CRCGN016_MCF10A.WT.HP_24H:E21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description clotrimazole 10.98 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

563 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:E21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 7.9308
AARS1 alanyl-tRNA synthetase 1 6.24865
TRIB3 tribbles pseudokinase 3 6.2268
PSAT1 phosphoserine aminotransferase 1 5.94155
AGR2 anterior gradient 2 5.8934
EVL Enah/Vasp-like 5.81095
GLRX glutaredoxin (thioltransferase) 5.8038
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 5.72335
PHGDH phosphoglycerate dehydrogenase 5.71478
ALAS1 5'-aminolevulinate synthase 1 5.5277
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 5.2608
SNAP25 synaptosomal-associated protein, 25kDa 5.25023
TXNRD1 thioredoxin reductase 1 5.24045
CTSL cathepsin L 5.1666
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.1121
YARS1 tyrosyl-tRNA synthetase 1 4.96605
TLR4 toll-like receptor 4 4.9017
XPOT exportin, tRNA 4.76285
E2F2 E2F transcription factor 2 4.66275
GATA2 GATA binding protein 2 4.64558
GARS1 glycyl-tRNA synthetase 1 4.63275
CARS1 cysteinyl-tRNA synthetase 1 4.63205
LAGE3 L antigen family, member 3 4.5549
LRP10 low density lipoprotein receptor-related protein 10 4.48725
BAMBI BMP and activin membrane-bound inhibitor 4.48135
MSRA methionine sulfoxide reductase A 4.34155
LOC102724560 cystathionine beta-synthase 4.269
VAV3 vav 3 guanine nucleotide exchange factor 4.10418
GFPT1 glutamine--fructose-6-phosphate transaminase 1 4.058
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 4.024
ASNS asparagine synthetase (glutamine-hydrolyzing) 3.9982
SARS1 seryl-tRNA synthetase 1 3.9054
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.7189
PYCR1 pyrroline-5-carboxylate reductase 1 3.68495
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 3.65968
PCSK1 proprotein convertase subtilisin/kexin type 1 3.6313
SQSTM1 sequestosome 1 3.62912
ATF4 activating transcription factor 4 3.6049
WARS1 tryptophanyl-tRNA synthetase 1 3.6003
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 3.5859
SLC35G2 solute carrier family 35, member G2 3.56365
LGMN legumain 3.52955
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 3.51655
SCG3 secretogranin III 3.4803
LOC128125814 uncharacterized LOC128125814 3.43015
TARS1 threonyl-tRNA synthetase 1 3.4042
FOS FBJ murine osteosarcoma viral oncogene homolog 3.38725
SV2B synaptic vesicle glycoprotein 2B 3.38265
EGR1 early growth response 1 3.3776
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.371
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 3.3279
FAM50A family with sequence similarity 50, member A 3.2561
MARS1 methionyl-tRNA synthetase 1 3.2346
SNAP91 synaptosomal-associated protein, 91kDa 3.19865
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 3.13238
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.1282
HMOX1 heme oxygenase 1 3.11895
SYNE3 spectrin repeat containing, nuclear envelope family member 3 3.11275
RUNDC3A RUN domain containing 3A 3.07317
NSG2 neuronal vesicle trafficking associated 2 3.04695
SYT1 synaptotagmin I 3.02007
NEFL neurofilament, light polypeptide 3.01092
SSUH2 ssu-2 homolog (C. elegans) 3.0106
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.0088
TSKU tsukushi, small leucine rich proteoglycan 2.9841
STRA6 stimulated by retinoic acid 6 2.97045
VSIG2 V-set and immunoglobulin domain containing 2 2.97015
ASS1 argininosuccinate synthase 1 2.9363
F7 coagulation factor VII (serum prothrombin conversion accelerator) 2.93115
SMAP1 small ArfGAP 1 2.92465
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.92287
SLC67A1 solute carrier family 67 member 1 2.9216
ODAM odontogenic, ameloblast asssociated 2.92005
CHGB chromogranin B 2.90795
VSNL1 visinin-like 1 2.9011
GRB10 growth factor receptor-bound protein 10 2.88643
NIPSNAP1 nipsnap homolog 1 (C. elegans) 2.87873
