CRCGN016_MCF10A.WT.HP_24H:D18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-ethyl-2-hexenal 11.11 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.79114
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.32924
CERK ceramide kinase 3.9085
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.67619
WASF3 WAS protein family, member 3 3.18451
PRR15L proline rich 15-like 3.07576
RPP38 ribonuclease P/MRP 38kDa subunit 2.88195
PHKG2 phosphorylase kinase, gamma 2 (testis) 2.49809
NOD1 nucleotide-binding oligomerization domain containing 1 2.33721
TXNL4B thioredoxin-like 4B 2.20779
ZFP36 ZFP36 ring finger protein 2.15497
ACE2 angiotensin I converting enzyme 2 2.15163
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 2.14005
LRRC19 leucine rich repeat containing 19 2.10733
ASPA aspartoacylase 2.10484
PRR14 proline rich 14 2.02042
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 2.0116

decreased expression

Symbol Name Standardized Value
UFM1 ubiquitin-fold modifier 1 -4.57307
HSPA8 heat shock 70kDa protein 8 -4.2781
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.24151
NUSAP1 nucleolar and spindle associated protein 1 -2.79341
BASP1 brain abundant, membrane attached signal protein 1 -2.7441
TWF2 twinfilin actin binding protein 2 -2.40151
WSB2 WD repeat and SOCS box containing 2 -2.40088
CRTAP cartilage associated protein -2.37993
MSMO1 methylsterol monooxygenase 1 -2.28377
KRT14 keratin 14, type I -2.28257
DUSP4 dual specificity phosphatase 4 -2.26392
PRUNE1 prune exopolyphosphatase 1 -2.11178
TOMM34 translocase of outer mitochondrial membrane 34 -2.08182
ATP5F1E ATP synthase F1 subunit epsilon -2.02144