CRCGN016_MCF10A.WT.HP_24H:E01 Gene Set
Genes
54 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:E01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
3.462
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
3.33013
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
3.27732
|
|
TRIB3
|
tribbles pseudokinase 3
|
3.10839
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
3.03919
|
|
MSRA
|
methionine sulfoxide reductase A
|
2.93954
|
|
RTN2
|
reticulon 2
|
2.88508
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
2.82974
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
2.72534
|
|
WDR7
|
WD repeat domain 7
|
2.65223
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
2.55161
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
2.52818
|
|
GLRX
|
glutaredoxin (thioltransferase)
|
2.51112
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
2.45629
|
|
SHISAL1
|
shisa like 1
|
2.33464
|
|
CERK
|
ceramide kinase
|
2.26135
|
|
S100A4
|
S100 calcium binding protein A4
|
2.22517
|
|
PPOX
|
protoporphyrinogen oxidase
|
2.22159
|
|
INSIG1
|
insulin induced gene 1
|
2.22141
|
|
PMM2
|
phosphomannomutase 2
|
2.20999
|
|
GREM1
|
gremlin 1, DAN family BMP antagonist
|
2.17277
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.16318
|
|
MINPP1
|
multiple inositol-polyphosphate phosphatase 1
|
2.16184
|
|
ACVRL1
|
activin A receptor type II-like 1
|
2.14697
|
|
IL1B
|
interleukin 1, beta
|
2.12956
|
|
RAP1GAP
|
RAP1 GTPase activating protein
|
2.09496
|
|
NIT1
|
nitrilase 1
|
2.04546
|
|
RTN1
|
reticulon 1
|
2.02865
|
|
ADGRL4
|
adhesion G protein-coupled receptor L4
|
2.00295
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.39912
|
|
HOXA5
|
homeobox A5
|
-3.69038
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
-3.13441
|
|
LDHD
|
lactate dehydrogenase D
|
-2.9189
|
|
STMN1
|
stathmin 1
|
-2.88394
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
-2.60321
|
|
TRAP1
|
TNF receptor-associated protein 1
|
-2.58951
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.31217
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
-2.29247
|
|
TP53
|
tumor protein p53
|
-2.28666
|
|
PLK1
|
polo-like kinase 1
|
-2.25505
|
|
ZNF443
|
zinc finger protein 443
|
-2.24011
|
|
OXCT1
|
3-oxoacid CoA transferase 1
|
-2.2344
|
|
ATP1B1
|
ATPase, Na+/K+ transporting, beta 1 polypeptide
|
-2.22379
|
|
CD81
|
CD81 molecule
|
-2.20853
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.20144
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
-2.17652
|
|
CDC20
|
cell division cycle 20
|
-2.12611
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.12454
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-2.09886
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-2.09613
|
|
TOMM70
|
translocase of outer mitochondrial membrane 70
|
-2.09549
|
|
IRX5
|
iroquois homeobox 5
|
-2.09133
|
|
JPT2
|
Jupiter microtubule associated homolog 2
|
-2.026
|
|
ENOPH1
|
enolase-phosphatase 1
|
-2.02195
|