CEP57 centrosomal protein 57kDa 2.87025
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.8643
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 2.83885
NARS1 asparaginyl-tRNA synthetase 1 2.83735
ARID3B AT rich interactive domain 3B (BRIGHT-like) 2.83475
NUCB2 nucleobindin 2 2.8282
ARID3A AT rich interactive domain 3A (BRIGHT-like) 2.7815
IARS1 isoleucyl-tRNA synthetase 1 2.7651
NEFM neurofilament, medium polypeptide 2.761
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 2.75995
CNTN1 contactin 1 2.73625
OLFM1 olfactomedin 1 2.72145
NRDC nardilysin convertase 2.72115
ECH1 enoyl CoA hydratase 1, peroxisomal 2.71075
MTFR1 mitochondrial fission regulator 1 2.70652
INHBE inhibin, beta E 2.69725
FAM110A family with sequence similarity 110, member A 2.69415
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 2.68935
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 2.68835
NCK2 NCK adaptor protein 2 2.68735
EGR3 early growth response 3 2.6726
NQO1 NAD(P)H dehydrogenase, quinone 1 2.67123
WWOX WW domain containing oxidoreductase 2.66623
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.6594
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.65655
PRODH2 proline dehydrogenase (oxidase) 2 2.65385
FYN FYN proto-oncogene, Src family tyrosine kinase 2.64225
CDC25B cell division cycle 25B 2.63855
GTPBP2 GTP binding protein 2 2.62785
BEST1 bestrophin 1 2.623
NPY5R neuropeptide Y receptor Y5 2.62205
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 2.61387
OPLAH 5-oxoprolinase (ATP-hydrolysing) 2.61355
VAT1 vesicle amine transport 1 2.6127
TAL1 T-cell acute lymphocytic leukemia 1 2.6012
MBNL2 muscleblind-like splicing regulator 2 2.59602
HLTF helicase-like transcription factor 2.59435
SPX spexin hormone 2.5646
PRH1 proline-rich protein HaeIII subfamily 1 2.5634
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.55875
RBP3 retinol binding protein 3, interstitial 2.5581
HAX1 HCLS1 associated protein X-1 2.55515
PRB2 proline-rich protein BstNI subfamily 2 2.55268
KIF21B kinesin family member 21B 2.53785
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 2.5238
CCDC92 coiled-coil domain containing 92 2.5224
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.5066
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 2.49985
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.49965
RBBP7 retinoblastoma binding protein 7 2.4973
VCY1B variable charge, Y-linked 1B 2.4903
NTS neurotensin 2.4803
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.48015
GSE1 Gse1 coiled-coil protein 2.46858
MUC7 mucin 7, secreted 2.45945
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.45645
MEF2A myocyte enhancer factor 2A 2.45642
KCMF1 potassium channel modulatory factor 1 2.4472
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.4468
LOXL1 lysyl oxidase-like 1 2.4461
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.4352
SIRPG signal-regulatory protein gamma 2.43435
S100PBP S100P binding protein 2.4247
MRAS muscle RAS oncogene homolog 2.41915
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.4128
IGFBP1 insulin-like growth factor binding protein 1 2.41105
NLRP4 NLR family, pyrin domain containing 4 2.411
CES1 carboxylesterase 1 2.4105
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 2.40205
CD248 CD248 molecule, endosialin 2.3914
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.38225
YES1 YES proto-oncogene 1, Src family tyrosine kinase 2.38015
FGF14 fibroblast growth factor 14 2.37705
GNG4 guanine nucleotide binding protein (G protein), gamma 4 2.37615
TMEM53 transmembrane protein 53 2.3681
NIPAL2 NIPA-like domain containing 2 2.35845
FAXDC2 fatty acid hydroxylase domain containing 2 2.35413
P3H1 prolyl 3-hydroxylase 1 2.3434
PELI2 pellino E3 ubiquitin protein ligase family member 2 2.3431
ESYT1 extended synaptotagmin-like protein 1 2.33835
ACTL6B actin-like 6B 2.33812
PCCB propionyl CoA carboxylase, beta polypeptide 2.32925
