CRCGN016_MCF10A.WT.HP_24H:E23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o,o-dimethyl s-[(4-oxo-1,2,3-benzotriazin-3(4h)-yl)methyl] dithiophosphate 33.95 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:E23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BAMBI BMP and activin membrane-bound inhibitor 4.41068
OXSR1 oxidative stress responsive 1 3.50538
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.2386
NCK2 NCK adaptor protein 2 3.11511
TBX2 T-box 2 3.03814
NUCB2 nucleobindin 2 2.81358
WIF1 WNT inhibitory factor 1 2.71939
CADM1 cell adhesion molecule 1 2.2135
WDR41 WD repeat domain 41 2.09818

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -6.90783
HOXA5 homeobox A5 -6.81154
MSMO1 methylsterol monooxygenase 1 -3.23045
FASTKD5 FAST kinase domains 5 -3.22435
CAB39 calcium binding protein 39 -3.16872
SCYL3 SCY1-like 3 (S. cerevisiae) -3.03996
ALDOC aldolase C, fructose-bisphosphate -2.98719
HMG20B high mobility group 20B -2.86787
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.82268
HSPA8 heat shock 70kDa protein 8 -2.79407
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.78586
GADD45B growth arrest and DNA-damage-inducible, beta -2.56094
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.52934
HOXA4 homeobox A4 -2.48086
TRIM68 tripartite motif containing 68 -2.40232
TRAPPC3 trafficking protein particle complex 3 -2.40071
LYPLA1 lysophospholipase I -2.30946
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.23986
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -2.2099
MELK maternal embryonic leucine zipper kinase -2.19839
RNF19B ring finger protein 19B -2.17847
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.1269
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.11123
ACAA1 acetyl-CoA acyltransferase 1 -2.07766
CANT1 calcium activated nucleotidase 1 -2.01731