CRCGN016_MCF10A.WT.HP_24H:E16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinyl acetate 104.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:E16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FZD7 frizzled class receptor 7 4.50134
ADGRE5 adhesion G protein-coupled receptor E5 4.18813
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.12891
DHDDS dehydrodolichyl diphosphate synthase 2.99873
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.87107
AGR2 anterior gradient 2 2.70634
USP6NL USP6 N-terminal like 2.4313
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 2.35166
TLR4 toll-like receptor 4 2.22227
REG1B regenerating islet-derived 1 beta 2.12076
SULT4A1 sulfotransferase family 4A, member 1 2.00388

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.78819
TRIB3 tribbles pseudokinase 3 -3.79449
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.56535
TLCD3A TLC domain containing 3A -3.17737
MSMO1 methylsterol monooxygenase 1 -3.06396
CANT1 calcium activated nucleotidase 1 -3.04081
ACAA1 acetyl-CoA acyltransferase 1 -2.70172
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.50342
TIMP1 TIMP metallopeptidase inhibitor 1 -2.15209
HAX1 HCLS1 associated protein X-1 -2.11111
S100A8 S100 calcium binding protein A8 -2.08436
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 -2.02155