -3.16209
RGS2 regulator of G-protein signaling 2 -3.16064
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.91697
MZT2A mitotic spindle organizing protein 2A -2.5961
TIMP1 TIMP metallopeptidase inhibitor 1 -2.59035
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -2.56198
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -2.48248
SGK1 serum/glucocorticoid regulated kinase 1 -2.4035
TRAPPC6A trafficking protein particle complex 6A -2.39012
MPST mercaptopyruvate sulfurtransferase -2.38838
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -2.38497
MSMO1 methylsterol monooxygenase 1 -2.38327
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.36916
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 -2.34625
HOXA5 homeobox A5 -2.32322
BPHL biphenyl hydrolase-like (serine hydrolase) -2.31681
ZNF415 zinc finger protein 415 -2.31014
PBLD phenazine biosynthesis-like protein domain containing -2.29859
NRGN neurogranin (protein kinase C substrate, RC3) -2.29603
S100A14 S100 calcium binding protein A14 -2.25534
DCAF10 DDB1 and CUL4 associated factor 10 -2.20308
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.19985
RFC2 replication factor C (activator 1) 2, 40kDa -2.18819
SEC16A SEC16 homolog A (S. cerevisiae) -2.16166
ANXA13 annexin A13 -2.14808
BET1 Bet1 golgi vesicular membrane trafficking protein -2.13603
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -2.12059
BGLAP bone gamma-carboxyglutamate (gla) protein -2.11754
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.10046
CLDN3 claudin 3 -2.07559
TFPI2 tissue factor pathway inhibitor 2 -2.05107
HPCA hippocalcin -2.03581
MYG1 MYG1 exonuclease -2.0314
MZT2B mitotic spindle organizing protein 2B -2.03126
STAT4 signal transducer and activator of transcription 4 -2.00496
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10 -2.00292