CRCGN016_MCF10A.WT.HP_24H:D16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-ethyl-2-hexenal 99.96 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

22 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GPER1 G protein-coupled estrogen receptor 1 5.00184
UGDH UDP-glucose 6-dehydrogenase 4.79445
PPARG peroxisome proliferator-activated receptor gamma 4.34197
OLFML2B olfactomedin-like 2B 3.97856
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.67331
CNPY3 canopy FGF signaling regulator 3 2.8463
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.52636
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 2.43318
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.3193
COMP cartilage oligomeric matrix protein 2.31696
THAP11 THAP domain containing 11 2.19625
TBX2 T-box 2 2.14464
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.09393
INTS3 integrator complex subunit 3 2.08897
AGR2 anterior gradient 2 2.00006

decreased expression

Symbol Name Standardized Value
VDAC1 voltage-dependent anion channel 1 -4.06322
TLCD3A TLC domain containing 3A -3.46298
S100A8 S100 calcium binding protein A8 -3.42988
CD44 CD44 molecule (Indian blood group) -2.86108
RAI14 retinoic acid induced 14 -2.3677
CSRP1 cysteine and glycine-rich protein 1 -2.12262
HOXA10-HOXA9 HOXA10-HOXA9 readthrough -2.037