CRCGN016_MCF10A.WT.HP_24H:D13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4,5-trichlorophenoxyacetic acid 100.97 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.78484
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 3.72653
AGR2 anterior gradient 2 3.57111
MSRA methionine sulfoxide reductase A 3.10861
BAMBI BMP and activin membrane-bound inhibitor 3.07877
MAP7 microtubule-associated protein 7 2.95297
TIAM1 T-cell lymphoma invasion and metastasis 1 2.67328
MICALL1 MICAL-like 1 2.50619
GALE UDP-galactose-4-epimerase 2.34836
CAPN1 calpain 1, (mu/I) large subunit 2.29867
FZD1 frizzled class receptor 1 2.2224
RBKS ribokinase 2.02613
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.02545
NRBF2 nuclear receptor binding factor 2 2.01891

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -3.62455
TCEA2 transcription elongation factor A (SII), 2 -3.2885
UFM1 ubiquitin-fold modifier 1 -3.10533
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.1007
CCNB1 cyclin B1 -3.05247
GDF15 growth differentiation factor 15 -2.88601
TNIP1 TNFAIP3 interacting protein 1 -2.49783
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.48338
ANXA2 annexin A2 -2.43567
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 -2.3013
BPHL biphenyl hydrolase-like (serine hydrolase) -2.25368
EIF5 eukaryotic translation initiation factor 5 -2.13433
SCAND1 SCAN domain containing 1 -2.11409
NR1I3 nuclear receptor subfamily 1, group I, member 3 -2.07368
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -2.03504