FMNL1 formin-like 1 2.3255
GCLM glutamate-cysteine ligase, modifier subunit 2.324
ANO10 anoctamin 10 2.3108
TSPO2 translocator protein 2 2.30705
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 2.29165
HBQ1 hemoglobin, theta 1 2.28875
EFR3A EFR3 homolog A (S. cerevisiae) 2.28783
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 2.2833
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 2.28285
PDE3B phosphodiesterase 3B, cGMP-inhibited 2.2801
BEX2 brain expressed X-linked 2 2.27625
EPRS1 glutamyl-prolyl-tRNA synthetase 1 2.27462
NCOA3 nuclear receptor coactivator 3 2.27393
DAO D-amino-acid oxidase 2.27235
BCAS3 breast carcinoma amplified sequence 3 2.2684
STXBP5L syntaxin binding protein 5-like 2.2679
LRRC8D leucine rich repeat containing 8 family, member D 2.2628
ACSL6 acyl-CoA synthetase long-chain family member 6 2.2605
INA internexin neuronal intermediate filament protein, alpha 2.25705
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 2.25087
NPC1L1 NPC1-like 1 2.2457
LOC124908558 X antigen family member 1-like 2.2384
GABARAPL1 GABA(A) receptor-associated protein like 1 2.23443
PAPPA pregnancy-associated plasma protein A, pappalysin 1 2.23362
SIL1 SIL1 nucleotide exchange factor 2.23045
ACBD4 acyl-CoA binding domain containing 4 2.22995
REPS2 RALBP1 associated Eps domain containing 2 2.228
ENAH enabled homolog (Drosophila) 2.2266
KDM7A lysine (K)-specific demethylase 7A 2.22385
IQSEC2 IQ motif and Sec7 domain 2 2.22295
L1CAM L1 cell adhesion molecule 2.22073
SHBG sex hormone-binding globulin 2.22045
MYH10 myosin, heavy chain 10, non-muscle 2.21955
TSPYL2 TSPY-like 2 2.21855
PGAP6 post-GPI attachment to proteins 6 2.21605
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.21385
UGDH UDP-glucose 6-dehydrogenase 2.21255
GDAP1 ganglioside induced differentiation associated protein 1 2.2125
RPH3A rabphilin 3A 2.2028
RMC1 regulator of MON1-CCZ1 2.20095
PCDHB16 protocadherin beta 16 2.19575
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.1898
ZNF711 zinc finger protein 711 2.1895
PRAF2 PRA1 domain family, member 2 2.1891
SYNE2 spectrin repeat containing, nuclear envelope 2 2.18225
GHSR growth hormone secretagogue receptor 2.18095
CARTPT CART prepropeptide 2.18045
NPPA natriuretic peptide A 2.1728
EML4 echinoderm microtubule associated protein like 4 2.17245
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.1659
SYN1 synapsin I 2.1627
HOXC8 homeobox C8 2.1605
SEZ6L seizure related 6 homolog (mouse)-like 2.15403
JARID2 jumonji, AT rich interactive domain 2 2.15363
PARP3 poly (ADP-ribose) polymerase family, member 3 2.1514
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 2.1512
KEL Kell blood group, metallo-endopeptidase 2.14785
PLD3 phospholipase D family, member 3 2.1451
TRAF5 TNF receptor-associated factor 5 2.145
MROH7 maestro heat-like repeat family member 7 2.1419
PRNP prion protein 2.14116
HSPB6 heat shock protein, alpha-crystallin-related, B6 2.1383
PENK proenkephalin 2.137
PEDS1 plasmanylethanolamine desaturase 1 2.1368
SNCB synuclein, beta 2.13505
CATSPERZ catsper channel auxiliary subunit zeta 2.13375
RNF10 ring finger protein 10 2.1336
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.12305
RGN regucalcin 2.1163
PEPD peptidase D 2.1136
RIMS3 regulating synaptic membrane exocytosis 3 2.10625
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 2.10203
RET ret proto-oncogene 2.09868
CD3D CD3d molecule, delta (CD3-TCR complex) 2.09665
ADAM20 ADAM metallopeptidase domain 20 2.09515
CHRDL1 chordin-like 1 2.09325
CSAG2 CSAG family, member 2 2.0912
GDF9 growth differentiation factor 9 2.08825
CPNE2 copine II 2.088
UBL4A ubiquitin-like 4A 2.08285
RCOR1 REST corepressor 1 2.08155
PRB3 proline-rich protein BstNI subfamily 3 2.0786
CLIC4 chloride intracellular channel 4 2.07567
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.06975
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 2.06652
