CRCGN016_MCF10A.WT.HP_24H:D23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description picloram, technical grade 34.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KIF5C kinesin family member 5C 4.67904
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.41337
DHRS2 dehydrogenase/reductase (SDR family) member 2 3.3236
RPP38 ribonuclease P/MRP 38kDa subunit 3.30183
IGHMBP2 immunoglobulin mu binding protein 2 3.20935
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.69752
PLSCR3 phospholipid scramblase 3 2.68339
SATB1 SATB homeobox 1 2.4645
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.1789
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.01735

decreased expression

Symbol Name Standardized Value
TRAPPC3 trafficking protein particle complex 3 -4.76854
CHMP4B charged multivesicular body protein 4B -4.66131
KIF20A kinesin family member 20A -4.36217
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.31267
MRPS15 mitochondrial ribosomal protein S15 -3.56585
BPHL biphenyl hydrolase-like (serine hydrolase) -3.33643
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -3.22164
NCBP3 nuclear cap binding subunit 3 -2.72859
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.55258
BASP1 brain abundant, membrane attached signal protein 1 -2.47985
ACAA1 acetyl-CoA acyltransferase 1 -2.41177
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.40106
PRSS21 protease, serine, 21 (testisin) -2.3822
KDM3A lysine (K)-specific demethylase 3A -2.33465
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -2.32717
OSBPL10 oxysterol binding protein-like 10 -2.28814
HSPA1A heat shock 70kDa protein 1A -2.18535
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -2.15766
ZMYM4 zinc finger, MYM-type 4 -2.15157
AGO1 argonaute RISC catalytic component 1 -2.12825
RFXANK regulatory factor X-associated ankyrin-containing protein -2.08959
ADM adrenomedullin -2.07166
IFT20 intraflagellar transport 20 -2.02142
C1QBP complement component 1, q subcomponent binding protein -2.01857