CRCGN016_MCF10A.WT.HP_24H:E18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vinyl acetate 11.56 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

56 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:E18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 5.03308
LOC122526780 uncharacterized LOC122526780 3.28326
MAMLD1 mastermind-like domain containing 1 3.19775
NSG2 neuronal vesicle trafficking associated 2 3.19393
RAB21 RAB21, member RAS oncogene family 3.17266
ADAM10 ADAM metallopeptidase domain 10 3.0684
STMN2 stathmin 2 3.06742
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.74061
IL1B interleukin 1, beta 2.69306
CANT1 calcium activated nucleotidase 1 2.68023
HBB hemoglobin, beta 2.61167
SNX11 sorting nexin 11 2.59302
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 2.55444
SNAP91 synaptosomal-associated protein, 91kDa 2.3921
INA internexin neuronal intermediate filament protein, alpha 2.3734
ATP11B ATPase, class VI, type 11B 2.33266
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.32353
CHGB chromogranin B 2.30678
ACTL6B actin-like 6B 2.30572
MMP1 matrix metallopeptidase 1 2.27923
RUNDC3A RUN domain containing 3A 2.26563
AP3B2 adaptor-related protein complex 3, beta 2 subunit 2.26373
NEFM neurofilament, medium polypeptide 2.23295
PDYN prodynorphin 2.2174
TCEA2 transcription elongation factor A (SII), 2 2.20508
RGS7 regulator of G-protein signaling 7 2.20088
BEX2 brain expressed X-linked 2 2.17632
ASPHD1 aspartate beta-hydroxylase domain containing 1 2.09971
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa 2.07111
GNG4 guanine nucleotide binding protein (G protein), gamma 4 2.06437
VSNL1 visinin-like 1 2.04758
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.01908
OSGEP O-sialoglycoprotein endopeptidase 2.00621

decreased expression

Symbol Name Standardized Value
RNF167 ring finger protein 167 -5.18826
HMG20B high mobility group 20B -4.93965
PSRC1 proline/serine-rich coiled-coil 1 -4.36923
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.91448
PFN1 profilin 1 -3.87934
MSMO1 methylsterol monooxygenase 1 -3.17581
GDF15 growth differentiation factor 15 -3.1521
DERA deoxyribose-phosphate aldolase (putative) -3.12672
MAPK13 mitogen-activated protein kinase 13 -3.11758
STXBP2 syntaxin binding protein 2 -2.93929
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.7312
PMM2 phosphomannomutase 2 -2.70114
MSN moesin -2.61389
ACAA1 acetyl-CoA acyltransferase 1 -2.60429
KDM5C lysine (K)-specific demethylase 5C -2.33913
MATK megakaryocyte-associated tyrosine kinase -2.20657
BMAL2 basic helix-loop-helix ARNT like 2 -2.17742
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 -2.16767
GSTT1 glutathione S-transferase theta 1 -2.14962
TGFBI transforming growth factor, beta-induced, 68kDa -2.14494
ACP5 acid phosphatase 5, tartrate resistant -2.03808
RHCG Rh family, C glycoprotein -2.03431
THAP11 THAP domain containing 11 -2.00996