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 2.06647
STATH statherin 2.0653
IER2 immediate early response 2 2.06325
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 2.0632
RNF11 ring finger protein 11 2.0618
MTSS1 metastasis suppressor 1 2.06072
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 2.0606
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 2.05988
HDLBP high density lipoprotein binding protein 2.0591
FOXRED2 FAD-dependent oxidoreductase domain containing 2 2.0545
LONP2 lon peptidase 2, peroxisomal 2.05385
GNG11 guanine nucleotide binding protein (G protein), gamma 11 2.04885
KANSL3 KAT8 regulatory NSL complex subunit 3 2.0461
ABHD4 abhydrolase domain containing 4 2.04505
VLDLR very low density lipoprotein receptor 2.04505
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 2.04355
SOAT2 sterol O-acyltransferase 2 2.04175
JAKMIP2 janus kinase and microtubule interacting protein 2 2.041
COL9A3 collagen, type IX, alpha 3 2.03985
RBKS ribokinase 2.03505
FADS2 fatty acid desaturase 2 2.0344
FTCD formimidoyltransferase cyclodeaminase 2.0336
CDPF1 cysteine-rich, DPF motif domain containing 1 2.0318
GALT galactose-1-phosphate uridylyltransferase 2.03
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 2.02555
MKRN1 makorin ring finger protein 1 2.01822
ACLY ATP citrate lyase 2.01657
PRB4 proline-rich protein BstNI subfamily 4 2.01615
GOLGB1 golgin B1 2.01482
ITM2A integral membrane protein 2A 2.00988
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.00785
MAGEA6 melanoma antigen family A6 2.00712
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.00225
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 2.0021

decreased expression

Symbol Name Standardized Value
DCK deoxycytidine kinase -7.0825
RGS2 regulator of G-protein signaling 2 -5.42435
PCNA proliferating cell nuclear antigen -5.1804
ADRB2 adrenoceptor beta 2, surface -5.1162
S100A8 S100 calcium binding protein A8 -5.0017
UFM1 ubiquitin-fold modifier 1 -4.98485
ISOC1 isochorismatase domain containing 1 -4.97135
RFC2 replication factor C (activator 1) 2, 40kDa -4.96545
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.90613
MRPS16 mitochondrial ribosomal protein S16 -4.76185
RNF167 ring finger protein 167 -4.455
HMG20B high mobility group 20B -4.37737
STMN1 stathmin 1 -3.93945
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -3.83917
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -3.71683
FIRRM FIGNL1 interacting regulator of recombination and mitosis -3.6455
CDC45 cell division cycle 45 -3.61465
GMNN geminin, DNA replication inhibitor -3.5986
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -3.5467
PRR15L proline rich 15-like -3.5214
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.48645
MTERF3 mitochondrial transcription termination factor 3 -3.31325
TLK2 tousled-like kinase 2 -3.29837
BIRC5 baculoviral IAP repeat containing 5 -3.26435
CANT1 calcium activated nucleotidase 1 -3.2276
TSPAN6 tetraspanin 6 -3.1157
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -3.09355
TMEM11 transmembrane protein 11 -3.07665
MSMO1 methylsterol monooxygenase 1 -3.07615
RCC1L RCC1 like -3.0697
NUP85 nucleoporin 85kDa -3.04985
BID BH3 interacting domain death agonist -3.04245
PRCC papillary renal cell carcinoma (translocation-associated) -3.0372
ENY2 enhancer of yellow 2 homolog (Drosophila) -3.02145
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -3.0132
AP4M1 adaptor-related protein complex 4, mu 1 subunit -2.99745
HSPE1 heat shock 10kDa protein 1 -2.98785
PFN1 profilin 1 -2.9725
BASP1 brain abundant, membrane attached signal protein 1 -2.9708
HAT1 histone acetyltransferase 1 -2.96665
SCYL3 SCY1-like 3 (S. cerevisiae) -2.9436
TUBB6 tubulin, beta 6 class V -2.9312
CYCS cytochrome c, somatic -2.92245
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -2.89905
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -2.8863
