CRCGN016_MCF10A.WT.HP_24H:D22 Gene Set
Genes
33 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HBA1
|
hemoglobin, alpha 1
|
4.4204
|
|
PLP2
|
proteolipid protein 2 (colonic epithelium-enriched)
|
3.82023
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
3.76778
|
|
DFFA
|
DNA fragmentation factor, 45kDa, alpha polypeptide
|
3.72227
|
|
HBB
|
hemoglobin, beta
|
3.67495
|
|
PDIA5
|
protein disulfide isomerase family A, member 5
|
3.51298
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
3.12705
|
|
KDM5D
|
lysine (K)-specific demethylase 5D
|
2.79995
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
2.58074
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.47553
|
|
EIF1AY
|
eukaryotic translation initiation factor 1A, Y-linked
|
2.4744
|
|
BAD
|
BCL2-associated agonist of cell death
|
2.43494
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
2.41693
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
2.19658
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
2.17517
|
|
PSME1
|
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
|
2.03626
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GDF15
|
growth differentiation factor 15
|
-5.84173
|
|
KIF20A
|
kinesin family member 20A
|
-4.9331
|
|
HMG20B
|
high mobility group 20B
|
-4.85796
|
|
CD44
|
CD44 molecule (Indian blood group)
|
-4.26423
|
|
LYPLA1
|
lysophospholipase I
|
-4.20367
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-3.43489
|
|
SMC1A
|
structural maintenance of chromosomes 1A
|
-2.69872
|
|
MFSD12
|
major facilitator superfamily domain containing 12
|
-2.64749
|
|
ATP6V1H
|
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
|
-2.3694
|
|
ZRSR2
|
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
|
-2.27473
|
|
MRPL15
|
mitochondrial ribosomal protein L15
|
-2.24057
|
|
LYPLA1-TCEA1
|
LYPLA1-TCEA1 readthrough
|
-2.2116
|
|
PNPLA4
|
patatin-like phospholipase domain containing 4
|
-2.15225
|
|
PUDP
|
pseudouridine 5'-phosphatase
|
-2.14162
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
-2.12099
|
|
MAPKAPK3
|
mitogen-activated protein kinase-activated protein kinase 3
|
-2.04632
|
|
LOC124905557
|
eukaryotic translation initiation factor 1A, X-chromosomal
|
-2.04021
|