CRCGN016_MCF10A.WT.HP_24H:F01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hc blue no. 2 100.97 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GARRE1 granule associated Rac and RHOG effector 1 4.3274
COMP cartilage oligomeric matrix protein 3.8935
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 3.6865
VGLL4 vestigial-like family member 4 3.52365
PRKCQ protein kinase C, theta 3.3406
HMOX1 heme oxygenase 1 2.8269
CNPY3 canopy FGF signaling regulator 3 2.7792
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.608
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 2.32005
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.30625

decreased expression

Symbol Name Standardized Value
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -5.66345
ANXA2 annexin A2 -5.25005
TUBB6 tubulin, beta 6 class V -5.2041
TIMP1 TIMP metallopeptidase inhibitor 1 -5.12995
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.84165
YME1L1 YME1-like 1 ATPase -4.04338
BASP1 brain abundant, membrane attached signal protein 1 -3.647
DERA deoxyribose-phosphate aldolase (putative) -3.3556
KDM3A lysine (K)-specific demethylase 3A -2.5391
TBCB tubulin folding cofactor B -2.3661
CAVIN3 caveolae associated protein 3 -2.29775
TRAP1 TNF receptor-associated protein 1 -2.19075
ARL14 ADP-ribosylation factor-like 14 -2.10335
ABI1 abl-interactor 1 -2.09175
BPHL biphenyl hydrolase-like (serine hydrolase) -2.024