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -2.88445
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.86965
TTI2 TELO2 interacting protein 2 -2.85955
MRPS35 mitochondrial ribosomal protein S35 -2.84547
TRIM21 tripartite motif containing 21 -2.83135
PAK1IP1 PAK1 interacting protein 1 -2.80295
XPO1 exportin 1 -2.7871
HDAC2 histone deacetylase 2 -2.78115
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.78065
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.77675
PYDC1 PYD (pyrin domain) containing 1 -2.77565
MPC2 mitochondrial pyruvate carrier 2 -2.7601
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -2.75567
ACAA1 acetyl-CoA acyltransferase 1 -2.75038
GADD45B growth arrest and DNA-damage-inducible, beta -2.73248
SMG8 SMG8 nonsense mediated mRNA decay factor -2.72635
ZNF83 zinc finger protein 83 -2.716
COIL coilin -2.70603
GTPBP8 GTP-binding protein 8 (putative) -2.70575
GTF2A2 general transcription factor IIA, 2, 12kDa -2.7021
BCL7B B-cell CLL/lymphoma 7B -2.69865
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.69405
HYAL2 hyaluronoglucosaminidase 2 -2.6933
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.69125
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -2.6839
ZC2HC1A zinc finger, C2HC-type containing 1A -2.6789
HOXA5 homeobox A5 -2.67155
RBM14-RBM4 RBM14-RBM4 readthrough -2.6707
ATP5ME ATP synthase membrane subunit e -2.66803
CD81 CD81 molecule -2.66695
NEK4 NIMA-related kinase 4 -2.66475
TMEM50A transmembrane protein 50A -2.663
RPP30 ribonuclease P/MRP 30kDa subunit -2.6629
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.6567
TLR3 toll-like receptor 3 -2.6494
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.64205
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -2.6376
ZNF189 zinc finger protein 189 -2.62225
UBE2C ubiquitin-conjugating enzyme E2C -2.61135
FEN1 flap structure-specific endonuclease 1 -2.60938
METTL2A methyltransferase like 2A -2.60628
MRPS17 mitochondrial ribosomal protein S17 -2.5912
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.57995
CDK1 cyclin-dependent kinase 1 -2.5783
CCNDBP1 cyclin D-type binding-protein 1 -2.57615
FJX1 four jointed box 1 (Drosophila) -2.5685
HEATR3 HEAT repeat containing 3 -2.5646
SRI sorcin -2.5584
PARP1 poly (ADP-ribose) polymerase 1 -2.55355
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -2.54985
POLR1G RNA polymerase I subunit G -2.546
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.54455
DSN1 DSN1, MIS12 kinetochore complex component -2.54435
RBM48 RNA binding motif protein 48 -2.54317
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.53485
ZWINT ZW10 interacting kinetochore protein -2.53155
NOL11 nucleolar protein 11 -2.529
AUNIP aurora kinase A and ninein interacting protein -2.5259
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.4994
LSG1 large 60S subunit nuclear export GTPase 1 -2.497
NME6 NME/NM23 nucleoside diphosphate kinase 6 -2.4916
RBM28 RNA binding motif protein 28 -2.49145
NUP93 nucleoporin 93kDa -2.4908
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.48815
TFAM transcription factor A, mitochondrial -2.48693
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -2.48395
MFAP1 microfibrillar-associated protein 1 -2.483
UPK3B uroplakin 3B -2.4796
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 -2.47633
SNRPF small nuclear ribonucleoprotein polypeptide F -2.46425
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.46155
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.4615
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.4551
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.45335
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -2.44795
HAUS3 HAUS augmin-like complex, subunit 3 -2.4367
EVI2A ecotropic viral integration site 2A -2.43645
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) -2.43405
