CRCGN016_MCF10A.WT.HP_24H:E03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description indole 11.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:E03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 3.09958
STIMATE STIM activating enhancer 3.02447
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.70024
EDN1 endothelin 1 2.43612
MAMLD1 mastermind-like domain containing 1 2.27923
TPD52L2 tumor protein D52-like 2 2.17823
PPARG peroxisome proliferator-activated receptor gamma 2.05662
CCNA1 cyclin A1 2.01601

decreased expression

Symbol Name Standardized Value
SCYL3 SCY1-like 3 (S. cerevisiae) -5.20633
MTERF3 mitochondrial transcription termination factor 3 -3.82578
ARID4B AT rich interactive domain 4B (RBP1-like) -3.5888
RPA3 replication protein A3, 14kDa -2.67638
CREG1 cellular repressor of E1A-stimulated genes 1 -2.66504
EXOSC4 exosome component 4 -2.66311
ADI1 acireductone dioxygenase 1 -2.51473
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.44557