CRCGN016_MCF10A.WT.HP_24H:D17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-ethyl-2-hexenal 33.32 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WFS1 Wolfram syndrome 1 (wolframin) 3.8214
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.53137
WIF1 WNT inhibitory factor 1 3.41418
MEF2C myocyte enhancer factor 2C 3.12468
DENND2D DENN/MADD domain containing 2D 2.36296

decreased expression

Symbol Name Standardized Value
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.55089
TIMP1 TIMP metallopeptidase inhibitor 1 -3.33795
TENT4A terminal nucleotidyltransferase 4A -3.13939
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.81899
GTPBP8 GTP-binding protein 8 (putative) -2.52271
MT1X metallothionein 1X -2.47188
OXA1L oxidase (cytochrome c) assembly 1-like -2.09692
LDHD lactate dehydrogenase D -2.01369
TENT2 terminal nucleotidyltransferase 2 -2.00663