CRCGN016_MCF10A.WT.HP_24H:D11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description rosi with tphp perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TSEN2 TSEN2 tRNA splicing endonuclease subunit 3.58916
CCP110 centriolar coiled coil protein 110kDa 3.58275
STK10 serine/threonine kinase 10 3.56175
GARRE1 granule associated Rac and RHOG effector 1 3.40392
TBX2 T-box 2 2.63805
MICALL1 MICAL-like 1 2.41658
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.3642
BACE2 beta-site APP-cleaving enzyme 2 2.05088
AGR2 anterior gradient 2 2.04522
LGMN legumain 2.01094

decreased expression

Symbol Name Standardized Value
ANXA2 annexin A2 -4.06005
TIMP1 TIMP metallopeptidase inhibitor 1 -3.72726
CYCS cytochrome c, somatic -3.38939
NUP85 nucleoporin 85kDa -3.00488
TLK2 tousled-like kinase 2 -2.54983
SLC38A12 solute carrier family 38 member 12 -2.53919
PARP2 poly (ADP-ribose) polymerase 2 -2.49803
SORBS3 sorbin and SH3 domain containing 3 -2.49269
SCAND1 SCAN domain containing 1 -2.4478
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.20882
DUSP8 dual specificity phosphatase 8 -2.05602