CRCGN016_MCF10A.WT.HP_24H:E06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diphenyl-p-phenylenediamine 11.16 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:E06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 3.03179
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.02867
TLR4 toll-like receptor 4 3.01775
PDIA5 protein disulfide isomerase family A, member 5 3.00692
MAP7 microtubule-associated protein 7 2.98248
TBPL1 TBP-like 1 2.59939
CCL2 chemokine (C-C motif) ligand 2 2.59157
HBB hemoglobin, beta 2.5107
KLHL9 kelch-like family member 9 2.33946
NUTF2 nuclear transport factor 2 2.27101
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 2.26075
TXNL4B thioredoxin-like 4B 2.2327
STAP2 signal transducing adaptor family member 2 2.21447
SYNE2 spectrin repeat containing, nuclear envelope 2 2.19271

decreased expression

Symbol Name Standardized Value
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.4346
KIF14 kinesin family member 14 -3.23764
PUF60 poly-U binding splicing factor 60KDa -3.15994
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.75356
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 -2.71486
PSRC1 proline/serine-rich coiled-coil 1 -2.09495
CDC20 cell division cycle 20 -2.04551