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.4332
PRPF4 pre-mRNA processing factor 4 -2.4321
CDC20 cell division cycle 20 -2.42885
ZW10 zw10 kinetochore protein -2.42405
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -2.41743
SEC61G Sec61 gamma subunit -2.41655
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) -2.41497
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.41055
GOLT1B golgi transport 1B -2.4021
DPH2 DPH2 homolog (S. cerevisiae) -2.39735
RBBP5 retinoblastoma binding protein 5 -2.39465
ERI2 ERI1 exoribonuclease family member 2 -2.3904
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.38645
MRPS27 mitochondrial ribosomal protein S27 -2.3831
NLRP2B NLR family pyrin domain containing 2B -2.37545
ZNF669 zinc finger protein 669 -2.36065
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit -2.357
TENM4 teneurin transmembrane protein 4 -2.35485
THAP1 THAP domain containing, apoptosis associated protein 1 -2.35335
TEX10 testis expressed 10 -2.3515
PLK1 polo-like kinase 1 -2.34215
SETMAR SET domain and mariner transposase fusion gene -2.33835
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.3379
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -2.33755
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -2.3347
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 -2.33165
RBM42 RNA binding motif protein 42 -2.3296
PYY peptide YY -2.32545
RAD51AP1 RAD51 associated protein 1 -2.32245
SEM1 SEM1 26S proteasome subunit -2.32075
PSRC1 proline/serine-rich coiled-coil 1 -2.30925
CD320 CD320 molecule -2.3075
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.3007
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.2971
PCGF1 polycomb group ring finger 1 -2.29485
FLCN folliculin -2.29425
CDK7 cyclin-dependent kinase 7 -2.29235
LBR lamin B receptor -2.2914
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.28955
CCNB2 cyclin B2 -2.2865
SPARCL1 SPARC-like 1 (hevin) -2.2864
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -2.28315
RPA3 replication protein A3, 14kDa -2.2811
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -2.27935
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.27715
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -2.2749
RIGI RNA sensor RIG-I -2.2661
ZNF26 zinc finger protein 26 -2.2628
GOLGA7 golgin A7 -2.2613
SAP30 Sin3A-associated protein, 30kDa -2.25525
TMPO thymopoietin -2.25337
NOTCH1 notch 1 -2.2532
RFWD3 ring finger and WD repeat domain 3 -2.2516
TEFM transcription elongation factor, mitochondrial -2.25105
ZNF593 zinc finger protein 593 -2.24705
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -2.24625
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.2461
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa -2.24125
ZNF813 zinc finger protein 813 -2.24055
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.2388
PPIF peptidylprolyl isomerase F -2.23502
KIFC1 kinesin family member C1 -2.225
RABIF RAB interacting factor -2.21543
CLDN4 claudin 4 -2.21005
ZNF143 zinc finger protein 143 -2.2054
CDC6 cell division cycle 6 -2.20535
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -2.20385
NOP56 NOP56 ribonucleoprotein -2.20187
ZNF586 zinc finger protein 586 -2.1988
BORA bora, aurora kinase A activator -2.1981
RRAGA Ras-related GTP binding A -2.1963
NCS1 neuronal calcium sensor 1 -2.19445
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.1934
SMNDC1 survival motor neuron domain containing 1 -2.19015
MYNN myoneurin -2.1862
ABHD11 abhydrolase domain containing 11 -2.1854
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 -2.1813
SPATA5L1 spermatogenesis associated 5-like 1 -2.17877
TMCO1 transmembrane and coiled-coil domains 1 -2.17735
PHACTR1 phosphatase and actin regulator 1 -2.1773
EXOSC8 exosome component 8 -2.17205
METTL13 methyltransferase like 13 -2.17175
TOR1AIP2 torsin A interacting protein 2 -2.1682
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -2.1674
