CRCGN016_MCF10A.WT.HP_24H:E09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 3,3'-dimethylbenzidine.2hcl 11.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:E09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 3.64449
PEX11A peroxisomal biogenesis factor 11 alpha 3.46381
ACAA1 acetyl-CoA acyltransferase 1 2.87488
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.74541
DENND2D DENN/MADD domain containing 2D 2.37319

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -6.81223
NPDC1 neural proliferation, differentiation and control, 1 -4.71836
PUF60 poly-U binding splicing factor 60KDa -4.64144
SCYL3 SCY1-like 3 (S. cerevisiae) -4.18544
HMG20B high mobility group 20B -4.16522
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.1275
ZDHHC6 zinc finger, DHHC-type containing 6 -4.06932
DSG2 desmoglein 2 -3.9669
CANT1 calcium activated nucleotidase 1 -3.25945
CAB39 calcium binding protein 39 -3.07471
TM9SF3 transmembrane 9 superfamily member 3 -2.26598
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.21132
BASP1 brain abundant, membrane attached signal protein 1 -2.19839
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.15583
STXBP2 syntaxin binding protein 2 -2.13996
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.13238
RAB1B RAB1B, member RAS oncogene family -2.09111