CRCGN016_MCF10A.WT.HP_24H:D22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description picloram, technical grade 102.29 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HBA1 hemoglobin, alpha 1 4.4204
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 3.82023
HACD3 3-hydroxyacyl-CoA dehydratase 3 3.76778
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 3.72227
HBB hemoglobin, beta 3.67495
PDIA5 protein disulfide isomerase family A, member 5 3.51298
ACAA1 acetyl-CoA acyltransferase 1 3.12705
KDM5D lysine (K)-specific demethylase 5D 2.79995
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.58074
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 2.47553
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.4744
BAD BCL2-associated agonist of cell death 2.43494
GET1 guided entry of tail-anchored proteins factor 1 2.41693
CGRRF1 cell growth regulator with ring finger domain 1 2.19658
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.17517
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 2.03626

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -5.84173
KIF20A kinesin family member 20A -4.9331
HMG20B high mobility group 20B -4.85796
CD44 CD44 molecule (Indian blood group) -4.26423
LYPLA1 lysophospholipase I -4.20367
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -3.43489
SMC1A structural maintenance of chromosomes 1A -2.69872
MFSD12 major facilitator superfamily domain containing 12 -2.64749
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -2.3694
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -2.27473
MRPL15 mitochondrial ribosomal protein L15 -2.24057
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.2116
PNPLA4 patatin-like phospholipase domain containing 4 -2.15225
PUDP pseudouridine 5'-phosphatase -2.14162
TOMM34 translocase of outer mitochondrial membrane 34 -2.12099
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.04632
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -2.04021