HLX H2.0-like homeobox -2.1668
PCDH17 protocadherin 17 -2.1572
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -2.157
MCM5 minichromosome maintenance complex component 5 -2.15237
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -2.15125
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.14995
MRPL19 mitochondrial ribosomal protein L19 -2.1496
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -2.14605
CENPX centromere protein X -2.1427
LMNB1 lamin B1 -2.1425
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.14198
MCM3 minichromosome maintenance complex component 3 -2.1414
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.1392
MED28 mediator complex subunit 28 -2.13465
UBIAD1 UbiA prenyltransferase domain containing 1 -2.13435
TRIM28 tripartite motif containing 28 -2.1306
LRRC15 leucine rich repeat containing 15 -2.1293
TBC1D10B TBC1 domain family, member 10B -2.12655
SLC61A1 solute carrier family 61 member 1 -2.1264
HPS6 Hermansky-Pudlak syndrome 6 -2.1259
MCM7 minichromosome maintenance complex component 7 -2.12523
SIVA1 SIVA1, apoptosis-inducing factor -2.12482
TXNDC9 thioredoxin domain containing 9 -2.12363
KLHL2 kelch-like family member 2 -2.1228
SHPK sedoheptulokinase -2.11985
NECAP2 NECAP endocytosis associated 2 -2.1188
MED21 mediator complex subunit 21 -2.11695
THAP12 THAP domain containing 12 -2.11415
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') -2.113
SRSF2 serine/arginine-rich splicing factor 2 -2.1119
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial -2.10935
SNRPC small nuclear ribonucleoprotein polypeptide C -2.1076
TSPAN15 tetraspanin 15 -2.0994
ZNF692 zinc finger protein 692 -2.0965
SAR1A secretion associated, Ras related GTPase 1A -2.08733
FUS FUS RNA binding protein -2.08245
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -2.0815
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.0804
CISD1 CDGSH iron sulfur domain 1 -2.0792
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -2.07238
TTYH1 tweety family member 1 -2.072
AURKA aurora kinase A -2.07145
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -2.071
KAT6B K(lysine) acetyltransferase 6B -2.06908
ORC6 origin recognition complex, subunit 6 -2.06755
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 -2.06725
EIF4E eukaryotic translation initiation factor 4E -2.06503
YJU2 YJU2 splicing factor homolog -2.06205
SIDT1 SID1 transmembrane family, member 1 -2.0609
HINFP histone H4 transcription factor -2.06015
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -2.05813
TCL1B T-cell leukemia/lymphoma 1B -2.0578
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.0569
MCMBP minichromosome maintenance complex binding protein -2.05465
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) -2.05135
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha -2.0508
CDC23 cell division cycle 23 -2.0505
RFC3 replication factor C (activator 1) 3, 38kDa -2.05018
SAFB2 scaffold attachment factor B2 -2.04903
SRSF7 serine/arginine-rich splicing factor 7 -2.04737
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -2.0431
SRRM1 serine/arginine repetitive matrix 1 -2.04285
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.0353
DSCC1 DNA replication and sister chromatid cohesion 1 -2.0285
PRPF31 pre-mRNA processing factor 31 -2.02803
TUBA3E tubulin, alpha 3e -2.02465
NOP16 NOP16 nucleolar protein -2.02273
LIN37 lin-37 DREAM MuvB core complex component -2.0193
NUAK2 NUAK family, SNF1-like kinase, 2 -2.01655
GJA1 gap junction protein, alpha 1, 43kDa -2.0138
TWNK twinkle mtDNA helicase -2.01085
CD180 CD180 molecule -2.00995
NR2F1 nuclear receptor subfamily 2, group F, member 1 -2.0094
SPON1 spondin 1, extracellular matrix protein -2.00833
PEX11A peroxisomal biogenesis factor 11 alpha -2.00778
ZNF318 zinc finger protein 318 -2.00363
BCL2A1 BCL2-related protein A1 -2.0027
H2AC7 H2A clustered histone 7 -2.00075