CRCGN016_MCF10A.WT.HP_24H:D24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description picloram, technical grade 11.37 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:D24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.28127
E2F2 E2F transcription factor 2 3.58272
GET1 guided entry of tail-anchored proteins factor 1 2.7483
ADRB2 adrenoceptor beta 2, surface 2.55123
PRR15L proline rich 15-like 2.1539
LYN LYN proto-oncogene, Src family tyrosine kinase 2.13265
CCDC85B coiled-coil domain containing 85B 2.07002
KAT6B K(lysine) acetyltransferase 6B 2.04447

decreased expression

Symbol Name Standardized Value
CHMP4B charged multivesicular body protein 4B -4.13688
CCNB1 cyclin B1 -3.5268
PCCB propionyl CoA carboxylase, beta polypeptide -3.50129
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.39509
PARP2 poly (ADP-ribose) polymerase 2 -3.18238
BPHL biphenyl hydrolase-like (serine hydrolase) -3.0495
ANKRD10 ankyrin repeat domain 10 -2.8387
KRT14 keratin 14, type I -2.64602
KDM3A lysine (K)-specific demethylase 3A -2.49776
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.26428
REXO2 RNA exonuclease 2 -2.2263
RPA3 replication protein A3, 14kDa -2.22481
SMC1A structural maintenance of chromosomes 1A -2.05815
HMG20B high mobility group 20B -2.04428
S100A8 S100 calcium binding protein A8 -2.03943